Patents Assigned to The Trustees of the Stevens Institute of Technology
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Publication number: 20160375106Abstract: In permeability lung edema, cardiogenic lung edema or neonatal respiratory distress, there is heterogeneous liquid distribution throughout the lungs. The excess alveolar liquid reduces gas exchange. Mechanical ventilation is used to improve gas exchange. In the presence of heterogeneous liquid distribution, there are surface tension-dependent stress concentrations in septa separating aerated from flooded alveoli. Mechanical ventilation, by inflating the lung above normal volumes, thus increasing surface tension above normal, exacerbates the stress concentrations and consequently injures, or exacerbates pre-existing injury of, the alveolar-capillary barrier. Any means of lowering surface tension should lessen ventilation injury of the lung. In the present invention, dilute exogenous surfactant solution or surfactant protein C solution interacts with albumin to lower surface tension, likely through effective promotion of surfactant lipid adsorption.Type: ApplicationFiled: June 27, 2016Publication date: December 29, 2016Applicant: The Trustees of the Stevens Institute of TechnologyInventor: Carrie E. Perlman
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Publication number: 20160367151Abstract: A sensing system includes a sensor including a flexible substrate and a graphene oxide sensing element deposited on the flexible substrate. The graphene oxide sensing element has first and second sides. First and second electrical connectors coupled to the first and second sides of the graphene oxide sensing element, respectively. A power source is coupled to the first and second electrical connectors of the sensor and is adapted to apply a constant voltage to the sensor. The sensing system also includes a measurement element measuring a current in the graphene oxide sensing element due to the constant voltage and a calculation element calculating an electrical resistance of the graphene oxide sensing element based on the electrical current and the constant voltage and calculating a condition at a location of the sensor based on a relationship between the electrical resistance and the condition for the graphene oxide sensing element.Type: ApplicationFiled: June 17, 2016Publication date: December 22, 2016Applicant: THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGYInventors: Linh Tung Le, Trung Thanh Dinh-Trong, Woo Young Lee, Eric Peter Boon, Nguyen An Nguyen
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Patent number: 9504796Abstract: Methods are provided for protecting against ventilation-induced lung injury both directly, by lowering surface tension, and indirectly, by promoting equitable liquid distribution in pulmonary alveolar edema, in which liquid- and air-filled alveoli are normally interspersed. Since a pressure barrier is responsible for trapping liquid in discrete edematous alveoli and the magnitude of the barrier is proportional to surface tension at the air-liquid interface, the present invention provides various methods for promoting equitable redistribution of edema liquid amongst alveoli to help protect the lung during ventilation, including: i) use of an additive that lowers surface tension; ii) use of active, accelerated deflation during mechanical ventilation; and iii) high frequency (>50 Hz) vibration of the lung.Type: GrantFiled: October 12, 2012Date of Patent: November 29, 2016Assignee: THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGYInventor: Carrie E. Perlman
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Publication number: 20160298253Abstract: A method for fabricating a sensor includes coating an end-polished sapphire fiber with aluminum to produce a sapphire fiber having an aluminum coating, anodizing the aluminum coating to produce an aluminum oxide coating, and removing the aluminum oxide coating from a distal end of the sapphire fiber.Type: ApplicationFiled: April 7, 2015Publication date: October 13, 2016Applicant: The Trustees of the Stevens Institute of TechnologyInventors: Henry Du, Hui Chen, Fei Tian
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Patent number: 9458568Abstract: A method for fabricating a patterned fibrous matrix includes providing a printer adapted to use an etching solvent as an ink; providing to the printer a fibrous matrix to use as a printing medium; providing to the printer a pattern for printing on the fibrous matrix; printing by the printer the pattern on the fibrous matrix; and receiving from the printer the patterned fibrous matrix with the pattern etched thereon.Type: GrantFiled: May 22, 2015Date of Patent: October 4, 2016Assignee: The Trustees of the Stevens Institute of TechnologyInventors: Chao Jia, Hongjun Wang
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Publication number: 20160277529Abstract: A system includes a device that is disposed within an environment and is adapted to communicate over a radio frequency communication link. The system also includes a wireless access point disposed within the environment, including a wireless transceiver in communication with the device over a radio frequency communication link using a plurality of channels, and recording a channel state information data set for the radio frequency communication link. The system also includes a monitoring device including a memory storing a plurality of activity profiles, each of which includes an activity and a channel state information profile corresponding to the activity, and a processor receiving, from the wireless access point, the channel state information data set and determining, based on a comparison of the channel state information data set to the channel state information profile of each of the plurality of activity profiles, the activity of the person in the environment.Type: ApplicationFiled: March 18, 2016Publication date: September 22, 2016Applicant: THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGYInventors: Yingying Chen, Jie Yang, Yan Wang, Jian Liu, Marco Gruteser
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Patent number: 9437893Abstract: An in-membrane micro fuel cell comprises an electrically-insulating membrane that is permissive to the flow of cations, such as protons, and a pair of electrodes deposited on channels formed in the membrane. The channels are arranged as conduits for fluids, and define a membrane ridge between the channels. The electrodes are porous and include catalysts for promoting the liberation of a proton and an electron from a chemical species and/or or the recombination of a proton and an electron with a chemical specie. The fuel cell may be provided a biosensor, an electrochemical sensor, a microfluidic device, or other microscale devices fabricated in the fuel cell membrane.Type: GrantFiled: August 28, 2014Date of Patent: September 6, 2016Assignee: The Trustees of the Stevens Institute of TechnologyInventors: Ayokunle Omosebi, Ronald Besser
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Patent number: 9399580Abstract: Granules of graphene oxide may be produced from a dispersion of nanoscale graphene oxide sheets by a spray drying method. Such granules have a three-dimensional corrugated morphology. The complexity of the corrugations, and the size distribution of the granules can be varied through selection of the spray-drying equipment used, and variation of the composition of the dispersion and the spray-drying parameters. Structural modifiers may be included in the graphene oxide dispersion to control the ultimate morphology of the granules. The granules of graphene oxide may be thermally reduced at a moderate temperature of 220° C. to increase the granules' electrical conductivity. The reduced granules may be used to fabricate electrodes for supercapacitors. The power and energy density of such an electrode material is comparable to those of conventional/commercial activated carbon-based electrodes.Type: GrantFiled: September 25, 2015Date of Patent: July 26, 2016Assignee: The Trustees of the Stevens Institute of TechnologyInventors: Hongwei Qiu, Thomas A. Bechtold, Lihn Tung Le, Woo Young Lee
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Publication number: 20160212163Abstract: A system and method of detecting a source of a rumor in a social media network is disclosed. The social media network includes a plurality of node clusters, each of the plurality of nodes therein having at least one edge connection to a corresponding number of different nodes in the same cluster. The system identifies a plurality of gateway nodes, each having at least one weak tie connection with a corresponding gateway node from a different node cluster; selects a subset of gateway nodes as sensors to measure arrival times of a rumor; and selects a candidate node cluster based on these arrival times. From there, the system selects a set of nodes in the candidate cluster to measure arrival times of a rumor from a source node, and selects a candidate node from the candidate cluster as having a high probability of being the source node.Type: ApplicationFiled: January 19, 2016Publication date: July 21, 2016Applicant: The Trustees of The Stevens Institute of TechnologyInventors: Alireza Louni, Koduvayur Parthasarathy Subbalakshmi
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Patent number: 9398268Abstract: A method and system for cooperative diversity visual cognition in a wireless sensor network is disclosed. The method and system are capable of solving distributed visual cognition tasks (for example, online simultaneous reconstruction of 3D models of a large area) by using multiple video streams and exploiting cooperative diversity video sensing information while ensuring an optimal tradeoff between energy consumption and video quality of images received from said multiple video streams.Type: GrantFiled: May 24, 2012Date of Patent: July 19, 2016Assignees: Siemens Corporation, Siemens Aktiengesellschaft Osterreich, The Trustees of the Stevens Institute of TechnologyInventors: Maneesh Kumar Singh, Cristina Comaniciu, Dorin Comaniciu, Stefan Kluckner
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Publication number: 20160115535Abstract: A device for detecting biospecific oligonucleotides includes a plurality of microgel spots, each of which is functionalized with molecular beacon probes and amplification primers tethered thereto. Each of the respective probes is arranged to bind to an antisense counterpart of one type of biospecific oligonucleotide. The various microgels may each be functionalized for a different oligonucleotide. In a system that incorporates the aforesaid device, the device is in contact with a solution that includes a system of molecules that cooperated with the tethered probes and primers to capture, amplify, and detect the antisense counterparts of one or more biospecific oligonucleotides. In one such system, the enzymes and primers are arranged to implement a NASBA amplification process operating on the biospecific oligonucleotides.Type: ApplicationFiled: January 26, 2015Publication date: April 28, 2016Applicant: The Trustees Of The Stevens Institute Of TechnologyInventors: Xiaoguang Dai, Youlong Ma, Matthew Libera
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Publication number: 20160114873Abstract: A system designed as a benign disablement weapon for use against sailboats and a method for using the system. The system may be easily deployed to stop sailboats by disabling the propeller. The system uses a buoyant component that floats covertly on the water surface and to which many entanglement lines are attached. Upon the targeted boat passing over the system, the buoyant interface catches on the keel of the vessel. The buoyant interface then drags the entanglement lines with the vessel which puts the lines in position to catch on the propeller, causing the vessel to become disabled. The system may be modified for use in disabling motor craft.Type: ApplicationFiled: August 10, 2015Publication date: April 28, 2016Applicant: THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGYInventors: Paul D. Mascia, Mark Mallett, John C. vanRoden, Jonathan Samuel, Ryan T. Britt, Michael Francis DeLorme
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Patent number: 9321030Abstract: A film for the retention and controlled release of organic or inorganic molecules consists essentially of a phyllosilicate clay and a organic polyanion. The film may be a built-up layered film of alternating layers of the clay and the polyanion. Organic or inorganic molecules are absorbed into the film from solution, and released in response to changes in the film's environment. The film may be built up using layer-by-layer (LbL) methods, or deposited on a substrate from a mixture of the clay and polyanion. Articles may be coated with the film by the same methods. The film is useful for the controlled release of antibiotics in response to infections, and also retains antibiotics such that bacteria may be killed by direct contact with the film.Type: GrantFiled: December 18, 2012Date of Patent: April 26, 2016Assignee: The Trustees of the Stevens Institute of TechnologyInventors: Svetlana Sukhishvili, Svetlana Pavlukhina
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Patent number: 9322646Abstract: A method of adaptively positioning a scanner [10] within a three-dimensional scene identifies an optimal next position for the scanner [40] based on analysis of a data point cloud that mimics the scanned portion of the scene. Occluded areas [38] are delineated from scan data and scans made at different locations in the scene are registered to a reference four-coordinate system. The fourth coordinate corresponds to the hue observed by the scanner at each data point.Type: GrantFiled: April 8, 2011Date of Patent: April 26, 2016Assignee: The Trustees of the Stevens Institute of TechnologyInventors: Kishore V. Pochiraju, Hao Men, Biruk Assefa Gebre
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Patent number: 9292493Abstract: An apparatus and method for determining whether text is deceptive has a computer programmed with software that automatically analyzes text in digital form by at least one of statistical analysis of psycho-linguistic cues, IP geo-location, gender analysis, authorship analysis, and analysis to detect coded/camouflaged messages. The computer has truth data against which the text message can be compared and a graphical user interface. The computer may be connectable to the Internet and may obtain the text automatically. Speech-to-text software may be used to convert verbal messages to text for analysis. The system may be made available on a webpage, web service, on a computer or by a wireless device. The text may be emails, website content, tweets. In one embodiment, the system detects coded messages.Type: GrantFiled: April 26, 2011Date of Patent: March 22, 2016Assignee: The Trustees of The Stevens Institute of TechnologyInventors: Rajarathnam Chandramouli, Xiaoling Chen, Koduvayur P. Subbalakshmi, Rohan Perera
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Publication number: 20160067210Abstract: Rhodamine dye is delivered to regions of a lung having heterogeneous alveolar flooding by alveolar liquid, thereby lowering the surface tension of the alveolar liquid so as to lessen ventilation injury directly and, by promoting equitable redistribution of the alveolar liquid among the alveoli of the lung, indirectly. The rhodamine dye is delivered with an albumin and/or an exogenous surfactant. Exemplary rhodamine dyes include sulforhodamine B and rhodamine WT.Type: ApplicationFiled: November 13, 2015Publication date: March 10, 2016Applicant: THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGYInventor: Carrie E. Perlman
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Patent number: 9267938Abstract: The described invention provides an ex vivo dynamic multiple myeloma (MM) cancer niche contained in a microfluidic device. The dynamic MM cancer niche includes (a) a three-dimensional tissue construct containing a dynamic ex vivo bone marrow (BM) niche, which contains a mineralized bone-like tissue containing viable osteoblasts self-organized into cohesive multiple cell layers and an extracellular matrix secreted by the viable adherent osteoblasts; and a microenvironment dynamically perfused by nutrients and dissolved gas molecules; and (b) human myeloma cells seeded from a biospecimen composition comprising mononuclear cells and the multiple myeloma cells. The human myeloma cells are in contact with osteoblasts of the BM niche, and the viability of the human myeloma cells is maintained by the MM cancer niche.Type: GrantFiled: March 14, 2013Date of Patent: February 23, 2016Assignees: The Trustees of the Stevens Institute of Technology, Hackensack University Medical CenterInventors: Woo Lee, Jenny Zilberberg, David Samuel Siegel, Peter Tolias, Hongjun Wang, Wenting Zhang
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Publication number: 20160016802Abstract: Granules of graphene oxide may be produced from a dispersion of nanoscale graphene oxide sheets by a spray drying method. Such granules have a three-dimensional corrugated morphology. The complexity of the corrugations, and the s size distribution of the granules can be varied through selection of the spray-drying equipment used, and variation of the composition of the dispersion and the spray-drying parameters. Structural modifiers may be included in the graphene oxide dispersion to control the ultimate morphology of the granules. The granules of graphene oxide may be thermally reduced at a moderate temperature of 220° C. to increase the granules' electrical conductivity. The reduced granules may be used to fabricate electrodes for supercapacitors. The power and energy density of such an electrode material is comparable to those of conventional/commercial activated carbon-based electrodes.Type: ApplicationFiled: September 25, 2015Publication date: January 21, 2016Applicant: THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGYInventors: Hongwei Qiu, Thomas A. Bechtold, Linh Tung Le, Woo Young Lee
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Publication number: 20150368585Abstract: A method for converting a biomass to a bio-oil includes providing a four-stroke internal combustion engine having at least one cylinder, at least one piston, and a crankshaft coupled to each of the at least one piston. The method also includes coupling a power source to the crankshaft in a manner such that the power source drives rotation of the crankshaft. The method also includes injecting a first mixture including a biomass and a non-oxidizing compression gas into one of the cylinders. The method also includes compressing and heating the first mixture during a compression stroke of the pistons. The compression and heating of the first mixture pyrolizes the biomass to produce a second mixture including a bio-oil and the compression gas. The method also includes decompressing and cooling the second mixture during an expansion stroke of the pistons. The decompression and cooling of the second mixture quenches secondary pyrolysis.Type: ApplicationFiled: June 17, 2015Publication date: December 24, 2015Applicant: THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGYInventor: Nicholaus Joseph Parziale
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Publication number: 20150337489Abstract: A method for fabricating a patterned fibrous matrix includes providing a printer adapted to use an etching solvent as an ink; providing to the printer a fibrous matrix to use as a printing medium; providing to the printer a pattern for printing on the fibrous matrix; printing by the printer the pattern on the fibrous matrix; and receiving from the printer the patterned fibrous matrix with the pattern etched thereon.Type: ApplicationFiled: May 22, 2015Publication date: November 26, 2015Applicant: The Trustees of the Stevens Institute of TechnologyInventors: Chao Jia, Hongjun Wang