Patents Assigned to The United States of America, as rep. by the Sec'y of the Army, for U.S. Army Medical Research Insti
  • SIN NOMBRE VIRUS FULL-LENGTH M SEGMENT-BASED DNA VACCINES
    Publication number: 20160346376
    Abstract: The invention contemplates a new synthetic, codon-optimized Sin Nombre virus (SNV) full-length M gene open reading frame (ORF) that encodes a unique consensus amino acid sequence. The SNV ORF was cloned into a plasmid to form the first stable recombinant SNV full-length M gene that elicits neutralizing antibodies. The gene can be engineered into a vaccine system, and is useful to protect mammals against infection with Sin Nombre virus.
    Type: Application
    Filed: March 25, 2016
    Publication date: December 1, 2016
    Applicant: The United States of America, as rep. by the Sec'y of the Army, for U.S. Army Medical Research Insti
    Inventor: JAY HOOPER