Patents Assigned to The Tructees Of The University Of Pennsylvania
  • METHOD FOR TESTING AND SCREENING P38 MAP KINASE MODIFIERS
    Publication number: 20190071710
    Abstract: This invention provides methods for treating diseases associated with elevated p38 mitogen-activated protein kinase activity. Moreover, the invention provides methods for testing a candidate compound for a p38 mitogen-activated protein kinase modifying activity by calculating the level of relocalization of an SMN complex component from the cytoplasm to the nucleus of a cell. Additionally, the invention provides a kit and a system for calculating the same.
    Type: Application
    Filed: March 26, 2018
    Publication date: March 7, 2019
    Applicant: The Tructees Of The University Of Pennsylvania
    Inventors: Gideon Dreyfuss, Mumtaz Kasim