Abstract: Compositions and methods for detecting presence of an influenza virus in a sample, such as a biological sample obtained from a subject or an environmental sample, are provided. In some embodiments, the compositions and methods can be used to quickly identify particular subtypes of influenza virus (such as seasonal or variant influenza subtype H3, influenza subtype H5, Eurasian influenza subtype H7, North American influenza subtype H7, and/or influenza subtype H9) present in a sample. Probes and primers are provided herein that permit the rapid detection and/or discrimination of influenza virus subtype nucleic acids in a sample. Devices (such as arrays) and kits for detection and/or discrimination of influenza virus subtype nucleic acids are also provided.
Type:
Grant
Filed:
October 22, 2014
Date of Patent:
June 26, 2018
Assignee:
The United States of America, as represented by the Secretry, Department of Health and Human Services
Inventors:
Bo Shu, Stephen Lindstrom, Kai-Hui Wu, LaShondra Berman, Shannon L. Emery, Christine Warnes, Catharine McCord