Abstract: The present disclosure provides a method of delivery, treatment, and prevention of neuropathy and/or pain associated with NGF treatment for an underline disease or condition with a NGF mutant, such as NGFR100W, that does not elicit pain. The present disclosure further provides a composition of micro- and/or nano-rods attached with the NGF mutant, such as NGFR100W, which are injectable or administered to a target for desired therapies.
Type:
Application
Filed:
August 2, 2021
Publication date:
September 14, 2023
Applicants:
The Regents of the University of California, The Steadman Clinic & Steadman Philippon Research Institute
Inventors:
Chengbiao WU, Kijung SUNG, Chelsea Shileds BAHNEY, Kevin RIVERA, Tejal DESAI
Abstract: Methods of making decellularized tendon matrix (DTM) and DTM hydrogels are provided. These compositions and hydrogels are useful for repairing tendon injuries and in some cases may be used by injection, arthroscopic procedures, or as adjuncts to traditional surgical repair.
Type:
Application
Filed:
June 20, 2021
Publication date:
July 20, 2023
Applicant:
THE STEADMAN CLINIC AND STEADMAN PHILIPPON RESEARCH INSTITUTE
Inventors:
Chelsea S. BAHNEY, David BERNHOLT, Anna-Laura NELSON, Peter J. MILLETT
Abstract: Methods of making decellularized tendon matrix (DTM) and DTM hydrogels are provided. These compositions and hydrogels are useful for repairing tendon injuries and in some cases may be used by injection, arthroscopic procedures, or as adjuncts to traditional surgical repair.
Type:
Application
Filed:
December 20, 2019
Publication date:
February 17, 2022
Applicant:
The Steadman Clinic and Steadman Philippon Research Institute
Inventors:
Chelsea S. BAHNEY, Peter J. MILLETT, David BERNHOLT, Anna-Laura NELSON