Abstract: Sequences of novel adeno-associated virus capsids and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles. AAV-mediated delivery of therapeutic and immunogenic genes using the vectors of the invention is also provided.
Type:
Application
Filed:
September 30, 2004
Publication date:
February 15, 2007
Applicant:
The Trutees of the University of Pennsylvania
Inventors:
James Wilson, Guangping Gao, Mauricio Alvira, Luc Vandenberghe