Patents Assigned to The Trustees of Couumbia University in the City of New York
  • Publication number: 20190015355
    Abstract: The current invention is a method of preventing and treating certain diseases by preventing the synthesis and/or breakdown of glycogen by the administration of an agent, guaiacol. Diseases that can be prevented and treated by the administration of guaiacol include but are not limited to glycogen storage disease type IV (GSD-IV), adult polyglucosan body disease (APBD), and Lafora disease (LD). The invention also includes methods and tools for screening for agents that prevent and treat these diseases as well as basic research, specifically in the form of cells and cell lines that produce detectable polyglucosan.
    Type: Application
    Filed: January 6, 2017
    Publication date: January 17, 2019
    Applicants: The Trustees of Couumbia University in the City of New York, Hadasit Medical Research Services and Development Ltd.
    Inventors: Hasan Orhan AKMAN, Salvatore DIMAURO, Or KAKHLON