Abstract: A pre-coelenterazine peptide comprising a modified A. victoria GFP having an amino acid sequence in which Ser.sup.65 is replaced with Tyr. There is further provided a polynucleotide encoding the pre-coelenterazine peptide, allowing synthesis of large, pure amounts of coelenterazine.
Type:
Grant
Filed:
May 26, 1995
Date of Patent:
April 21, 1998
Assignees:
Rutgers, the State University of New Jersey, The Trustees of Columbia University in the City of NY