Patents Assigned to The United States of America, as represented by the Secretary, Dept. of Health and Human Svcs.
  • USE OF ISOVALERYLSPIRAMYCINS AS ANTI-CANCER AGENTS TO INHIBIT METASTASIS
    Publication number: 20210283159
    Abstract: A pharmaceutical composition containing any one or more of 4?-O-isolvalerylspiramycin I, II and III counters tumorigenesis and reduces or prevents metastasis by inhibiting selenoprotein H to trigger genomic instability and cell-cycle arrest in cancer cells.
    Type: Application
    Filed: March 11, 2020
    Publication date: September 16, 2021
    Applicants: ASCLEA CORPORATION, THE UNITED STATES OF AMERICA, as represented by the Secretary, Dept, of Health and Human Svcs.
    Inventors: Enhong JIANG, Zhengping ZHUANG, Jing CUI
  • B CELL SURFACE REACTIVE ANTIBODIES
    Publication number: 20120121504
    Abstract: The invention relates to antibodies that are reactive to the cell surface of CD19+ B cells, including B-cell chronic lymphocytic leukemia (B-CLL) cells, and compositions and methods for using such antibodies, including in the diagnosis and treatment of disorders associated with CD19+ B cells, such as B-CLL.
    Type: Application
    Filed: May 12, 2010
    Publication date: May 17, 2012
    Applicant: The United States of America, as represented by the Secretary, Dept. of Health and Human Svcs.
    Inventors: Christoph Rader, Sivasubramanian Baskar, Michael R. Bishop, Ivan Samija, Jessica M. Suschak