Patents Assigned to THE SOUTH DAKOTA BOARD OF REGENTS
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Publication number: 20250096312Abstract: The disclosed invention is related to microwave radiation as a method for the synthesis metal-ion solid-state electrolytes from the group known as antiperovskites or inverse perovskites, and more specifically doped or andoped antiperovskites and the use of microwave radiation to synthesize solid-state oxyhalide electrolytes or their doped derivatives with enhanced metal-ion conductivity resulting in higher purity at a lower cost and applicable for large-scale commercial applications.Type: ApplicationFiled: September 18, 2024Publication date: March 20, 2025Applicant: South Dakota Board of RegentsInventors: Alevtina Smirnova, Karen Ly, Kamden Bryant, Collin Rodmire, Fan Zheng
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Publication number: 20250084356Abstract: A custom platform is developed that is capable of culturing endothelial cells three-dimensionally while inducing physiological stimuli on the cells. A model includes serum-free conditions, allowing more quantifiable angiogenesis studies that investigate the dose dependent effects of various growth factors. Angiogenesis plays a critical role during development, wound healing, and disease; therefore, further investigation of the pathway has broad implications. Also, the development of in vitro vascularized tissue models via angiogenesis provides the ability to investigate endothelial responses after exposure to nanoparticles and mechanisms of drug delivery.Type: ApplicationFiled: January 6, 2023Publication date: March 13, 2025Applicant: South Dakota Board of RegentsInventors: Laura A.E. Brunmaier, Travis W. Walker, Cyle Miller, Timothy M. Brenza
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Patent number: 12233129Abstract: Disclosed herein are compositions for treating cancer comprising a modified veratridine. In certain aspects, the modified veratridine comprises a polyglutamic acid (PLE) or polyethylene glycol/polyglutamic acid (PEG-PLE) conjugated to the 4? hemiketal thereof. Further disclosed is a method of treating colorectal cancer in a subject comprising administering to a subject an effective amount of the disclosed compositions.Type: GrantFiled: March 29, 2023Date of Patent: February 25, 2025Assignee: South Dakota Board of RegentsInventors: Khosrow Rezvani, Grigoriy Sereda
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Patent number: 12188926Abstract: An event detection composite in embodiments of the present invention may have one or more of the following features: (a) a plurality of solid and/or hollow and/or porous-wall microspheres, (b) a functional material disposed on or within the plurality of microspheres, wherein the functional material can have unique optical, electrical, magnetic, thermal, or chemical properties, where these properties can be realized upon the plurality of microspheres being exposed to a physical, optical, electrical, magnetic, thermal or chemical stimuli, and (c) a host matrix containing the plurality of microspheres.Type: GrantFiled: July 22, 2019Date of Patent: January 7, 2025Assignees: SOUTH DAKOTA BOARD OF REGENTS, APPLIED RESEARCH CENTERInventors: Grant A Crawford, George G. Wicks, Forest Thompson
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Publication number: 20240417296Abstract: An anaerobic bioreactor with electrolytic regeneration system, method and apparatus for monitoring pH levels which is simultaneously efficient in both anaerobic digestion and optimized filtration process is disclosed. To maintain the pH stability of an anaerobic bioreactor, an electrolysis process is integrated with the bioreactor. The integration of an electrolysis process with the bioreactor sustains the pH in the optimized range for anaerobic process while enhancing the removal of contaminants in the bioreactor, augmenting biogas production, and mitigating fouling.Type: ApplicationFiled: November 3, 2022Publication date: December 19, 2024Applicant: South Dakota Board of RegentsInventors: Maryam Amouamouha, Travis W. Walker
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Patent number: 12122975Abstract: An engine oil additive includes carbon nanotubes and boron nitride particulates dispersed within a fluid. The additive is configured to be mixed with a quantity of oil such that the quantity of oil has a concentration from 0.05 to 0.5 grams of carbon nanotubes and of boron nitride particulates per quart of oil to improve the lubricity of the oil. The additive improves the horsepower and torque of the engine while reducing fuel consumption. The carbon nanotubes have an —OH functionalized exterior surface. The carbon nanotubes have a diameter from 1 nanometer to 50 nanometers and have a length from 1 micron to 1000 microns. The boron nitride particulates are hex-boron nitride structures having an average size from 30 nanometers to 500 nanometers.Type: GrantFiled: April 4, 2022Date of Patent: October 22, 2024Assignees: Novum Nano, LLC, South Dakota Board of RegentsInventors: Craig Bailey, Greg Christensen, Haiping Hong
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Publication number: 20240341325Abstract: The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets.Type: ApplicationFiled: March 18, 2024Publication date: October 17, 2024Applicant: THE SOUTH DAKOTA BOARD OF REGENTS, AS GOVERNING BOARD FOR SOUTH DAKOTA STATE UNIVERSITYInventors: William Gibbons, Michael L. Brown
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Publication number: 20240316583Abstract: Cold spray devices and systems are disclosed. They include a flowpath having an inlet adapted for receiving communication with two or more inputs and an outlet adapted to discharge the two or more inputs. A discharge nozzle may be included in the flowpath of the outlet and a confluence may be included in the flowpath at the inlet for combining the two or more inputs. A nozzle body houses the discharge nozzle separate and downstream from the confluence of the two inputs.Type: ApplicationFiled: June 4, 2024Publication date: September 26, 2024Applicants: South Dakota Board of Regents, GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMYInventors: Christian Widener, Victor Champagne, Matthew Trexler, Dennis Helfritch, Rob Hrabe
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Patent number: 12098354Abstract: The present disclosure describes hydrogels which are micropatterned with a network of wells for cell culture. In a preferred embodiment, the micropatterned hydrogels are embedded with a nanomaterial. Further described are methods of forming the micropatterned hydrogels and methods of culturing cells in the micropatterned hydrogels. The hydrogels can be natural or synthetic.Type: GrantFiled: April 2, 2020Date of Patent: September 24, 2024Assignee: SOUTH DAKOTA BOARD OF REGENTSInventors: Scott Wood, Ram Saraswat
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Patent number: 12084193Abstract: Disclosed herein is a conductive coating composition that includes a functionalized carbon nanomaterial and/or boron nanomaterial and a fluid component. The nanomaterial and fluid component forms hydrogen bond network in the disclosed composition. Because of the formed hydrogen bonds, the disclosed coating exhibits enhanced thermal or electrical conductivity. Also disclosed is a method to improve thermal or electrical conductivity of an existing coating composition.Type: GrantFiled: March 31, 2022Date of Patent: September 10, 2024Assignee: SOUTH DAKOTA BOARD OF REGENTSInventors: Haiping Hong, Christian Widener, Gregory Lee Christensen
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Patent number: 11998942Abstract: Cold spray devices and systems are disclosed. They include a flowpath having an inlet adapted for receiving communication with two or more inputs and an outlet adapted to discharge the two or more inputs. A discharge nozzle may be included in the flowpath of the outlet and a confluence may be included in the flowpath at the inlet for combining the two or more inputs. A nozzle body houses the discharge nozzle separate and downstream from the confluence of the two inputs.Type: GrantFiled: March 2, 2022Date of Patent: June 4, 2024Assignees: South Dakota Board of Regents, GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMYInventors: Christian Widener, Victor Champagne, Matthew Trexler, Dennis Helfritch, Rob Hrabe
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Patent number: 11996222Abstract: The present disclosure addresses limitations in ferritic materials. In at least one aspect, the present disclosure provides core-shell nanoparticles exhibiting improved characteristics for implementations and adoptability in numerous applications. Further aspects of the disclosure provide core-shell nanoparticles for use in electronic, magnetic and electro-magnetic applications. Still, other aspects of the present disclosure provide core-shell nanoparticles for a thermochemical water-splitting reaction resulting in increased H2 volume generation during multiple thermochemical cycles.Type: GrantFiled: March 6, 2019Date of Patent: May 28, 2024Assignee: SOUTH DAKOTA BOARD OF REGENTSInventors: Rajesh V. Shende, Jan A. Puszynski, Vinod S. Amar
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Patent number: 11992028Abstract: The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets.Type: GrantFiled: September 27, 2022Date of Patent: May 28, 2024Assignee: The South Dakota Board of Regents, as Governing Board for South Dakota State UniversityInventors: William Gibbons, Michael L Brown
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Patent number: 11955626Abstract: The present disclosure relates to mixed ionically and electronically conducting solid-state phases for their application in electrochemical devices, such as lithium-metal or lithium ion batteries. The solid-state mixed phase comprises of active cathode and carbon-based structures functionalized by a heteropolyacid (HPA) or a metal salt of a heteropolyacid (Me-HPA) to form a solid-state architecture with incorporated ceramic or glass-ceramic electrolyte for enhanced ionic and electronic conductivity pathways. Combining the solid-state phase components in melted solid-state electrolyte results in perfect distribution, improved adhesion between particles, and improved characteristics of the electrochemical device, such as high charge rates, long-term performance, and broad voltage window.Type: GrantFiled: August 17, 2021Date of Patent: April 9, 2024Assignee: SOUTH DAKOTA BOARD OF REGENTSInventors: Alevtina Smirnova, Abu Md Numan-Al-Mobin
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Patent number: 11905609Abstract: The present invention relates to a one-step process for preparation of “in-situ” or “ex-situ” self-organized and electrically conducting polymer nanocomposites using thermally initiated polymerization of a halogenated 3,4-ethylenedioxythiophene monomer or its derivatives. This approach does not require additional polymerization initiators or catalysts, produce gaseous products that are naturally removed without affecting the polymer matrix, and do not leave by-product contaminants. It is demonstrated that self-polymerization of halogenated 3,4-ethylenedioxythiophene monomer is not affected by the presence of a solid-state phase in the form of nanoparticles and results in formation of 3,4-polyethylenedioxythiophene (PEDOT) nanocomposites.Type: GrantFiled: August 5, 2021Date of Patent: February 20, 2024Assignee: SOUTH DAKOTA BOARD OF REGENTSInventors: Alevtina Smirnova, Michael McGraw, Praveen Kolla
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Patent number: 11896031Abstract: The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets.Type: GrantFiled: January 21, 2022Date of Patent: February 13, 2024Assignee: The South Dakota Board of Regent, as Governing Board for South Dakota State UniversityInventors: William Gibbons, Michael Brown
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Patent number: 11824189Abstract: This application relates to anode compositions and methods of making and using the same. In particular, the anode compositions are preferably layered. Preferably, the methods of making the anode compositions comprise a surfactant mediated assembly of layers. The anode compositions have improved structural integrity and capacity while reducing capacity fade due to cycling.Type: GrantFiled: October 22, 2019Date of Patent: November 21, 2023Assignee: SOUTH DAKOTA BOARD OF REGENTSInventors: David R. Salem, Chunhui Chen, Abdulmenan Hussein
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Patent number: 11806657Abstract: An impact test apparatus can be used to determine particle interfacial energies with varying relative air humidity. It was observed that capillary condensation increased the adhesive forces of hydrophilic materials. A systems humidity separation window was identified and the differences in interfacial energy for a hydrophilic surface and for a hydrophobic surface can be exploited in order to achieve the separation of particles. Separation and concentration of particles, particularly particles within a mineral ore body, can be obtained.Type: GrantFiled: September 3, 2021Date of Patent: November 7, 2023Assignee: SOUTH DAKOTA BOARD OF REGENTSInventors: Bernado Moreno Baqueiro Sansao, Jon Kellar, William Cross, Albert Romkes
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Patent number: 11800882Abstract: The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets.Type: GrantFiled: September 17, 2021Date of Patent: October 31, 2023Assignee: The South Dakota Board of Regents, as Governing Board for South Dakota State UniversityInventors: William Gibbons, Michael L. Brown
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Patent number: 11796510Abstract: A system for determining gas characteristics at high altitudes in embodiments of the present invention may have one or more of the following features: (a) a high-altitude balloon having one or more of the following features: (a) a balloon, (b) a balloonsat operably coupled to the balloon, (c) an air path chamber wherein gas at a high altitude can occupy the air path chamber, (d) a first speaker located on a substrate within the air path chamber, wherein the first speaker takes an electrical signal input and creates a first sound wave, and (e) a second speaker located on the substrate facing opposite of the first speaker located outside of the air path chamber, wherein the second speaker takes the electrical signal and creates a second sound wave.Type: GrantFiled: April 30, 2021Date of Patent: October 24, 2023Assignee: SOUTH DAKOTA BOARD OF REGENTSInventors: Lowell Kolb, Charles Tolle, Nathan Williams, Jason Ash