Patents Assigned to The United States of America as represtented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention
  • Rabies virus vector systems and compositions and methods thereof
    Patent number: 8865461
    Abstract: Rabies Virus compositions and methods are provided. The full-length sequence of Rabies Virus strain Evelyn-Rokitnicki-Abelseth (ERA) is disclosed. A reverse genetics system for producing recombinant ERA virus and derivatives thereof is provided, along with compositions including ERA and/or ERA derivative strain viruses, nucleic acids and/or proteins. In some instances, the compositions are immunogenic compositions useful for the pre- or post-exposure treatment of Rabies Virus.
    Type: Grant
    Filed: November 30, 2010
    Date of Patent: October 21, 2014
    Assignee: The United States of America as represtented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention
    Inventors: Charles E. Rupprecht, Xianfu Wu