Patents Assigned to The Trustees of the Univ. of Penna.
  • Propargylic and allenic sulfones
    Patent number: 5237101
    Abstract: Propargylic and allenic sulfones are disclosed having the ability to selectively cleave nucleic acids, especially deoxyribonucleic acid. Such compositions are capable of being synthetically modified to effect cleavage at selected, sequenced sites on nucleic acids.
    Type: Grant
    Filed: January 26, 1990
    Date of Patent: August 17, 1993
    Assignee: The Trustees of the Univ. of Penna.
    Inventors: K. C. Nicolaou, Guido Zaccarello, Golfo Skokotas, Peter Maligres