Patents Assigned to THE TRUSTEES OF THE UNIVERSITY OF PHILADELPHIA
  • Publication number: 20240082361
    Abstract: This invention relates to methods of treating and ameliorating congenital and neonatal hyperinsulinism and post-prandial hypoglycemia, comprising the step of administering an antagonist of the Glucagon-Like Peptide-1 (GLP-1) receptor, e.g. a GLP-1 fragment or analogue thereof.
    Type: Application
    Filed: February 14, 2023
    Publication date: March 14, 2024
    Applicants: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, The Children's Hospital of Philadelphia
    Inventors: Doris STOFFERS, Diva D. DE LEON, Charles STANLEY
  • Patent number: 10166276
    Abstract: The present invention provides recombinant peptides comprising a B cell receptor (BCR) or a fragment thereof, nucleotide molecules encoding same, and vaccines and vectors comprising same; and methods of treating, inducing an immune response against, inducing a regression of, and suppressing a formation of a lymphoma, comprising administering same. The present invention also provides methods of inducing a humoral immune response in an animal against an antigen, comprising administering to the animal a fusion peptide comprising an LLO protein or fragment thereof fused to the antigen.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: January 1, 2019
    Assignee: The Trustees of the University of Philadelphia
    Inventors: Yvonne Paterson, Paul Neeson
  • Patent number: 9758724
    Abstract: Monodisperse particles having: a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology are disclosed. Due to their uniform size and shape, the monodisperse particles self assemble into superlattices. The particles may be luminescent particles such as down-converting phosphor particles and up-converting phosphors. The monodisperse particles of the invention have a rare earth-containing lattice which in one embodiment may be an yttrium-containing lattice or in another may be a lanthanide-containing lattice. The monodisperse particles may have different optical properties based on their composition, their size, and/or their morphology (or shape).
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: September 12, 2017
    Assignees: INTELLIGENT MATERIAL SOLUTIONS, INC., THE TRUSTEES OF THE UNIVERSITY OF PHILADELPHIA
    Inventors: Joshua E. Collins, Howard Y. Bell, Xingchen Ye, Christopher Bruce Murray