Patents Assigned to The Secretary of State for Defence in her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland of Defence Evaluation and Research Agency
  • Patent number: 6337420
    Abstract: An electroclinic device having two spaced cell walls each bearing electrode structures and treated on at least one facing surface with an alignment layer, a layer of a smectic liquid crystal material enclosed between the cell walls, where the liquid crystal material contains one or more of the compounds described by formula I as defined in the specification.
    Type: Grant
    Filed: March 7, 2000
    Date of Patent: January 8, 2002
    Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland Defence Evaluation Research Agency
    Inventors: Andrew John Slaney, Damien Gerard McDonnell, Amarjit Kaur Samra, Maurice Stanley, Victoria Minter, John William Goodby, Michael Hird, Simon John Cross, Chu Chuan Dong
  • Patent number: 6096734
    Abstract: Susceptible tumors are treated by first sensitizing them to incident electromagnetic radiation by of a compound of the formula: ##STR1## where M is a diamagnetic metal ion or a diamagnetic metal compound or silicon or a compound of silicon or is 2H; one H being bonded to each of the two nitrogen atoms depicted as being bonded to M at positions 29 and 31;R.sub.1 to R.sub.25 are the same or different and are independently selected from C.sub.1 -C.sub.20, alkyl, C.sub.2 -C.sub.20 alkenyl, X--O--Y, ##STR2## X.sup.2 COOX.sup.1, x.sup.2 COONR.sup.1 R.sup.11 and H; wherein X and X.sub.2 are independently selected from a chemical bond, --(CH.sub.2).sub.n -- where n is an integer from 1 to 20 and --(CH.sub.2).sub.a CH.dbd.CH(CH.sub.2).sub.b where a and b are independently selected from integers 0-20 and a+b totals from 0 to 20;X.sup.1 is independently selected from C.sub.1-20 alkyl, C.sub.2-20 alkenyl and H;R.sup.1 and R.sup.11 are independently selected from H, C.sub.1-20 alkyl, C.sub.
    Type: Grant
    Filed: August 24, 1998
    Date of Patent: August 1, 2000
    Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland of Defence and Evaluation Research Agency
    Inventors: David A Russell, Michael J Cook
  • Patent number: 5980978
    Abstract: Semiconductor devices are prepared by growth of epitaxial layers on a substrate from metalorganic compounds of the formula MR.sub.3, R being an alkyl group, or its amine adduct. The metalorganic compound was prepared by reacting a Grignard reagent with a metal halide in an amine solvent.
    Type: Grant
    Filed: July 14, 1997
    Date of Patent: November 9, 1999
    Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland of Defence Evaluation and Research Agency
    Inventors: Anthony Copeland Jones, Simon Andrew Rushworth, Trevor Martin, Timothy John Whittaker, Richard William Freer
  • Patent number: 5922460
    Abstract: A metal matrix composite material made of a fiber reinforcement having a coating of gadolinium and gadolinium boride, preferably as discrete layers, each having a thickness of 1 to 6 microns. This composite is made by coating reinforcing fibers with gadolinium using a deposition technique, further coating the fibers with gadolinium boride by a deposition technique and then consolidating the coated fibers into a metal matrix to form the metal matrix composite.
    Type: Grant
    Filed: May 21, 1997
    Date of Patent: July 13, 1999
    Assignee: The Secretary of State for Defence in her Britannic Majesty's Government of the United Kingdom of Great Britain & Northern Ireland of Defence Evaluation and Research Agency
    Inventors: Charles M. Ward-Close, Francis H. Froes, Deepak Upadhyaya, Panos Tsakiropoulos
  • Patent number: 5877834
    Abstract: A polymer having spontaneous polarization with the same codes as liquid crystal is introduced into a liquid crystal layer of the smectic liquid crystal cell so that the responding speed is improved (second liquid crystal cell). In another way, a polymer having spontaneous polarization with opposite codes to the liquid crystal is introduced into liquid crystal showing .tau.-V.sub.min characteristic so that a driving voltage is lowered (first liquid crystal cell). These polymers are previously added to a liquid crystal composite before injecting into the liquid crystal cell. In another way, after a photochemically polymeric monomer is added to the liquid crystal composite and the obtained product is injected into the liquid crystal cell, the monomer is polymerized by the projection of a light. Furthermore, the liquid crystal cell into which the polymer is introduced is heated again so as to show I phase and is cooled so that the tone display is realized.
    Type: Grant
    Filed: March 21, 1997
    Date of Patent: March 2, 1999
    Assignees: Sharp Kabushiki Kaisha, The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland, The Defence Evaluation and Research Agency
    Inventors: Teiyu Sako, Aya Miyazaki, Akira Sakaigawa, Mitsuhiro Koden
  • Patent number: 5861109
    Abstract: Liquid crystal compounds of formula I may be used by themselves or they may be mixed with other liquid crystal compounds to give useful liquid crystal mixtures which may then be used in liquid crystal devices. The materials exhibit smectic mesophases and may therefore be used in ferroelectric, ferrielectric, antiferroelectric, themochromic and electroclinic devices. They may also be used as long pitch materials.
    Type: Grant
    Filed: January 24, 1996
    Date of Patent: January 19, 1999
    Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland of Defence Evaluation Research Agency
    Inventors: John W. Goodby, Peter Styring, Christa Loubser, Philippus L Wessels
  • Patent number: 5837465
    Abstract: Luciferase is conjugated to a chemical entity, particularly to a specific binding agent such as an antibody, antigen or a nucleic acid, and more particularly an antibody, by (a) mixing the luciferase with one or more of D-luciferin, magnesium ions and adenosine triphosphate and (b) performing a covalent coupling reaction between the luciferase and the binding reagent using a covalent coupling reagent where the amount of D-luciferin, magnesium ions and/or adenosine triphosphate is sufficient to protect the luciferase activity against inhibition by the covalent coupling reagent. Preferably, step (a) is carried out by mixing the luciferase with its substrates in solution and preferably both magnesium and adenosine triphosphate are present as magnesium adenosine triphosphate (Mg.sup.2+ ATP), optionally together with D-luciferin. Also disclosed is a labeled chemical entity comprising a chemical entity conjugated to active luciferase as formed by the method.
    Type: Grant
    Filed: February 28, 1997
    Date of Patent: November 17, 1998
    Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland of Defence Evaluation & Research Agency
    Inventors: David James Squirrell, Melanie Jane Murphy
  • Patent number: 5834455
    Abstract: Compounds of formula (I) are usefully employed in pharmaceutical compositions either in a mixture or in association with a pharmaceutically acceptable carrier or diluent; ##STR1## wherein M is a diamagnetic metal atom or a diamagnetic metal compound of silicon or a compound of silicon or is 2H; one H being bonded to each of the two nitrogen atoms depicted as being bonded to M (positions 29 and 31 shown); R.sub.1 to R.sub.25 are the same or different and are independently selected from C.sub.1 -C.sub.20 alkyl, C.sub.2 -C.sub.20 alkenyl, X--O--Y, (a), X.sup.2 COOX.sup.1, X.sup.2 CONR.sup.1 R.sup.11 and H; wherein X and X.sup.2 are independently selected from a chemical bond, --(CH.sub.2).sub.n -- where n is an integer from 1 to 20 and --(CH.sub.2).sub.a CH.dbd.CH(CH.sub.2).sub.b where a and b are independently selected from integers 0-20 and a+b totals from 0 to 20; X.sup.1 is independently selected from C.sub.1-20 alkyl, C.sub.2-20 alkenyl and H, R.sup.1 and R.sup.11 are independently selected from H, C.sub.
    Type: Grant
    Filed: February 13, 1996
    Date of Patent: November 10, 1998
    Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland of Defence & Evaluation Research Agency, DRA
    Inventors: David A Russell, Michael J Cook
  • Patent number: 5798214
    Abstract: A method is provided for determining the presence and/or amount of a microorganism and/or its intracellular material present in a sample performed by: (a) exposing the sample to a specific binding agent that has been immobilized upon a solid substrate, the specific binding agent being capable of binding to the microorganism or its intracellular material such that it becomes associated with the solid substrate, (b) exposing the solid substrate to an agent capable of making adenylate kinase associated with the microorganism and/or its intracellular material accessible to solutions applied to the substrate, (c) applying a solution containing adenosine diphosphate (ADP) to the substrate under conditions whereby adenosine triphosphate (ATP) may be produced by any adenylate kinase present, and (d) measuring the amount of adenosine triphosphate (ATP) and relating that to the presence and/or amount of microorganism or intracellular contents.
    Type: Grant
    Filed: January 6, 1997
    Date of Patent: August 25, 1998
    Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland of Defence Evaluation and Research Agency
    Inventor: David James Squirrell
  • Patent number: 5741604
    Abstract: A method of applying a stable intermetallic diffusion barrier layer to a metallic article is described. In many instances, protective coatings are incompatible with the material of the substrate to which they are applied. Such incompatibility is overcome in the invention through in situ formation of an intermediate stable diffusion barrier layer by sequential deposition and subsequent reaction of suitable metals to form a continuous intermetallic layer. A conventional overlay coating may then be applied to the intermetallic layer without risk to the underlying substrate. The invention also contemplates creation of unitary diffusion barriers from multi-layer deposits; deposition of plural diffusion barriers, and formation of complete protective systems comprising substrate, diffusion barrier(s) and overlay coating prior to heat treatment in situ.
    Type: Grant
    Filed: October 25, 1995
    Date of Patent: April 21, 1998
    Assignee: The Secretary of State for Defence in her Britannic Majesty's Government of the United Kingdom of Great Britain & Northern Ireland of Defence & Evaluation Research Agency,DRA
    Inventors: Martin J. Deakin, John R. Nicholls
  • Patent number: 5710242
    Abstract: A multi-functional epoxy resin with good high temperature properties allowing prolonged service at temperatures above 120.degree. C. is derived from a precursor of formula (I): ##STR1## in which R.sup.3 to R.sup.8 inclusive are independently selected from hydrogen, C.sub.1 to C.sub.3 alkyl or halo-alkyl and R.sup.9 is hydrogen, alkyl or halogen, and in which n has the value 0, 1 or 2. The precursor (I) may be self-coupled or cross-coupled with precursors of other epoxy compounds of the TGDDM type. Such cross-coupling gives rise to a complex mixture containing not only the mixed product, but also the self-coupled products of each constituent. Regardless of the precise chemical make-up of the mixture, the observed glass transition temperature is higher than for TGDDM resins formed without precursor (I). If the substituent at the R.sup.9 position is alkyl or halogen, oligomer formation is suppressed and a less complex mixture results.
    Type: Grant
    Filed: October 25, 1996
    Date of Patent: January 20, 1998
    Assignee: The Secretary of State for Defence in her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland of Defence Evaluation Research Agency
    Inventors: Peter Johncock, David Alan Jones
  • Patent number: 5701009
    Abstract: Gas detector includes structure (10) defining a gas flow passage (11), means (12) for passing an ultraviolet light beam (13) across the passage, and first and second electrodes (16, 17) downstream of the ultraviolet light means (12), at least one of the first and second electrodes (16, 17) being in the form of a series of electrically separate segments (16a, 17a) extending in a downstream direction, the electrodes (16, 17) being connectable to potential applying means (18) and to means (20) whereby the current passing through each segment (16a, 17a) of a segmented electrode (16, 17) can be measured.
    Type: Grant
    Filed: September 18, 1995
    Date of Patent: December 23, 1997
    Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland of Defence and Evaluation Research Agency
    Inventors: Richard F. Griffiths, Christopher David Jones
  • Patent number: 5684820
    Abstract: A waveguide laser (10) incorporates a guide (12) and two concave resonator mirrors (14, 16). The guide (12) is of square section with side (2a), and of length L equal to 4a.sup.2 /.lambda., where .lambda. is a laser operating wavelength. The mirrors (14, 16) are phase matched to respective Gaussian intensity profile radiation beams with beam waists at respective waveguide end apertures (20, 22). Each beam waist has a radius w.sub.0 in the range 0.1a to 0.65a to avoid waveguide edge effects and excitation of unwanted high order waveguide modes. The laser (10) has good transverse spatial mode characteristics.
    Type: Grant
    Filed: November 21, 1995
    Date of Patent: November 4, 1997
    Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland of Defence and Evaluation Research Agency
    Inventors: Richard M. Jenkins, Christopher A. Hill
  • Patent number: 5684814
    Abstract: A resonant power circuit which supplies pulsed power to a load, such as a pulsed laser, from a d.c. supply by cyclically charging a capacitor. The capacitor is discharged through the load on closure of a switch which should then open to allow the capacitor to re-charge. Occasionally the switch fails to open and the circuit of the invention then develops and applies a reverse voltage to the switch to force it to become open circuit.
    Type: Grant
    Filed: March 26, 1996
    Date of Patent: November 4, 1997
    Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland of Defence Evaluation and Research Agency
    Inventors: Richard Charles Hollins, David Arthur Orchard
  • Patent number: 5675603
    Abstract: A laser device incorporates a rectangular multi-mode beamsplitter waveguide connected at one end to a retro-reflecting mirror. The beamsplitter waveguide is connected at a second end to an output coupling waveguide and a reflection coupling waveguide. The reflection coupling waveguide is terminated by a second retro-reflecting mirror. Radiation produced within the device is reflected by the mirror and coupled to the two coupling waveguides in a manner such that a partially reflecting mirror is not required at an output to the device.
    Type: Grant
    Filed: January 19, 1996
    Date of Patent: October 7, 1997
    Assignee: The Secretary of State for Defence in her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland of Defence Evaluation and Research Agency
    Inventor: Richard M. Jenkins