Abstract: A new family of antimicrobial proteins is described. Prototype proteins can be isolated from Macadamia integrifolia as well as other plant species. DNA encoding the protein is also described as well as DNA constructs which can be used to express the antimicrobial protein or to introduce the antimicrobial protein into a plant. Compositions comprising the antimicrobial protein or the antimicrobial protein per se can be administered to plants or mammalian animals to combat microbial infestation.
Type:
Grant
Filed:
December 22, 1997
Date of Patent:
June 27, 2006
Assignees:
Commonwealth Scientific and Industrial Research Organisation, The State of Queensland Department of Primary Industries, The University of Queensland, Bureau of Sugar Experiment Stations, Queensland University of Technology
Inventors:
John Michael Manners, John Paul Marcus, Kenneth Clifford Goulter, Jodie Lyn Green, Neil Ivan Bower
Abstract: The subject invention relates to DNA encoding an anti-microbial protein from Macadamia integrifolia and variants of the protein that are less sensitive to Ca++. The invention further relates to constructs comprising the DNA, and host cells, plants and plant material comprising such constructs.
Type:
Grant
Filed:
June 15, 2001
Date of Patent:
June 21, 2005
Assignees:
Commonwealth Scientific and Industrial Research Organisation, The State of Queensland, Department of Primary Industries, The University of Queensland, Bureau of Sugar Experiments Stations, Queensland University of Technology
Inventors:
John Michael Manners, John Paul Marcus, Kenneth Clifford Goulter, Jodie Lyn Green, Stuart John Harrison