Patents Assigned to The Trustees of the Universiy of Pennsylvania
  • Methods and compositions for inhibiting delayed graft function
    Patent number: 9950038
    Abstract: Disclosed are compositions and methods for inhibiting preventing, reducing delayed graft function, allograft rejection or ischemia reperfusion injury.
    Type: Grant
    Filed: February 8, 2012
    Date of Patent: April 24, 2018
    Assignee: THE TRUSTEES OF THE UNIVERSIY OF PENNSYLVANIA
    Inventor: Richard P. Shannon
  • Endometriosis mouse model
    Patent number: 6429353
    Abstract: The invention provides an endometriosis mouse model wherein severely compromised immune deficient (SCID) female mice are transplanted with human xenografts of normal endometrial tissue, but result in mice with human endometriosis. Typically, the xenografts are treated with a micronized estrogen source prior to transplantation or implantation and the endogenous progesterone of the mice is eliminated also prior to transplantation of the human xenograft. These diseased mice are useful in the study of endometriosis.
    Type: Grant
    Filed: March 25, 1998
    Date of Patent: August 6, 2002
    Assignees: Reprogen, Inc., The Trustees of the Universiy of Pennsylvania
    Inventors: Jeffrey Boyd, Jerome J. Strauss, Peter Van Deerlin, Karen K. Yamamoto