Abstract: Disclosed is a molecule comprising: (a) a first domain, which comprises a targeting moiety; (b) a second domain, which comprises an albumin binding domain (ABD), (c) a third domain, which comprises a furin cleavage sequence (“FCS”), which FCS is cleavable by furin; and (d) a fourth domain, which comprises an optionally substituted Domain III from Pseudomonas exotoxin A (“PE”). Related nucleic acids, recombinant expression vectors, host cells, populations of cells, pharmaceutical compositions, methods of producing the molecule, methods of treating or preventing cancer in a mammal, and methods of inhibiting the growth of a target cell are also disclosed.

Abstract: A method for growing nanocrystalline diamond (NCD) on Ga2O3 to provide thermal management in Ga2O3-based devices. A protective SiNx interlayer is deposited on the Ga2O3 before growth of the NCD layer to protect the Ga2O3 from damage caused during growth of the NCD layer. The presence of the NCD provides thermal management and enables improved performance of the Ga2O3-based device.

Abstract: Systems and methods for independently managing wireless transmission by individual spectrum access systems in a radio frequency spectrum shared by a plurality of spectrum access systems. An example method includes: receiving, by the spectrum access system, an interference budget from a sensor; determining, by the spectrum access system, secondary users managed by the spectrum access system in a radio frequency spectrum shared by a plurality of spectrum access systems; managing a move list for the spectrum access system independently of the other spectrum access systems in an absence of exchange of spectrum grant information with the other spectrum access systems; and determining the move list for the spectrum access system from a first moment and a second moment of an aggregate interference distribution such that the spectrum access system provides grants to its secondary users in a dynamic protection area of the spectrum access system.

Abstract: Provided is a tool for providing long distance shooters with the ability to receive information from others in the field to adjust their weapon system for the best advantage based on distance, location, and range. The tool may implemented as an application on a mobile device such as a smart phone, for example, making the tool light weight, space efficient, and portable for use in the field. The communication ability allows for tracking shooting partners as well as on-the-spot coordination. The tool further provides range markings, yard lines, and topographic data that allow the shooter to make decisions based on real time data. Shooters are therefore afforded a tool that is portable, easy to use, and flexible enough to use in high-pressure environments.

Abstract: A system for generating a privacy protected image. The system may have a detection logic and obscuring logic configured to detect one or more identity-correlated object categories. The system may provide automatic selection of a type of obscuring to be used based on the detected category; wherein said automatic selection includes automatically selecting among a plurality of different, category specific types of reversible obscuring. The detection logic and obscuring logic may include an automatic category-specific selecting between irreversible obscuring and reversible obscuring. The system may comprise a privacy protected image output logic configured to generate the privacy protected image.

Abstract: Coronavirus S ectodomain trimers stabilized in a prefusion conformation, nucleic acid molecules and vectors encoding these proteins, and methods of their use and production are disclosed. In several embodiments, the coronavirus S ectodomain trimers and/or nucleic acid molecules can be used to generate an immune response to coronavirus in a subject. In additional embodiments, the therapeutically effective amount of the coronavirus S ectodomain trimers and/or nucleic acid molecules can be administered to a subject in a method of treating or preventing coronavirus infection.

Abstract: A method of determining the location of an object in a camera field of view is disclosed. The method may utilize a camera system that includes a digital video camera and a computer that runs image analysis software for analyzing images received from the camera. The image analysis software is configured to isolate pixel groups in each image. The method includes the steps of locating an object in the camera's field of view in which the object is represented by a set of pixels; identifying the centroid of the set of pixels representing the object; and calculating the location of the object relative to the camera based upon known parameters including the focal plane and camera lens location.

Abstract: A projector includes a beam homogenizer receiving light from a light source and creating a predetermined illumination, and a spatial light modulator including grating stages to receive the predetermined illumination. Each grating stage may include a plurality of pixels where corresponding pixels in the grating stages are aligned with one another. Each of the pixels may include a liquid crystal layer disposed between two substrates, where a pixel is switchable by applying a voltage thereto, with a grating period of the pixel selected such that, when the voltage is applied to the pixel and light is passed therethrough, optical energy from the light in plus and minus first orders is deflected toward sides of the pixel and optical energy from a zero order of the light is allowed to pass through the pixel, with a polarization state of the light maintained through the pixel.

Abstract: An in-situ method for changing surface features of a metal workpiece. An electrically conductive workpiece is immersed in a bath containing an electrolyte solution devoid of ions corresponding to the workpiece. A counter electrode is immersed in the bath. An electric power supply is connected to the workpiece and the counter electrode. An electric current is passed in a first direction between the workpiece and the counter electrode, while the workpiece serves as an anode. The electric current polarity is reversed to pass the electric current in a second direction between the metallic workpiece and the electrode, while the workpiece serves as a cathode. The electric current polarity in the first direction drives ions from the workpiece into the electrolyte solution, and the electric current polarity in the second direction plates the ions onto the workpiece in the same bath.

Abstract: An electromagnetic signal detector includes a photonic crystal substrate, an antenna disposed on the substrate and having an active feed region and a ground region spaced apart from one another by a gap, a photonic crystal disposed on the substrate at the gap, and an electro optic polymer disposed on the photonic crystal.

Abstract: Disclosed are methods of isolating paired T cell receptor (TCR) alpha and beta chain sequences, or an antigen-binding portion thereof. Also disclosed are methods of automatically identifying the TCR alpha and beta chain V segment sequences and CDR3 sequences of a TCR having antigenic specificity for a mutated amino acid sequence encoded by a cancer-specific mutation. Methods of preparing a population of cells that express paired TCR alpha and beta chain sequences, or an antigen-binding portion thereof, are also disclosed. Isolated pairs of TCR alpha and beta chain sequences and isolated populations of cells prepared by the methods are also disclosed.

Abstract: A media holder can be used for preparing samples. The media holder can comprise a base, a pair of walls extending upwardly from the base, and a plurality of transverse members positioned on and coupled to a respective upper end of each of the walls. Each of the transverse members can define a receiving slot for receiving at least a portion of a media therein.

Abstract: Disclosed is a thermal desorber assembly for desorbing substances collected on a high-volume sampling (HVS) filter. The assembly includes, among other elements, a filter holder for securing a HVS filter within the assembly, a desorber body, and an insulating enclosure. The design of the thermal desorber assembly is such that it can accommodate a variety of different types of HVS filter media. Also described herein is a system comprising the thermal desorber assembly and method of using the assembly.

Abstract: Provided herein are methods of reducing or eliminating undifferentiated pluripotent stem cells, where the methods comprise contacting an effective amount of a compound to a heterogeneous cell population or sample comprising or suspected of comprising differentiated cell types and undifferentiated pluripotent stem cells, whereby the contacting selectively reduces or eliminates undifferentiated pluripotent stem cells from the cell population or sample. Also provided are methods for obtaining a population of stem cell-derived cell types substantially free of undifferentiated pluripotent stem cells as well as isolated populations of such of stem cell-derived cell types.

Abstract: A recoilless gun system, comprising a gun assembly and associated ammunition for use with the gun assembly employs an integral barrel and a rear inserted ammunition round. The recoilless gun system may combine a laser initiator and a polymer cased ammunition to enable a lightweight system. In such embodiments, the cartridge case is made from a polymer that resists high pressure before extruding into small gaps.

Abstract: Various embodiments are directed to systems, apparatus and methods configured for anthropometrics data/measurement acquisition such as for fitment of handguns, hand tools, weapons and the like.

Abstract: Disclosed are methods and systems of providing carbon nanotubes decorated with polymer coated metal nanoparticles. Then, annealing the metal coated carbon nanotubes to reduce a quantity of hydrophilic components of the polymer coating.

Abstract: Benzoxazine compounds, methods of making them, polymers made therefrom and methods of polymerizing the benzoxazines. These renewable benzoxazine monomers and polymers that utilize the variety of building blocks found in renewable plant biomass, demonstrate excellent processability and large temperature windows for processing of resin systems.

Abstract: The embodiments include an array in intimate adjacent contact with a substrate foundation. The array has a plurality of radio frequency (RF) witness films overlain on the substrate foundation. Each RF witness film is a unit cell defined in a three-dimensional coordinate frame of reference, and is centered at an origin of the three-dimensional coordinate frame of reference. Each RF witness film in the plurality of RF witness films is equally-spaced from adjacent RF witness films.