Abstract: The present disclosure relates to the field of decontamination and biocidal agents. More specifically, the invention relates to novel N-halamine melamine derivatives, compositions comprising them, processes for their production, and methods using the same.
Type:
Application
Filed:
October 14, 2016
Publication date:
April 19, 2018
Applicant:
State of Israel Prime Minister's Office Israel Institute For Biological Research
Abstract: The invention provides an isolated Bacillus cereus sensu lato strain, selected from Bacillus anthracis, Bacillus cereus and Bacillus thuringiensis, in which the htrA gene or any part thereof is silenced, and vaccines comprising the same.
Type:
Grant
Filed:
July 18, 2012
Date of Patent:
July 25, 2017
Assignee:
State of Israel Prime Minister's Office Israel Institute for Biological Research
Inventors:
Ofer Cohen, Theodor Chitlaru, Avigdor Shafferman
Abstract: The invention provides an isolated Bacillus cereus sensu lato strain, selected from Bacillus anthracis, Bacillus cereus and Bacillus thuringiensis, in which the htrA gene or any part thereof is silenced, and vaccines comprising the same.
Type:
Application
Filed:
July 18, 2012
Publication date:
June 19, 2014
Applicant:
STATE OF ISRAEL PRIME MINISTER'S OFFICE ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH
Inventors:
Ofer Cohen, Theodor Chitlaru, Avigdor Shafferman
Abstract: A protective agent suitable to protect the human skin against lesions caused by vesicants or other percutaneous chemical agents, particularly against sulfur mustard gas injury and VX intoxication, which comprises a protective-effective amount of a hydrophilic water-based cream, alone or together with one or more additives selected from among the group consisting essentially of polyols, mono-, oligo- or polysaccharides, and salts of organic or inorganic acids. The additive polyol may be glycol, propylene glycol, polyglycerol, glycerin, sorbitol, dulcitol, tritol, sorbitol or mannitol. The additive monosaccharide may be ribose, xylose, glucose, fructose, galactose or mannose. The additive oligosaccharide may be sucrose, maltose, lactose, raffinose or cellobiose.
Type:
Grant
Filed:
December 31, 2001
Date of Patent:
November 17, 2009
Assignee:
State of Israel Prime Minister's Office-Israel Institute of Biological Research
Inventors:
Itzhak Barness, Tamar Kadar, Eliezer Fishbine
Abstract: A circulatory long-lived cholinesterase (ChE) protein, such as acetylcholinesterase (AChE) or butyrylcholinesterase (BChE), which is a ChE protein modified with a non-antigenic polymer. The ChE may be AChE, such as native AChE of mammalian origin or of non-mammalian origin, or recombinant AChE. The recombinant AChE may be mutated at one or more amino-acid residues. The BChE may be native BChE of mammalian origin or of non-mammalian origin.
Type:
Grant
Filed:
April 25, 2002
Date of Patent:
August 11, 2009
Assignee:
State of Israel Prime Minister's Office Israel Institute for Biological Research
Abstract: There is provided genetically engineered bovine interferon of the IFN-.alpha.-type and various sub-types thereof. There is further provided a double stranded DNA molecule which includes DNA encoding BoIFN-.alpha. A, BoIFN0.alpha. B, BoIFN-.alpha. C, and BoIFN-.alpha. D, and cloning vehicles including such DNAs. There are further provided cells including such DNA and a process for the production of such types of BoIFN based on the use of such cells. Furthermore, there is also provided a method for the identification of a bovine IFN-.alpha. DNA sequence.
Type:
Grant
Filed:
April 9, 1985
Date of Patent:
October 31, 1989
Assignee:
State of Israel, Prime Minister's Office, Israel Institute for Biological Research
Inventors:
Baruch Velan, Sara Cohen, Haim Grosfeld, Avigdor Shafferman
Abstract: Organo-phosphorus compounds of the general formula ##STR1## wherein Z is a member selected from ##STR2## wherein R and R' are each selected from hydrogen and lower alkyl, R" designates a member selected from methyl and ethyl, and X.sup.- is an anion may be used as active ingredient in pharmaceutical and pesticidal, especially acaricidal and fungicidal, compositions of matter of low mammalian toxicity.
Type:
Grant
Filed:
October 30, 1975
Date of Patent:
September 5, 1978
Assignee:
The State of Israel, Prime Minister's Office, The Israel Institute for Biological Research