Patents Assigned to The United States of America as represented by the Dept. of Health and Human Services (DHHS)
  • Rotavirus antigens
    Patent number: 8685411
    Abstract: The present invention relates to novel recombinant polypeptide antigens that may comprise subunit vaccines against rotavirus infection. Further, the present invention relates to methods for use of said antigens in the diagnosis, treatment and prevention of rotavirus infection.
    Type: Grant
    Filed: January 3, 2007
    Date of Patent: April 1, 2014
    Assignees: Children's Medical Center Corporation, The Board of Trustees of the Leland Stanford Junior University, The United States of America as represented by the National Institutes of Health (NIH), The United States of America as represented by the Dept. of Health and Human Services (DHHS)
    Inventors: Philip R. Dormitzer, Stephen C. Harrison, Harry B. Greenberg, Joshua Yoder
  • Method of manufacturing electric device, array of electric devices, and manufacturing method therefor
    Patent number: 8679984
    Abstract: An example embodiment relates to a method of manufacturing an array of electric devices that includes attaching a platform including a micro-channel structure to a substrate. The method includes injecting first and second solutions into the micro-channel structure to form at least three liquid film columns, where the first and second solutions include different solvent composition ratios and the liquid columns each, respectfully, include different solvent composition ratios. The method further includes detaching the platform the substrate, removing solvent from the liquid film columns to form thin film columns, and treating the thin film columns under different conditions along a length direction of the thin film columns. The solvent is removed from the thin film columns and the thin film columns are treated under different conditions along a length direction of the thin film columns.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: March 25, 2014
    Assignees: Samsung Electronics Co., Ltd., The United States of America as represented by the National Institutes of Health (NIH), The United States of America as represented by the Dept. of Health and Human Services (DHHS)
    Inventors: Jong Won Chung, Christopher J. Bettinger, Zhenan Bao, Do Hwan Kim, Bang Lin Lee, Jeong Il Park, Yong Wan Jin, Sang Yoon Lee
  • Microfluidic protein crystallography
    Patent number: 7927422
    Abstract: The use of microfluidic structures enables high throughput screening of protein crystallization. In one embodiment, an integrated combinatoric mixing chip allows for precise metering of reagents to rapidly create a large number of potential crystallization conditions, with possible crystal formations observed on chip. In an alternative embodiment, the microfluidic structures may be utilized to explore phase space conditions of a particular protein crystallizing agent combination, thereby identifying promising conditions and allowing for subsequent focused attempts to obtain crystal growth.
    Type: Grant
    Filed: December 2, 2008
    Date of Patent: April 19, 2011
    Assignees: National Institutes of Health (NIH), The United States of America as represented by the Dept. of Health and Human Services (DHHS), U.S. Government NIH Division of Extramural Inventions and Technology Resources (DEITR)
    Inventors: Carl L. Hansen, Morten Sommer, Stephen R. Quake