Patents Assigned to The United Stated of America, as represented by the Secretary, Departmnet of Health and Human Servic
  • METHODS FOR DECREASING INFLUENZA-INDUCED LETHALITY USING GASTRIN-RELEASING PEPTIDE (GRP) INHIBITORS OR GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) ANTAGONISTS
    Publication number: 20220002399
    Abstract: Gastrin-releasing peptide (GRP) is a neuroendocrine peptide that acts as a novel contributor to the inflammatory response to influenza infection. Thus, inhibition of GRP or antagonizing the GRP receptor (GRPR) during influenza infection represents a novel therapeutic approach to mitigating lung damage. The present invention encompasses methods of treatment based on these novel findings and observations.
    Type: Application
    Filed: September 10, 2019
    Publication date: January 6, 2022
    Applicants: University of Maryland, Baltimore, The United Stated of America, as represented by the Secretary, Departmnet of Health and Human Servic
    Inventors: Stefanie N VOGEL, Kari Ann SHIREY, Frank CUTTITTA