Abstract: The present invention provides a method of treating or preventing the inflammatory response of ulcerative colitis or Crohn's disease in a subject comprising administering to the subject an effective amount of a substance that inhibits the binding of IL-13 to IL-13 receptors on NKT cells or delivers an effector molecule to the NKT cells.
Type:
Grant
Filed:
April 14, 2006
Date of Patent:
July 7, 2015
Assignee:
The United States of America, as represented by the Secretary Department of Health by Human Servies
Inventors:
Warren Strober, Ivan Fuss, Peter Mannon, Jan Preiss, Raj Puri, Koji Kawakami, Stefan Fichtner-Feigl, Atsushi Kitani