Abstract: A method for computer-assisted planning of a transplant surgery is provided.

Abstract: A computer-assisted surgical system can include a donor sub-system and a recipient sub-system. The donor sub-system includes a first reference unit having a first trackable element, a fragment reference unit having a second trackable element, and a first detector configured to provide at least one of a first signal corresponding to a detected location of one or more of the first trackable element and the second trackable element. The recipient sub-system includes a second reference unit having a third trackable element, and a second detector configured to provide at least one of a second signal corresponding to a detected location of at least the third trackable element.

Abstract: A method for computer-assisted planning of a transplant surgery is provided.

Abstract: The present invention is directed to a method of continuously monitoring neuronal avalanches in a subject comprising (a) determining a deviation in avalanche exponent (?) or branching parameter (?) from a predetermined value at rest, wherein the pre-determined value of ? is a slope of a size distribution of the synchronized neuronal activity and the predetermined value is ?3/2 and the pre-determined value of ? is a ratio of successively propagated synchronized neuronal activity and the predetermined value is 1; and (b) repeating step (a) one or more times to continuously monitor neuronal avalanches in a subject. The invention also features methods of determining or monitoring the degree of sleep deprivation in a subject, methods of identifying subjects that are susceptible to a sleep disorder and methods of diagnosing a sleep disorder in a subject.

Abstract: A surgical guide assembly having an attachment device configured to be coupled to a bone. A cut location indicator is coupled to the attachment device. The cut location indicator identifies a location where the bone is to be cut. An arm is coupled to the attachment device, the cut location indicator, or both. A support structure is coupled to the arm. The support structure is configured to have a trackable feature coupled thereto.

Abstract: The present application describes a plurality of test simulation environment mimic complex listening environment of everyday life, comprising a speech component, and a noise component. The application also describes an auditory testing system and method for evaluating a listener's speech perception and method to test hearing prosthesis or hearing protection device's effect on a person's speech perception in a complex listening environment.

Abstract: Disclosed is a method of simulating mastication. The method includes obtaining computer-readable three-dimensional representations of a first skeletal fragment including a portion of at least one of a mandible and a maxilla and of a recipient skeletal fragment including a portion of at least one of a mandible and a maxilla. The method also includes obtaining placement data and obtaining muscle insertion data. The method also includes simulating a contraction of a muscle positioned according to the muscle insertion data in a representation of a surgical hybrid comprising at least a portion of the first skeletal fragment positioned according to the placement data relative to at least a portion of the recipient skeletal fragment. The method also includes outputting a representation of mastication represented by the simulating.

Abstract: The subject matter of the instant invention relates to a dental implant surgical apparatus and system comprising a customized dental ridge augmentation matrix and one or, optionally, a plurality of dental implant surgical drill guides, and methods of use thereof.

Abstract: An ophthalmic training simulator with simulated foreign objects and/or canthal tendons. A method of practicing foreign object removal from the eye and lateral canthotomy of the eye using said ophthalmic training simulator.

Abstract: A method of analyzing performance of frequency lowering hearing aids. The method includes generating a sequentially of noise signals and transmitting acoustical sounds from a sound output device in response to the sequence of noise signals. A sound input device records the acoustical sounds and saves as a first device data. The sound input device with a frequency lowering hearing aid records the acoustical sounds and save as a second device data. The second device data is compared to the first device data and, in response to the comparison, at least one function of the frequency lowering hearing aid is optionally adjusted.

Abstract: A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.

Abstract: A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.

Abstract: A system and method for optimally imaging the peripheral vasculature is disclosed which includes defining a given number of scan stations along a patient's peripheral vasculature and initially injecting a relatively small amount of contrast agent into the patient to pass a test bolus through the patient's peripheral vasculature, and thereafter tracking the test bolus through the patient and adjusting the patient on a moveable table within the MR imaging device from one scan station to a next station to determine a maximum travel time that the test bolus takes to travel through each of the given number of scan stations. Additional contrast agent is then injected into the patient to pass an exam bolus through the patient's peripheral vasculature, and using the test bolus travel time, MR data can be acquired from each scan station while it is known that the exam bolus is present in that station to optimize image resolution.

Abstract: An infrared (IR) radiation transducer integrates an IR detector array with a liquid crystal (LC) readout. The IR detector is preferably a pixelized bolometer array, but other detectors such as pyroelectric materials are possible. To modulate the LC in response to detected IR radiation, a modulating section is provided that includes a charge injection structure which injects electrical charge in response to the detected IR radiation, and a charge transfer structure that transfers the injected charge to the LC readout section. During its active phase the charge transfer layer is depleted of majority charge carriers, and the charge injection and transfer mechanism operates in a manner analogous to a bipolar transistor. A visible readout is obtained by directing readout light through the LC, where it is modulated in accordance with the detected IR image. The transducers are small and light weight enough to be incorporated into a pair of goggles, for which no separate cooling is required.