Patents Assigned to The Texas A & M University
  • Patent number: 11474952
    Abstract: Methods, systems, and computer readable media for performing page fault handling are disclosed. According to one method, the method includes: after a translation lookaside buffer (TLB) miss associated with a virtual memory page occurs, identifying, in a page table, a page table entry (PTE) associated with the virtual memory page; determining, using a first indicator in the PTE, that the virtual memory page is not present in a main memory; determining, using a second indicator in the PTE, that the virtual memory page is associated with a valid memory address and that the virtual memory page is capable of using pre-allocated pages; obtaining, from a pre-allocation table, a page frame number associated with a pre-allocated page; and updating the PTE to indicate the page frame number.
    Type: Grant
    Filed: June 1, 2021
    Date of Patent: October 18, 2022
    Assignees: The Texas A&M University System, Hewlett Packard Enterprise Development LP
    Inventors: Narasimha Reddy Annapareddy, Chih-Chieh Chou, Chandrahas Tirumulasetty, Paul Gratz, Ayman Abouelwafa
  • Publication number: 20220323913
    Abstract: Provided herein are one-step methods for fabricating an asymmetric mixed-matrix membrane and the asymmetric mixed matrix membrane so fabricated. In the one step method an asymmetric polymer film is formed from a liquid polymer solution and a ligand precursor simultaneously with the formation of metal-organic framework filler particles therein. Also provided is a method for separating a mixture of gases or of liquids by flowing the mixture through the asymmetric mixed matrix membrane.
    Type: Application
    Filed: April 12, 2022
    Publication date: October 13, 2022
    Applicant: Texas A&M University
    Inventors: Hae-Kwon Jeong, Yinying Hua, Sung-Hwan Park
  • Patent number: 11459396
    Abstract: The present disclosure includes a fusion protein, called a “Seldeg”, including a targeting component that specifically binds to a cell surface receptor or other cell surface molecule at near-neutral pH, and an antigen component fused directly or indirectly to the targeting component. The antigen component is configured to specifically bind a target antigen-specific antibody. The present disclosure also includes a method of depleting a target antigen-specific antibody from a patient by administering to the patient a Seldeg having an antigen component configured to specifically bind the target antigen-specific antibody.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: October 4, 2022
    Assignee: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Elizabeth Sally Ward Ober, Venkata Siva Charan Devanaboyina, Raimund Johannes Ober
  • Patent number: 11459439
    Abstract: An embodiment includes a system comprising: a monolithic shape memory polymer (SMP) foam having first and second states; wherein the SMP foam includes: (a) polyurethane, (b) an inner half portion having inner reticulated cells defined by inner struts, (c) an outer half portion, having outer reticulated cells defined by outer struts, surrounding the inner portion in a plane that provides a cross-section of the SMP foam, (d) hydroxyl groups chemically bound to outer surfaces of both the inner and outer struts. Other embodiments are discussed herein.
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: October 4, 2022
    Assignees: Lawrence Livermore National Security, LLC, The Texas A&M University System
    Inventors: Landon D. Nash, Duncan J. Maitland, Nicole Docherty, Thomas S. Wilson, Ward Small, IV, Jason Ortega, Pooja Singhal
  • Patent number: 11446371
    Abstract: The present invention provides methods and compositions to reduce binding of fibrinogen to the ClfA in a gram positive bacterial infections using monoclonal antibody, a polyclonal antibody, an antigen-binding antibody fragment or a composition that specifically binds to a portion of ClfA with the sequence of SEQ ID No: 15, SEQ ID NO: 16, SEQ ID NO: 17, and SEQ ID NO: 18.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: September 20, 2022
    Assignee: The Texas A&M University System
    Inventors: Vannakambadi K. Ganesh, Magnus Hook
  • Publication number: 20220294472
    Abstract: A method and system for decoding low density parity check (“LDPC”) codes. An LDPC code decoder includes LDPC decoding circuitry comprising a Q message generator and a P sum adder array. The Q message generator combines an R message from a previous iteration with a P message to produce a Q message. The P sum adder array adds the P message to a difference of an R message from a current iteration and the R message from the previous iteration to produce an updated P message.
    Type: Application
    Filed: May 13, 2022
    Publication date: September 15, 2022
    Applicant: The Texas A&M University System
    Inventors: Kiran Kumar GUNNAM, Gwan S. CHOI
  • Publication number: 20220288175
    Abstract: Vaccine vectors and methods of using the vaccine vectors to enhance the immune response to an Apicomplexan parasite and reduce the morbidity or mortality associated with subsequent infection are provided herein. The vaccine vectors include a polynucleotide encoding a Rhomboid polypeptide and optionally include an immune-stimulatory polypeptide suitably expressed on the surface of the vaccine vector.
    Type: Application
    Filed: May 25, 2022
    Publication date: September 15, 2022
    Applicants: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS, THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: John R. Barta, Luc Berghman, Srichaitanya Shivaramaiah, Olivia B. Faulkner, Lisa Bielke, Billy Hargis
  • Patent number: 11441156
    Abstract: The present disclosure relates, according to some embodiments, to pathogen resistant plants, compositions, organisms, systems, and methods. For example, a composition may comprise a heterologous peptide (e.g., a defensin peptide) and/or a nucleic acid (e.g., a defensin nucleic acid). A pathogen resistant plant may comprise, in some embodiments, a heterologous defensin peptide and/or an expressible nucleic acid encoding a heterologous defensin peptide.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: September 13, 2022
    Assignee: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: T. Erik Mirkov, Kranthi Kiran Mandadi
  • Patent number: 11433130
    Abstract: The present disclosure provides a recombinant viral vector comprising at least one transgene inserted into a Marek's disease viral genome for treatment of diseases in poultry. Also provided are immunogenic compositions comprising such recombinant viral vectors and methods for preventing or inhibiting Marek's disease in combination with at least a second disease in poultry.
    Type: Grant
    Filed: October 14, 2020
    Date of Patent: September 6, 2022
    Assignee: The Texas A&M University System
    Inventors: Sanjay M. Reddy, Blanca M. Lupiani
  • Patent number: 11420205
    Abstract: An instrument for energizing molecules contained in a sample solution may include a droplet generator configured to generate droplets of the sample solution. The droplet generator illustratively has an elongated nozzle defining an orifice at one end thereof from which the droplets exit the droplet generator, and the orifice illustratively defines a first longitudinal axis centrally therethrough. A molecule energizing source is configured to produce a molecule energizing field, and is positioned relative to the nozzle orifice such that the molecule energizing field extends into at least some of the generated droplets along a direction non-parallel with the first longitudinal axis. The molecule energizing field illustratively carries energy which heats at least one of the generated droplets sufficiently to induce structural changes in at least one molecule contained in the at least one of the generated droplets.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: August 23, 2022
    Assignees: Indiana University Research and Technology Corp., The Texas A&M University System
    Inventors: David E. Clemmer, Tarik J. El-Baba, Daniel R. Fuller, Daniel W. Woodall, David H. Russell, Evan R. Williams
  • Patent number: 11421225
    Abstract: In an embodiment, a device for modulating intracellular gene expression, the device having a calcium actuator component and a transcription reprogramming component. In another embodiment, a method for modulating intracellular gene expression, where the method includes inducing a system having a calcium actuator component and a transcription reprogramming component with at least one of light and a chemical, causing an increase in Ca2+, and translocating the transcription reprogramming component from cytosol to the nucleus.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: August 23, 2022
    Assignee: The Texas A&M University System
    Inventors: Yubin Zhou, Yun Huang, Nhung T. Nguyen, Lian He
  • Patent number: 11420435
    Abstract: The restretchable stencil frame according to the present invention consists of a metallic stencil foil mounted on a rectangular frame fabricated of tubular material or C-channel. Each corner of the frame is provided with one screw-actuated conical expander and one counterplate serving to biaxially tension the stencil foil. To ensure uniform stretching of the stencil foil, areas of increased elasticity are provided to the corners of the frame and to the foil itself in the form of oriented slots, cuts, holes and combination thereof.
    Type: Grant
    Filed: August 22, 2021
    Date of Patent: August 23, 2022
    Assignee: Texas A&M University Corpus Christi
    Inventor: Petru Aurelian Simionescu
  • Publication number: 20220259585
    Abstract: Embodiments of the present disclosure pertain to methods of constructing a phage display library where at least 90% of combinatorial regions in the phage display library include at least one in-frame amber codon. Further embodiments of the present disclosure pertain to the formed phage display libraries. Additional embodiments of the present disclosure pertain to methods of selecting peptides or proteins that bind to a desired target (e.g., a ligand binding site of a desired target) by utilizing the phage display libraries of the present disclosure. Further embodiments of the present disclosure pertain to peptides that have been screened from the phage display libraries and methods of the present disclosure, such as inhibitors of sirtuin 2, or inhibitors of ENL.
    Type: Application
    Filed: March 4, 2020
    Publication date: August 18, 2022
    Applicant: The Texas A&M University System
    Inventor: Wenshe Liu
  • Publication number: 20220259503
    Abstract: Hydrocarbon conversion and transportation methods and apparatuses are provided. An apparatus may apply electron beam irradiation to hydrocarbons (i.e., natural gas) to convert the hydrocarbons to liquid fuel. Lower-weight hydrocarbons may be converted into medium-weight organics through a gas to liquid process (GTL). The electrons may generate radicals that facilitate desired reactions. The hydrocarbons may be temperature and pressure controlled. For example, the hydrocarbons may be at lower temperatures (e.g., cryogenic or otherwise below ambient) and/or at higher pressures (e.g., greater than standard atmospheric pressures). Temperature suppression may reduce decomposition reactions. A high energy electron beam (e.g., 500 keV or higher, such as 10 MeV) could be used for the conversion process. The hydrocarbon may be liquefied. The liquid-like, higher density lower-weight hydrocarbons may lead to radical-neutral interactions.
    Type: Application
    Filed: July 10, 2020
    Publication date: August 18, 2022
    Applicant: The Texas A&M University System
    Inventors: David Staack, Kunpeng WANG
  • Patent number: 11414556
    Abstract: A biodegradable and biocompatible three dimensional construct comprising a combination of a nano silicate (e.g., laponite) and two different polymers, the two polymers each individually providing at least one covalently linked polymer chain and at least one ionically linked polymer chain, the polymeric chains forming a dual strengthening intertwined polymeric system. The constructs demonstrate improved mechanical and strength properties, while the bioinks provide a material having superior printability characteristics suitable for printing a three dimensional biodegradable construct having an aspect ratio of greater than 2.0. The bioink may also comprise cells or combinations of cells. Methods of using the constructs and bioinks for wound healing preparations and tissue regeneration are also provided.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: August 16, 2022
    Assignee: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Akhilesh K. Gaharwar, David Chimene
  • Publication number: 20220250914
    Abstract: A method of electrochemical exfoliation, may include: electrochemically exfoliating a parent material comprising coke, wherein the electrochemically exfoliating comprises introducing the parent material into a porous chamber, applying pressure to the porous chamber to thereby compress the parent material in the porous chamber, and applying a potential bias to the parent material while at least a portion of the parent material is in contact with an electrolyte solution to produce a mixture of exfoliated material and unexfoliated parent material, wherein the exfoliated material comprises exfoliated graphene; and separating at least a portion of the exfoliated material from the unexfoliated parent material.
    Type: Application
    Filed: January 21, 2022
    Publication date: August 11, 2022
    Applicants: ExxonMobil Chemical Patents Inc., The Texas A&M University System
    Inventors: Rohan Ashok Hule, Micah J. Green, Sanjit Saha, Pritishma Lakhe, Sundararajan Uppili, Sergey Yakovlev
  • Publication number: 20220248616
    Abstract: Disclosed are various embodiments for deep reinforcement learning-based irrigation control to maintain or increase crop yield and/or other desired crop status, and/or reduce water use. One or more computing devices can be configured to determine an amount of water to be applied to at least one crop in at least one of a plurality of irrigation management zones through execution of a deep reinforcement learning routine. Further, the computing devices can determine a start time and an end time to be applied to the at least one of the plurality of irrigation management zones based at least in part on the amount of water determined by the deep reinforcement learning module. Finally, the computing devices can instruct an irrigation system to apply irrigation to the at least one of the plurality of irrigation management zones in accordance with the start time and the end time.
    Type: Application
    Filed: July 8, 2020
    Publication date: August 11, 2022
    Applicant: The Texas A&M University System
    Inventors: Yanxiang YANG, Hongxin KONG, Jiang HU, Dana O. PORTER, Thomas H. MAREK, Kevin R. HEFLIN
  • Publication number: 20220249983
    Abstract: The present disclosure is directed to a new and improved separation process that isolates individual minerals from brines containing a mixture of minerals. The brines may be derived from seawater, brackish water, oilfield brines, solution mining, mine run-off, and other sources. Typically, the minerals are recovered as chlorides using a variety of processing steps including evaporation, centrifugation, elutriation, filtration, electrocogulation, crystallization, adsorption, and chromatography.
    Type: Application
    Filed: September 19, 2021
    Publication date: August 11, 2022
    Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventor: Mark Holtzapple
  • Publication number: 20220252457
    Abstract: A passive infrared (PIR) sensor system, includes a PIR sensor configured to produce an output signal in response to receiving infrared (IR) radiation, an electronic shutter positionable in a field of view (FOV) of the PIR sensor, wherein the electronic shutter includes a liquid crystal (LC) material, wherein the electronic shutter includes a first state providing a first transmissivity of IR radiation through the electronic shutter and a second state providing a second transmissivity of IR radiation through the electronic shutter that is less than the first transmissivity, and a shutter actuator configured to apply an actuation signal to the electronic shutter to actuate the electronic shutter between the first state and the second state.
    Type: Application
    Filed: June 19, 2020
    Publication date: August 11, 2022
    Applicant: The Texas A&M University System
    Inventors: Ya Wang, Libo Wu, Zhangjie Chen
  • Patent number: 11407851
    Abstract: An embodiment includes a system comprising: an iodine containing thermoset open-cell shape memory polymer (SMP) foam that is x-ray visible; wherein (a) the SMP foam is configured to expand from a compressed secondary state to an expanded primary state in response to thermal stimulus, (b) the SMP foam is a poly(urethane-urea-amide). Other embodiments are described herein.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: August 9, 2022
    Assignee: The Texas A&M University System
    Inventors: Landon D. Nash, Kendal P. Ezell