Patents Assigned to The United States of America as represented by the Department of Veterans Affairs, Office of the General Counsel (024)
  • Treatment of disease by inducing cell apoptosis
    Patent number: 7402567
    Abstract: The present invention relates generally to the treatment and prevention of diseases characterized by excess cell proliferation and/or activation. In particular, the present invention provides compositions and methods to suppress the activation and/or proliferation of various cells. In preferred embodiments, the present invention provides compositions and methods to suppress the activation and/or proliferation of mesenchymally derived cells (including, but not limited to hepatic stellate cells), as well as cells with abnormal growth characteristics. In particularly preferred embodiments, the present invention provides compositions and methods to induce fibrosis.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: July 22, 2008
    Assignees: The Regents of the University of California, The United States of America as represented by the Department of Veterans Affairs, Office of the General Counsel (024)
    Inventors: Mario Chojkier, Martina Buck