Patents Assigned to The United States of America as rep. by the Sec'y of the Army, for U.S. Army Medical Research Institute of Infectious Diseases
  • Nucleic acids containing a synthetic codon-optimized Sin Nombre virus full-length M gene
    Patent number: 9315826
    Abstract: The invention contemplates a new synthetic, codon-optimized Sin Nombre virus (SNV) full-length M gene open reading frame (ORF) that encodes a unique consensus amino acid sequence. The SNV ORF was cloned into a plasmid to form the first stable recombinant SNV full-length M gene that elicits neutralizing antibodies. The gene can be engineered into a vaccine system, and is useful to protect mammals against infection with Sin Nombre virus.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: April 19, 2016
    Assignee: The United States of America as rep. by the Sec'y of the Army, for U.S. Army Medical Research Institute of Infectious Diseases
    Inventor: Jay Hooper