Patents Assigned to The United States of America, as repsented By the Secretary, Department of Health and Human Services
  • NEUTRALIZING ANTIBODIES TO GP120 AND THEIR USE
    Publication number: 20180298083
    Abstract: Antibodies and antigen binding fragments that specifically bind to gp120 and neutralize HIV-1 are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed.
    Type: Application
    Filed: March 18, 2016
    Publication date: October 18, 2018
    Applicant: The United States of America, as repsented By the Secretary, Department of Health and Human Services
    Inventors: Mark Connors, Jinghe Huang, Byong Ha Kang, John Mascola, Elise Ishida, Tongqing Zhou, Peter Kwong, Anqi Zheng