Patents Assigned to THE UNITED STATES OF AMERICA DEPT. OF VETERANS AFFAIRS
  • Method for modulating or controlling sodium channel current by reactive oxygen species (ROS) originating from mitochondria
    Patent number: 9114151
    Abstract: Method for modulating or controlling sodium channel current of a cell includes inducing mitochondrial reactive oxygen species (ROS) production in the cell.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: August 25, 2015
    Assignees: THE UNITED STATES OF AMERICA DEPT. OF VETERANS AFFAIRS, THE BOARD OF TRUSTEES OF THE UNIV. OF ILLINOIS
    Inventor: Samuel C. Dudley, Jr.
  • Antagonistic analogs of GH RH (2003)
    Patent number: 7452865
    Abstract: There is provided a novel series of synthetic antagonistic analogs of hGH-RH(1-29)NH2. These analogs inhibit the activity of endogenous hGH-RH on the pituitary GH-RH receptors, and therefore prevent the release of growth hormone. The analogs also inhibit the proliferation of human cancers through a direct effect on the cancer cells. The higher inhibitory potencies of the new analogs, as compared to previously described ones, results from replacement of various amino acids.
    Type: Grant
    Filed: July 26, 2004
    Date of Patent: November 18, 2008
    Assignees: The Administrare's of the Tulane Educational Fund, United States of America by Dept of Veterans Affairs
    Inventors: Andrew V. Schally, Jozsef Varga, Marta Zarandi, Ren Zhi Cai