Abstract: The adaptive body bending estimator comprises a band pass filter which receives an accelerometer signal from a missile's accelerometer. The band pass filter, which has a bandpass of 25-70 hertz, rejects frequencies which are not of interest. The band-passed signal is then supplied to a notch filter bank comprising six notch filters within a frequency range of between 42 hertz and 55 hertz. The six notch filters are centered at different frequencies, the frequencies being 42 Hz, 44.32 Hz, 46.78 Hz, 49.37 Hz, 52.11 Hz and 55.00 Hz. The notch filters reject signals at these frequencies. The signals from the filter bank are supplied to an absolute value generator which generates an absolute value for each signal. The absolute value of each signal is passed through a low pass filter bank. The low pass filter bank processes these absolute value signals providing a time weighted average for each signal. The low pass filter bank provides its output signals to a find frequency module.

Abstract: An energy-absorbing countermass assembly for a weapon has a crushable section, a piston at the forward end of the crushable section, and at the rearward end of the crushable section. The countermass can be a rupturable enclosure filled with a dispersible material.

Abstract: The invention provides methods for inhibiting the growth of a cell bearing a LewisY antigen. The methods involve contacting the cell with a composition comprising an Fv region of a light chain of a monoclonal antibody selected from B1, B3, and B5, and the Fv region of a humanized heavy chain of a monoclonal antibody independently selected from B1, B3, and B5, provided that if the heavy and the light chains are from the same antibody, the residue at position 95 of the heavy chain is a serine, and, if the antibody chain is from B3, the residue at position 4 of the light chain can be a leucine and the residue at position 82b of the heavy chain can be an arginine. The Fv regions are joined to an effector molecule selected from a chemotherapeutic agent, a toxin, a radioisotope, and a liposome loaded with a chemotherapeutic agent. In preferred embodiments, the heavy chain and the light chain are recombinantly fused, and the Fv regions are recombinantly fused to a toxin.

Abstract: A catalytic heater supplies heated water that circulates to heat a diver's suit. An insulating housing closed at opposite ends by cap members defines a chamber containing a catalyst inside of a multi-tube heat exchanger. Fittings in the cap members pass water through the multi-tube heat exchanger to and from the suit, and a gas circuit flows mixed hydrogen and oxygen to the catalyst that reacts with the mixed hydrogen and oxygen to produce heat that heats the water in the multi-tube heat exchanger for the diving suit. Optionally, hydrogen may be mixed with oxygen from a breathing gas mixture so that after heating the water, the gases remaining may be breathed by the diver. The catalytic heater provides a safe, reliable source of warm water for active thermal protection of divers over a wide range of diving applications.

Abstract: A sealed slotted cylinder includes an active transducer assembly, end caps at each end of the assembly, and a boot fused to the end caps and sealing the assembly. The sealed slotted cylinder is made using a dummy insert and a spacer within the dummy insert for spacing the end caps. A boot material made from an uncured rubber is wrapped around the dummy insert and the end caps. This assembly is placed in a mold that fuses the boot material to the end caps by vulcanizing the uncured rubber material. The mold and dummy insert preferably form longitudinal and circumferential boot roll seals on the boot material. A section of the boot is then removed forming an open region, allowing the dummy insert and spacer to be removed. The active transducer assembly can then be inserted through the open region such that the longitudinal boot roll seal engages and seals the slot in the active transducer assembly and the circumferential boot roll seals engage the end of the active transducer assembly.

Abstract: A fiber optic sensor array has multiple segments, each capable of detecting a physical condition such as an acoustic wave. The segments are separated by weak reflectors such as fiber optic Bragg gratings. Light from a light source is input into the input end of the array. Light reflected by each of the reflectors has a phase shift representing the effects of the physical condition on all of the segments from the input end to that reflector. To address a specific reflector, the return light is demultiplexed. This demultiplexing is done by modulating the light input into the input end of the array with a pseudo-random bit sequence and correlating the output with a time-shifted version of the pseudo-random bit sequence to isolate the part of the output caused by that reflector. To address a specific segment, the phase shifts from two adjacent reflectors are determined. The return light can be strengthened by mixing it with a portion of the light picked off from the light source.

Abstract: A controlled stochastic resonance circuit applies stochastic resonance to bias a nonlinear device with a control signal having a selected amplitude, frequency, and phase to enhance or suppress the response of the device to a periodic signal embedded in noise.

Abstract: Compounds, compositions and methods are provided for treating malaria parasites in vitro and in vivo by administering indolo[2,1-b]quinazoline-6,12-dione compounds of Formula I.

Abstract: A modular launching system is disclosed that reduces the reinforcement needs of mating a launching system to a ship, while at the same time reduces stress concentration and foundation movements created by the modular launching system launching launchable devices.

Abstract: A dual-energy x-ray system is provided which is useful in densitometry and other applications. A dual energy x-ray source, formed field emission x-ray tube driven by a Marx generator, produces a single x-ray pulse of a very short duration (e.g., 10 to 200 nanoseconds). The pulse provides x-ray energy of a first, high value early in the pulse and x-ray energy of a second, lower value later in the pulse so as to provide a dual energy level x-ray distribution comprising hard and soft x-rays. A detector system having dual x-ray energy discrimination properties, formed by soft and hard x-ray detectors and an inter-detector, receives the x-ray pulse and discriminates between the dual x-ray energy levels of the pulse.

Abstract: A safety switch is provided to detect when a tube launched which exits the tube. The switch is located within the vehicle having a switch plunger extending to the periphery of the vehicle. The plunger is biased to provide outward pressure against a lever on the exterior of the vehicle. The lever rides within the bore of the launch tube such that, when the vehicle is within the launch tube, the lever contacts the interior bore of the tube. The lever contacting the tube bore prevents the plunger from extending to activate the switch. When the vehicle exits the tube, the lever is free to rotate away from the vehicle allowing the plunger to extend and activate the switch which may be a single or multi-pole switch.

Abstract: This invention involves a hard target penetrating warhead designed to produce a variable explosive discharge. A standard warhead casing is divided into several compartments with each compartment separated by a shock-absorbing shield. Explosive fill in contained within each compartment. The shock-absorbing shield inhibits the dynamic shock produced by detonating a compartment, thus preventing sympathetic detonation of adjoining compartments. As a result, the size of an explosive blast is controlled by detonating the explosive fill, in a set number of compartments. Each compartment also contains an igniter element, which initiates a slow burn of undetonated explosive fill.

Abstract: A dielectric thin-film material for microwave applications, including use as a capacitor, the thin-film comprising a composition of barium strontium calcium and titanium of perovskite type (BaxSryCa1−x−y)TiO3. Also provided is a method for making a dielectric thin film of that formula over a wide compositional range through a single deposition process.

Abstract: A near field optical microscope according to the present invention has (1) a single mode infrared optical fiber made from chalcogenide glass, chalcohalide glass, or a combination thereof, having a probe end adapted as a probe for near field optical microscopy, and further adapted for positioning within a near optical field of a sample; (2) a source of infrared light; for illuminating the sample; (3) a detector of infrared light; for detecting infrared light reflected from, emitted by, or transmitted through the sample, where at least one of the source of infrared light and the detector of infrared light are optically coupled to a distal end of the single mode infrared optical fiber.

Abstract: Substantially pure recombinant TSH has been prepared from a clone comprising complete nucleotide sequence for the expression of the TSH. Diagnostic and therapeutic applications of the synthetic TSH are described.

Abstract: A pressure clip for contacting a heat sink device to a heat sink by means of a pressure bond having thermal resistance of less than about 5 K/kW/cm2. The pressure clip includes a mounting block, a clamp block; a spacer disposed between the mounting block and the clamp block forming a channel therebetween, support shoulders in the channel for supporting a heat sink, means for securing the clamp block and the spacer to the mounting block, pressure arm disposed above the mounting block, flexible joint for flexibly attaching the pressure arm to the mounting block, pressure screw disposed between the pressure arm and the mounting block for applying pressure to the pressure arm, and a plunger projecting into the channel between the mounting block and the clamp block for transmitting pressure from the pressure arm.

Abstract: A compact wideband leaky-wave excitation microstrip antenna is provided by a group of microstrip patches disposed on a top region of a dielectric substrate stacked on a conductive ground plane. The top region of the dielectric substrate and the dielectric substrate can be composed of either the same or different dielectric materials. A means for feeding an RF signal, which can be a center feed pin, that normally touches the top conducting patch is electrically isolated from the radiating patches. This arrangement confines the feed current within the probe pin to give an increased input resistance. The compact wideband leaky-wave excitation microstrip antenna permits significant reductions in antenna size, resulting in microstrip antennas with a smaller surface area.

Abstract: A barrier layer for a silicon containing substrate which inhibits the formation of gaseous species of silicon when exposed to a high temperature aqueous environment comprises a calcium alumino silicate.

Abstract: The respiratory syncytial virus (RSV) is a major cause of lower respiratory tract disease in infants and children throughout the world. RSV is a major cause of pneumonia and bronchiolitis in infants under one year of age, and is a major cause of fatal respiratory tract disease in these infants. The treatment and prevention of RSV infection has been problematic. However, the present invention addresses some of these concerns by providing attenuated RSV strains that are suitable for inclusion in immunizing compositions. Specifically, the present invention is directed toward the introduction of growth restriction mutations into incompletely attenuated host range-restricted cold-passaged respiratory syncytial virus (cpRSV) strains by further passage of the strains at increasingly reduced temperatures to produce derivative strains which are more satisfactorily attenuated.

Abstract: Methods are presented to produce duplex (DP) microstructures, nearly lamellar (NL) microstructures, and fully TMT lamellar (TMTL) microstructures in gamma titanium aluminide alloy articles. The key step for obtaining a specific type of microstructure is the post-hot work annealing treatment at a temperature in a specific range for the desired microstructure. The annealing temperatures range from Te+100° C. to T&agr;−25° C. for duplex (DP) microstructures, from T&agr;−25° C. to T&agr;−5° C. for nearly lamellar (NL) microstructures, and from T&agr; to T&agr;+60° C. for fully TMT lamellar (TMTL) microstructures, where Te is the titanium-aluminum eutectoid temperature of the alloy and T&agr; is the alpha transus temperature of the alloy. The times required for producing specific microstructures range from 2 min to 15 hours depending on microstructural type, alloy composition, annealing temperature selected, material section size, and desired grain-size.