Abstract: A method for concentrating a solute from a mixture by countercurrent chromatography, by introducing a stationary phase into a countercurrent chromatographic centrifuge, introducing a sample of a mixture containing a solute into the centrifuge, introducing a sufficient quantity of an elution peak sharpening agent into the centrifuge, introducing a mobile phase into the centrifuge, and performing countercurrent chromatographic centrifugation. The eluting fractions containing the concentrated solute are identified and collected.
Type:
Grant
Filed:
September 20, 1993
Date of Patent:
October 11, 1994
Assignee:
The United States of America as represented by the Departent of Health and Human Services