Patents Assigned to THE SOUTH DAKOTA BOARD OF REGENTS
  • Publication number: 20250096312
    Abstract: The disclosed invention is related to microwave radiation as a method for the synthesis metal-ion solid-state electrolytes from the group known as antiperovskites or inverse perovskites, and more specifically doped or andoped antiperovskites and the use of microwave radiation to synthesize solid-state oxyhalide electrolytes or their doped derivatives with enhanced metal-ion conductivity resulting in higher purity at a lower cost and applicable for large-scale commercial applications.
    Type: Application
    Filed: September 18, 2024
    Publication date: March 20, 2025
    Applicant: South Dakota Board of Regents
    Inventors: Alevtina Smirnova, Karen Ly, Kamden Bryant, Collin Rodmire, Fan Zheng
  • Publication number: 20250084356
    Abstract: A custom platform is developed that is capable of culturing endothelial cells three-dimensionally while inducing physiological stimuli on the cells. A model includes serum-free conditions, allowing more quantifiable angiogenesis studies that investigate the dose dependent effects of various growth factors. Angiogenesis plays a critical role during development, wound healing, and disease; therefore, further investigation of the pathway has broad implications. Also, the development of in vitro vascularized tissue models via angiogenesis provides the ability to investigate endothelial responses after exposure to nanoparticles and mechanisms of drug delivery.
    Type: Application
    Filed: January 6, 2023
    Publication date: March 13, 2025
    Applicant: South Dakota Board of Regents
    Inventors: Laura A.E. Brunmaier, Travis W. Walker, Cyle Miller, Timothy M. Brenza
  • Patent number: 12233129
    Abstract: Disclosed herein are compositions for treating cancer comprising a modified veratridine. In certain aspects, the modified veratridine comprises a polyglutamic acid (PLE) or polyethylene glycol/polyglutamic acid (PEG-PLE) conjugated to the 4? hemiketal thereof. Further disclosed is a method of treating colorectal cancer in a subject comprising administering to a subject an effective amount of the disclosed compositions.
    Type: Grant
    Filed: March 29, 2023
    Date of Patent: February 25, 2025
    Assignee: South Dakota Board of Regents
    Inventors: Khosrow Rezvani, Grigoriy Sereda
  • Patent number: 12188926
    Abstract: An event detection composite in embodiments of the present invention may have one or more of the following features: (a) a plurality of solid and/or hollow and/or porous-wall microspheres, (b) a functional material disposed on or within the plurality of microspheres, wherein the functional material can have unique optical, electrical, magnetic, thermal, or chemical properties, where these properties can be realized upon the plurality of microspheres being exposed to a physical, optical, electrical, magnetic, thermal or chemical stimuli, and (c) a host matrix containing the plurality of microspheres.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: January 7, 2025
    Assignees: SOUTH DAKOTA BOARD OF REGENTS, APPLIED RESEARCH CENTER
    Inventors: Grant A Crawford, George G. Wicks, Forest Thompson
  • Publication number: 20240417296
    Abstract: An anaerobic bioreactor with electrolytic regeneration system, method and apparatus for monitoring pH levels which is simultaneously efficient in both anaerobic digestion and optimized filtration process is disclosed. To maintain the pH stability of an anaerobic bioreactor, an electrolysis process is integrated with the bioreactor. The integration of an electrolysis process with the bioreactor sustains the pH in the optimized range for anaerobic process while enhancing the removal of contaminants in the bioreactor, augmenting biogas production, and mitigating fouling.
    Type: Application
    Filed: November 3, 2022
    Publication date: December 19, 2024
    Applicant: South Dakota Board of Regents
    Inventors: Maryam Amouamouha, Travis W. Walker
  • Patent number: 12122975
    Abstract: An engine oil additive includes carbon nanotubes and boron nitride particulates dispersed within a fluid. The additive is configured to be mixed with a quantity of oil such that the quantity of oil has a concentration from 0.05 to 0.5 grams of carbon nanotubes and of boron nitride particulates per quart of oil to improve the lubricity of the oil. The additive improves the horsepower and torque of the engine while reducing fuel consumption. The carbon nanotubes have an —OH functionalized exterior surface. The carbon nanotubes have a diameter from 1 nanometer to 50 nanometers and have a length from 1 micron to 1000 microns. The boron nitride particulates are hex-boron nitride structures having an average size from 30 nanometers to 500 nanometers.
    Type: Grant
    Filed: April 4, 2022
    Date of Patent: October 22, 2024
    Assignees: Novum Nano, LLC, South Dakota Board of Regents
    Inventors: Craig Bailey, Greg Christensen, Haiping Hong
  • Publication number: 20240341325
    Abstract: The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets.
    Type: Application
    Filed: March 18, 2024
    Publication date: October 17, 2024
    Applicant: THE SOUTH DAKOTA BOARD OF REGENTS, AS GOVERNING BOARD FOR SOUTH DAKOTA STATE UNIVERSITY
    Inventors: William Gibbons, Michael L. Brown
  • Publication number: 20240316583
    Abstract: Cold spray devices and systems are disclosed. They include a flowpath having an inlet adapted for receiving communication with two or more inputs and an outlet adapted to discharge the two or more inputs. A discharge nozzle may be included in the flowpath of the outlet and a confluence may be included in the flowpath at the inlet for combining the two or more inputs. A nozzle body houses the discharge nozzle separate and downstream from the confluence of the two inputs.
    Type: Application
    Filed: June 4, 2024
    Publication date: September 26, 2024
    Applicants: South Dakota Board of Regents, GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY
    Inventors: Christian Widener, Victor Champagne, Matthew Trexler, Dennis Helfritch, Rob Hrabe
  • Patent number: 12098354
    Abstract: The present disclosure describes hydrogels which are micropatterned with a network of wells for cell culture. In a preferred embodiment, the micropatterned hydrogels are embedded with a nanomaterial. Further described are methods of forming the micropatterned hydrogels and methods of culturing cells in the micropatterned hydrogels. The hydrogels can be natural or synthetic.
    Type: Grant
    Filed: April 2, 2020
    Date of Patent: September 24, 2024
    Assignee: SOUTH DAKOTA BOARD OF REGENTS
    Inventors: Scott Wood, Ram Saraswat
  • Patent number: 12084193
    Abstract: Disclosed herein is a conductive coating composition that includes a functionalized carbon nanomaterial and/or boron nanomaterial and a fluid component. The nanomaterial and fluid component forms hydrogen bond network in the disclosed composition. Because of the formed hydrogen bonds, the disclosed coating exhibits enhanced thermal or electrical conductivity. Also disclosed is a method to improve thermal or electrical conductivity of an existing coating composition.
    Type: Grant
    Filed: March 31, 2022
    Date of Patent: September 10, 2024
    Assignee: SOUTH DAKOTA BOARD OF REGENTS
    Inventors: Haiping Hong, Christian Widener, Gregory Lee Christensen
  • Patent number: 11998942
    Abstract: Cold spray devices and systems are disclosed. They include a flowpath having an inlet adapted for receiving communication with two or more inputs and an outlet adapted to discharge the two or more inputs. A discharge nozzle may be included in the flowpath of the outlet and a confluence may be included in the flowpath at the inlet for combining the two or more inputs. A nozzle body houses the discharge nozzle separate and downstream from the confluence of the two inputs.
    Type: Grant
    Filed: March 2, 2022
    Date of Patent: June 4, 2024
    Assignees: South Dakota Board of Regents, GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY
    Inventors: Christian Widener, Victor Champagne, Matthew Trexler, Dennis Helfritch, Rob Hrabe
  • Patent number: 11996222
    Abstract: The present disclosure addresses limitations in ferritic materials. In at least one aspect, the present disclosure provides core-shell nanoparticles exhibiting improved characteristics for implementations and adoptability in numerous applications. Further aspects of the disclosure provide core-shell nanoparticles for use in electronic, magnetic and electro-magnetic applications. Still, other aspects of the present disclosure provide core-shell nanoparticles for a thermochemical water-splitting reaction resulting in increased H2 volume generation during multiple thermochemical cycles.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: May 28, 2024
    Assignee: SOUTH DAKOTA BOARD OF REGENTS
    Inventors: Rajesh V. Shende, Jan A. Puszynski, Vinod S. Amar
  • Patent number: 11992028
    Abstract: The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets.
    Type: Grant
    Filed: September 27, 2022
    Date of Patent: May 28, 2024
    Assignee: The South Dakota Board of Regents, as Governing Board for South Dakota State University
    Inventors: William Gibbons, Michael L Brown
  • Patent number: 11955626
    Abstract: The present disclosure relates to mixed ionically and electronically conducting solid-state phases for their application in electrochemical devices, such as lithium-metal or lithium ion batteries. The solid-state mixed phase comprises of active cathode and carbon-based structures functionalized by a heteropolyacid (HPA) or a metal salt of a heteropolyacid (Me-HPA) to form a solid-state architecture with incorporated ceramic or glass-ceramic electrolyte for enhanced ionic and electronic conductivity pathways. Combining the solid-state phase components in melted solid-state electrolyte results in perfect distribution, improved adhesion between particles, and improved characteristics of the electrochemical device, such as high charge rates, long-term performance, and broad voltage window.
    Type: Grant
    Filed: August 17, 2021
    Date of Patent: April 9, 2024
    Assignee: SOUTH DAKOTA BOARD OF REGENTS
    Inventors: Alevtina Smirnova, Abu Md Numan-Al-Mobin
  • Patent number: 11905609
    Abstract: The present invention relates to a one-step process for preparation of “in-situ” or “ex-situ” self-organized and electrically conducting polymer nanocomposites using thermally initiated polymerization of a halogenated 3,4-ethylenedioxythiophene monomer or its derivatives. This approach does not require additional polymerization initiators or catalysts, produce gaseous products that are naturally removed without affecting the polymer matrix, and do not leave by-product contaminants. It is demonstrated that self-polymerization of halogenated 3,4-ethylenedioxythiophene monomer is not affected by the presence of a solid-state phase in the form of nanoparticles and results in formation of 3,4-polyethylenedioxythiophene (PEDOT) nanocomposites.
    Type: Grant
    Filed: August 5, 2021
    Date of Patent: February 20, 2024
    Assignee: SOUTH DAKOTA BOARD OF REGENTS
    Inventors: Alevtina Smirnova, Michael McGraw, Praveen Kolla
  • Patent number: 11896031
    Abstract: The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets.
    Type: Grant
    Filed: January 21, 2022
    Date of Patent: February 13, 2024
    Assignee: The South Dakota Board of Regent, as Governing Board for South Dakota State University
    Inventors: William Gibbons, Michael Brown
  • Patent number: 11824189
    Abstract: This application relates to anode compositions and methods of making and using the same. In particular, the anode compositions are preferably layered. Preferably, the methods of making the anode compositions comprise a surfactant mediated assembly of layers. The anode compositions have improved structural integrity and capacity while reducing capacity fade due to cycling.
    Type: Grant
    Filed: October 22, 2019
    Date of Patent: November 21, 2023
    Assignee: SOUTH DAKOTA BOARD OF REGENTS
    Inventors: David R. Salem, Chunhui Chen, Abdulmenan Hussein
  • Patent number: 11806657
    Abstract: An impact test apparatus can be used to determine particle interfacial energies with varying relative air humidity. It was observed that capillary condensation increased the adhesive forces of hydrophilic materials. A systems humidity separation window was identified and the differences in interfacial energy for a hydrophilic surface and for a hydrophobic surface can be exploited in order to achieve the separation of particles. Separation and concentration of particles, particularly particles within a mineral ore body, can be obtained.
    Type: Grant
    Filed: September 3, 2021
    Date of Patent: November 7, 2023
    Assignee: SOUTH DAKOTA BOARD OF REGENTS
    Inventors: Bernado Moreno Baqueiro Sansao, Jon Kellar, William Cross, Albert Romkes
  • Patent number: 11800882
    Abstract: The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets.
    Type: Grant
    Filed: September 17, 2021
    Date of Patent: October 31, 2023
    Assignee: The South Dakota Board of Regents, as Governing Board for South Dakota State University
    Inventors: William Gibbons, Michael L. Brown
  • Patent number: 11796510
    Abstract: A system for determining gas characteristics at high altitudes in embodiments of the present invention may have one or more of the following features: (a) a high-altitude balloon having one or more of the following features: (a) a balloon, (b) a balloonsat operably coupled to the balloon, (c) an air path chamber wherein gas at a high altitude can occupy the air path chamber, (d) a first speaker located on a substrate within the air path chamber, wherein the first speaker takes an electrical signal input and creates a first sound wave, and (e) a second speaker located on the substrate facing opposite of the first speaker located outside of the air path chamber, wherein the second speaker takes the electrical signal and creates a second sound wave.
    Type: Grant
    Filed: April 30, 2021
    Date of Patent: October 24, 2023
    Assignee: SOUTH DAKOTA BOARD OF REGENTS
    Inventors: Lowell Kolb, Charles Tolle, Nathan Williams, Jason Ash