Patents Assigned to The United States of America as represented by the Deparmtent of Health and Human Services
  • Immortalized and malignant human prostatic cell lines
    Patent number: 5824488
    Abstract: Immortalized malignant human prostatic epithelial and fibroblast cell lines are described containing DNA of a human papillomavirus (HPV) and similar cell lines containing DNA of a human papillomavirus and an activated viral ras oncogene, such as v-Ki-ras. The cell lines are useful for research on drugs for treatment of prostatic cancer and other diseases. The cell lines are useful for research on causes, treatment and prevention of prostate cancer, benign prostatic hyperplasia, male infertility, birth defects, aging and assessment of environmental toxic agents.
    Type: Grant
    Filed: April 28, 1994
    Date of Patent: October 20, 1998
    Assignees: Board of Trustees operating Michigan State University, The United States of America as represented by the Deparmtent of Health and Human Services
    Inventors: Mukta M. Webber, Johng S. Rhim