Patents Assigned to The United Sates of America as represented by the Secretary of Agriculture
  • Patent number: 10450364
    Abstract: In one aspect, the present invention is directed to a method for preventing or treating necrotic enteritis by administering a hyperimmunized egg product obtained from an egg-producing animal to an avian. The hyperimmunized egg product may contain an antibody specific to an antigen selected from the group consisting of Clostridium perfringens ?-toxin, Clostridium perfringens elongation factor Tu (EF-Tu), Clostridium perfringens necrotic enteritis B-like (NetB) toxin, Clostridium perfringens Pyruvate: Ferredoxin oxidoreductase (PFO), and Eimeria tenella elongation factor 1-alpha.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: October 22, 2019
    Assignees: Arkion Life Sciences, LLC, United Sates of America, as Represented by the Secretary of Agriculture
    Inventors: Hyun S. Lillehoj, Earnest W. Porta, Samuel V. Walker, Leslie A. Confer, Ujvala Deepthi Gadde, Cyril Gay
  • Publication number: 20140302004
    Abstract: Multi-drug resistant superbugs are a persistent problem in modern health care. This invention provides an antimicrobial endolysin-Lysostaphin triple fusion protein, comprising (1) an endolysin CHAP endopeptidase domain, (2) an endolysin amidase domain, and (3) a Lysostaphin glycyl-glycine endopeptidase domain. The domains are derived from two proteins that show antimicrobial synergy when used in combination. The protein has specificity and exolytic activity for the peptidoglycan cell wall of untreated, live Staphylococcus aureus from many growth phases i.e. stationary, logarithmic and biofilm growth. The recombinant triple fusion protein comprising the three functional antimicrobial domains is designed to be refractory to resistance development.
    Type: Application
    Filed: March 18, 2013
    Publication date: October 9, 2014
    Applicant: The United Sates of America, as represented by the Secretary of Agriculture
    Inventor: The United Sates of America, as represented by the Secretary of Agriculture
  • Patent number: 3983067
    Abstract: Acetal derivatives of polyunsaturated fatty compositions were prepared and found to function as primary plasticizers. Poly(vinyl chloride) resins plasticized by the compositions of the invention have properties equal or superior to resins plasticized by dioctyl phthalate or dioctyl sebacate.
    Type: Grant
    Filed: July 1, 1974
    Date of Patent: September 28, 1976
    Assignee: The United Sates of America as represented by the Secretary of Agriculture
    Inventors: Richard A. Awl, Everett H. Pryde