Abstract: A recombinant vector comprising capsid proteins derived from simian adenovirus Pan5, Pan6, Pan7, SV1, SV25 or SV39 sequences are described. These vectors contain a heterologous gene under the control of regulatory sequences packaged in the capsid. A cell line which expresses simian adenovirus gene(s) is also disclosed. Methods of using the vectors and cell lines are provided.
Type:
Grant
Filed:
November 20, 2002
Date of Patent:
July 24, 2007
Assignee:
The Trustees of the University of Pennsylavania
Inventors:
James M. Wilson, Guangping Gao, Soumitra Roy
Abstract: Electron-deficient porphyrins are provided, as well as processes and intermediates for their preparation. In preferred embodiments, the electron-deficient porphyrins are prepared by condensing pyrrole derivatives and removing water thus formed from the resulting reaction mixture.
Type:
Grant
Filed:
August 5, 1998
Date of Patent:
August 8, 2000
Assignee:
The Trustees of the University of Pennsylavania