Abstract: A gas containment and supply apparatus is described consisting of a gas reservoir vessel (1) capable of pressurised gas containment fitted with a gas supply aperture (8) provided with supply means connectable to the gas supply aperture to provide for supply of the gas and control means to control the rate of supply of the gas, in which the gas reservoir is a toroidal pressure vessel comprising a metallic toroidal shell (2) having wound on its surface a tensile load bearing layer of high tensile strength non-metallic fiber (4), the fiber being aligned in a substantially meridional direction on the toroidal shell. Human portable breathing apparatus is described utilising the above.

Abstract: Millimeter wave imaging apparatus for use, in articular, as an indoor security system to identify objects concealed under the clothing of a person in a background scene, including means for generating a millimetric temperature contrast between the person to be imaged and the surroundings in scene. This may be a “hot” or “cold” source for producing a flux, and a relatively smaller flux respectively, of incoherent millimeter wavelength radiation. The apparatus may also include at least one partial ellipsoid reflective enclosure for reflecting millimeter wavelength radiation emitted from the “hot” and “cold” source so as to generate non-localized and uniform illumination of the person. The enclosure may have a metallic inner surface on which a dimpled pattern may be embossed to diffuse the millimeter wavelength radiation reflected from the metallic inner surface.

Abstract: The invention relates to multiplex addressing of a liquid crystal device comprising applying a strobe signal to one of a first plurality of electrodes of the device and a data signal to one of a second plurality of electrodes of the device. The strobe and data signals address a pixel of the device. The data signal comprises one of a SELECT data signal and a NON_SELECT which each have a duration and a discriminating duration which is no longer than the duration. During the discriminating duration the SELECT and NON_SELECT signals are different. The strobe signal comprises a first portion applied simultaneously with the discriminating duration of the data signal and a second portion applied after the discriminating duration of the data signal. By including a section at a larger voltage magnitude in the second portion of the strobe signal than is present in the first part of that signal, improved performance and addressing speed are obtainable.

Abstract: A method of fabricating a micro-mechanical sensor (101) comprising the steps for forming an insulating layer (6) onto the surface of a first wafer (4) bonding a second wafer (2) to the insulating layer (6), patterning and subsequently etching either the first (4) or second wafer (6) such that channels (18,20) are created in either the first (2) or second (4) wafer terminating adjacent the insulating layer (6) and etching the insulating layer (6) to remove portions of the insulating layer (6) below the etched wafer such that those portions of the etched wafer below a predetermined cross section, suspended portions (22), become substantially freely suspended above the un-etched wafer. This method uses Silicon on Insulator technology. Also disclosed is a micro-mechanical gyroscope structure (101) allowing an anisotropic silicon to be used to fabricate a sensor functioning as if fabricated from isotropic silicon.

Abstract: A surface plasmon resonance apparatus for detecting a soluble analyte (e.g. a protein) or a particulate analyte (e.g. a cell), the apparatus comprising: (a) a sensor block adapted to receive a sensor, said sensor, for example a sensor slide, having a metallized sensor surface capable of binding the analyte; (b) a light source capable of generating an evanescent wave at the sensor surface of a sensor slide on the sensor block; (c) a first detector capable of detecting light from the light source which is internally reflected from the sensor surface; and (d) a second detector (e.g. a video camera) capable of detecting light scattered or emitted from an analyte bound thereto. Optionally the apparatus further comprises a second light source for increasing the intensity of the light scattered or emitted from an analyte bound to the sensor surface, preferably, this is sited to such as to minimize the amount of light transmitted therefrom which is detected by the first detector.

Abstract: Disclosed are “acid-amide” calixarenes of formula (I) wherein: L is [—CH2—] or [—O—CH2—O—] and may be the same or different between each aryl group R5 is H, halogen, or C1-C10 aliphatic hydrocarbyl group, C6-C20 aryl group, any of which may optionally be substituted by one or more halo or oxo groups or interrupted by one or more oxo groups, and R5 may be the same or different on each aryl group; R1 comprises an optionally protected carboxy group; two groups out of R2, R3, and R4, are H; the one group out of R2, R3, and R4 not being H comprises an amide group. The amide group may be linked to a second calixarene to form a dimer. Also disclosed are methods of use of such calixarenes for the purposes of metal sequestration, especially of lanthanides and actinides. Also disclosed are calixarene dimer derivatives of the calixarenes of the invention.

Abstract: The invention relates to a method and apparatus for reducing imaging artifacts in physiological images, such as magnetic resonance imaging images. A model of a physical cause for the image artifact is modelled and the effects of perturbing this model on a focus criterion of the image analyzed so as to optimize the focus criterion. For an optimized focus criterion, the model should reflect the actual physical cause of the image artifact. A focus criterion is a measure of entropy of the image, with an optimized image having reduced entropy.

Abstract: A gradiometer for measuring properties of a magnetic field and in particular, for measuring magnetic field gradient components, comprising at least two magnetic sensors wherein at least two of the magnetic sensors are arranged to sense the magnetic field component in substantially the same direction. The magnetic sensors may be super conducting quantum interference device (SQUID) magnetometers, Hall probes, flux gates or magneto-resistive magnetometers. The gradiometer also includes a computer processor loaded with an adaptive signal-processing algorithm, for performing adaptive signal balancing of the magnetometer outputs. In a preferred embodiment the gradiometer may comprise at least eight magnetometers in a three-dimensional arrangement, and a set of three orthogonal global feedback coils, one for each direction x, y, z, such that the five independent magnetic field gradient components may be measured. The gradiometer may also be used to measure second or higher order magnetic field gradient components.

Abstract: An electroclinic device having two spaced cell walls each bearing electrode structures and treated on at least one facing surface with an alignment layer, a layer of a smectic liquid crystal material enclosed between the cell walls, where the liquid crystal material contains one or more of the compounds described by formula I as defined in the specification.

Abstract: 1

Abstract: Activated carbon filters containing transition metals, are prepared by (a) exchanging the transition metal with a cellulose ion exchange material to produce a cellulose material containing the transition metal; (b) charring of the product of (a); activating the product of (b) to form an activated carbon filter having a pore network throughout; and removing surface carbon substantially throughout the pore network of the filter formed in (c). Methods of filtering an atmosphere containing a gaseous contaminant by passing the contaminated atmosphere through a filter made by this process are described.

Abstract: A large core photonic crystal fiber for transmitting radiation having a core comprising a substantially transparent core material and having a core diameter of at least 5 &mgr;. The fiber also comprises a cladding region surrounding the length of core material, wherein the cladding region comprises a first substantially transparent cladding material, having a first refractive index, and wherein the first substantially transparent cladding material has embedded along its length a substantially periodic array of holes, wherein the holes are filled with a second cladding material having a second refractive index less than the first refractive index, such that radiation input to the optical fiber is transmitted along the length of the core material in a single mode of propagation. In a preferred embodiment, the core diameter may be at least 20 &mgr;, and may be as large as 50 &mgr;.

Abstract: Apparatus for effecting reactions, said apparatus comprising a plurality of reaction vessels for holding reagents, an electrically conducting polymer which emits heat when an electric current is passed through it, and control means for controlling supply of current to the polymer, the polymer being connectable to an electrical supply via the control means. The control means may be arranged such that different currents and therefore different temperatures can be achieved in each reaction vessel.

Abstract: A cyclic compound of formula (I) wherein Rx groups which may be the same or different are selected from —O—(CH2)n—O— where n is an integer of from 2-6; Ry and Rz groups which may be the same or different are independently selected from hydrogen, halogen or a hydrocarbyl group; Ra together with Rb of the adjacent phenyl ring and Rc together with Rd of the adjacent phenyl ring form a group of formula —(CH2)m— or —(CH2)p—O— where m and p are integers of from 1-5, and each group Ra-Rb and Rc-Rd may be the same or different; and x is an integer of 2 or more, such as 4. Compounds of formula (I) display particular selectivity for specific ions such as potassium ions. They are useful inter alia in reactions where scavenging of a specific cation is required or as ion specific electrodes.

Abstract: Skin protection agents such as topical compositions which can prevent the passage of toxic chemicals through the skin, such as barrier creams. Formulations may contain hexamethylene tetramine or derivatives or analogues thereof, which react with alkylating agents such as sulfur mustard, and which are suitable for formulation into topical compositions. The formulations additionally may contain perfluorinated polymeric compounds which are effective barrier compounds for a range of toxic chemicals.

Abstract: A method is provided for the formation of liposomes of 0.1 &mgr;m to 50 &mgr;m in diameter having unilamella or multilamella structure and containing water insoluble or undissolved particulate materials comprising (a) forming liposomes and removing substantially all of any organic solvent used in their preparation, (b) freeze drying the liposomes so formed and then (c) rehydrating them in intimate admixture with the particulate material. Preferred encapsulated materials are particulate materials, most preferably microorganisms, plant or animals cells or water insoluble structures having organic solvent labile biochemical or immunological activity, but any water insoluble particulate may be encapsulated using the method. For example, catalysts or drugs that are sparingly soluble may also be so incorporated such that slow release into the patient's body may be provided while release of detergents included in the many lipoome preparation protocols may be avoided.

Abstract: A system and method for determining noise power levels across a range of frequencies of the optical signal output from a device operating at a specified optical power and drive current and, in particular, for determining relative intensity noise values (RIN). The system may comprise a reference laser for generating an optical reference signal and a photodetector for converting the optical signal output from the reference laser and the device under test into equivalent electrical signals. The system also comprises means for measuring ac and dc components of the electrical signals output from the photodetector. The system may be used to measure RIN levels to an accuracy of less than 1 dB. Such measurements are of particular importance in the field of fiber optic telecommunications. The reference laser is shot noise limited in the frequency range of interest, typically between 20 MHz and 20 GHz, and has a narrow linewidth, typically less than 5 kHz.

Abstract: Apparatus for effecting reactions comprising a plurality of reaction vessels for holding reagents, an electrically conducting polymer which emits heat when an electric current is passed through it, and control device for controlling supply of current to the polymer, the polymer being connectable to an electrical supply via the control device. The control device may be arranged such that different currents and therefore different temperatures can be achieved in each reaction vessel. Certain novel reaction vessels are described and claimed. The apparatus are reaction vessels may be used in carrying out reactions which require multiple temperature stages such as amplification reactions such as the polymerase chain reaction.

Abstract: A heuristic processor incorporates a digital arithmetic unit arranged to compute the squared norm of each member of a training data set with respect to each member of a set of centers, and to transform the squared norms in accordance with a nonlinear function to produce training &phgr; vectors. A systolic array arranged for QR decomposition and least mean squares processing forms combinations of the elements of each &phgr; vector to provide a fit to corresponding training answers. The form of combination is then employed with like-transformed to provide estimates of unknown result. The processor is applicable to provide estimated results for problems which are nonlinear and for which explicit mathematical formalisms are unknown.

Abstract: A method, device, and material for providing a fast switching liquid crystal display employs the ferro electric effect of chiral smectic liquid crystal material. To provide a uniform appearance the liquid crystal material is arranged to have a long cholesteric pitch at a temperature close to a smectic/cholesteric phase transistion temperature. This long cholesteric pitch allows liquid crystal molecules to cool from the cholesteric to smectic phase with a uniform alignment. The smectic material is contained in a cell between wells (2, 3) bearing electrodes (5, 6) and surface treated to provide homogeneous alignment of liquid crystal material (7).