Abstract: Compounds having the structures below that are TPH1 inhibitors are provided: The compounds are useful of, e.g., to increase bone mass. In preferred embodiments, the patient is known to have, or to be at risk for, a low bone mass disease such as osteoporosis.
Type:
Application
Filed:
November 2, 2010
Publication date:
February 28, 2013
Applicant:
The Trustees of Columbia University in th City of