Patents Assigned to The South Bohemian University
  • Yeast strain and screening method for identifying inhibitors of the expression of the hexose transporter genes by a positive phenotype
    Patent number: 9121026
    Abstract: The present invention provides screening procedures for identifying inhibitors of components of regulatory networks by a positive phenotype and modified yeast cell lines suitable for said screening. The screening procedures are especially suited to screen for substances that re-sensitize resistant pathogenic microorganisms or tumor cells by suspending the expression of resistance-relevant genes. The invention further provides methods for constructing said cell lines and their use in screening systems.
    Type: Grant
    Filed: November 25, 2005
    Date of Patent: September 1, 2015
    Assignees: The South Bohemian University
    Inventors: Milan Höfer, Jost Ludwig, Petra Schwanewilm, Julius Subik