Abstract: The present disclosure relates to T24 nucleic acid sequences, amino acid sequences, and antibodies. Methods for detecting and diagnosing Taenia solium infection in a subject using the T24 sequences and specific binding agents are also disclosed. The T24 sequences disclosed herein can be formulated into a pharmaceutical composition for administration to a subject. For example, the disclosed T24 polypeptides can also be administered to a subject to stimulate an immune response in the subject, thereby protecting the subject against T. solium infection.
Type:
Grant
Filed:
April 29, 2009
Date of Patent:
July 5, 2011
Assignee:
The United States of America as respresented by the Department of Health and Human Services
Inventors:
Kathy Hancock, Fatima Williams Whitfield, Melinda L. Yushak, Sowmya Pattabhi, Victor C.W. Tsang
Abstract: A method of simultaneously measuring thermal conductivity and heat capacity of a fluid, using a heat conduction calorimeter having a reference fluid in a first cell and a sample fluid in a second cell includes the steps of calibrating the calorimeter using a standard fluid having known thermal conductivity and heat capacity over a range of temperatures and the reference fluid to determine a set of sensitivity parameters, {a.sub.n.sup.ij }, of the calorimeter, wherein the a.sub.n.sup.ij are functions of the calorimeter, temperature and the reference fluid; applying a square wave heat pulse to the calorimeter containing said sample fluid and said reference fluid; measuring the thermal response curve to the square wave heat pulse, wherein the thermal response curve is a function of time, temperature of the measurement, thermal properties of the sample fluid, and thermal properties of the reference fluid; reducing the response curve to a set of discrete characteristic parameters, {p.sub.
Type:
Grant
Filed:
December 19, 1997
Date of Patent:
November 23, 1999
Assignee:
The United States of America as respresented by the Department of Health and Human Services
Inventors:
Norman Gershfeld, Courtney Mudd, Albert Jin, Kazuhiro Fukada