Abstract: Monodisperse particles having: a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology are disclosed. Due to their uniform size and shape, the monodisperse particles self assemble into superlattices. The particles may be luminescent particles such as down-converting phosphor particles and up-converting phosphors. The monodisperse particles of the invention have a rare earth-containing lattice which in one embodiment may be an yttrium-containing lattice or in another may be a lanthanide-containing lattice. The monodisperse particles may have different optical properties based on their composition, their size, and/or their morphology (or shape).
Type:
Grant
Filed:
August 16, 2017
Date of Patent:
September 4, 2018
Assignees:
Intelligent Material Solutions, Inc., The Trustees of the University of Pennsylvannia
Inventors:
Joshua E. Collins, Howard Y. Bell, Xingchen Ye, Christopher Bruce Murray
Abstract: This invention is directed to compositions for promoting wound healing and regeneration and methods of use thereof. In one aspect, methods for promoting wound healing in a subject are provided, the methods comprising: administering a therapeutically effective amount of a DNA methyl transferase inhibitors (DNMT) to the subject. In another aspect, methods for reducing scarring during healing of a skin wound are provided, the methods comprising: administering a therapeutically effective amount of a DNMT inhibitor.
Type:
Application
Filed:
July 21, 2015
Publication date:
July 27, 2017
Applicant:
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANNIA
Inventors:
George COTSARELIS, Jen-Chih HSIEH, Ying ZHENG