Patents Assigned to THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OE VETERANS AFFAIRS
  • Genetically induced nephron progenitors
    Patent number: 11492644
    Abstract: Expression of exogenous SNAI2, EYA1 and SIX1 genes in a cell, tissue or organ not normally having nephron progenitor activity, induces or re-programs that cell to have or subsequently develop nephron progenitor activity. Nephron progenitors induced 5 by expression of SNAI2, EYA1 and SIX1 may be used for the production of nephron cells and tissues that are useful in treatment of kidney disorders, kidney regeneration, kidney transplantation, bioprinting and nephrotoxocity testing.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: November 8, 2022
    Assignees: MURDOCH CHILDRENS RESEARCH INSTITUTE, VANDERBILT UNIVERSITY, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OE VETERANS AFFAIRS
    Inventors: Melissa Little, Jessica Vanslambrouck, Lauren Woodard, Matthew Wilson