Abstract: A laser interferometer, such as a dual path Michelson interferometer, is used to generate fringe patterns resulting from one of a plurality of optical paths passing through a sample gas. An artificial neural network, such as, for example, a KASER neural network, is used to recognize patterns in the fringe interference patterns corresponding to known target gases.

Abstract: This invention pertains to a product and a method for preparing same. The product is an electrically conducting metallized fibers and a non-conducting composite containing the metallized fibers. In a preferred embodiment, the product is a composite of metallized cellulose fibers disposed in an electrically non-conducting matrix. The method includes the steps of hydrating cellulose fibers to prevent absorption of chemical reagents; activating the cellulose surface of the fibers for metal deposition; removing from the fibers excess activator and reagents used in the activation; drying the fibers to a free-flowing condition whereby the fibers acquire the color of the activator by virtue of its deposition on the fibers; metallizing the fibers to deposit thereon a metal capable of absorbing electromagnetic radiation; drying the metallized fibers whereby they are free-flowing; and forming a composite composed of an electrically non-conductive matrix having dispersed therein the matallized fibers.

Abstract: A laser Doppler vibrometer for vibration measurement that employs active feedback to cancel the effect of large vibration excursions at low frequencies, obviating the need to unwrap phase data. The Doppler shift of a reflective vibrating test object is sensed interferometrically and compensated by means of a voltage-controlled oscillator driving an acousto-optic modulator. For frequencies within the servo bandwidth, the feedback signal provides a direct measurement of vibration velocity. For frequencies outside the servo bandwidth, feedback biases the interferometer at a point of maximal sensitivity, thus enabling phase-sensitive measurement of the high-frequency excursions. Using two measurements, one with a low bandwidth and one with a high bandwidth, more than five decades of frequency may be spanned.

Abstract: The present invention relates to a method of expressing an immunotoxin in Pichia pastoris strain mutated to toxin resistance comprising a) growing the Pichia pastoris in a growth medium comprising an enzymatic digest of protein and yeast extract and maintaining a dissolved oxygen concentration at 40% and above; and b) performing methanol induction with a limited methanol feed of 0.5-0.75 ml/min/IO L of initial volume during induction along with a continuous infusion of yeast extract at a temperature below 17.5° C., antifoaming agent supplied up to 0.07%, agitation reduced to 400 RPM, and the induction phase extended out to 163 h.

Abstract: A method for in vivo, ex vivo and in vitro regeneration of cartilage, collagen and bone remodeling by intermittently applied hydrostatic pressure consisting of repeated periods of applied hydrostatic pressure followed and interrupted by periods of recovery. The intermittent hydrostatic pressure is applied at physiological levels 5-10 MPA for an interval of 4 hours followed by a recovery period up to about 20 hours. The interval loading results in the selective inhibition of matrix degrading enzymes, pro-inflammatory cytokines and chemokines that attract inflammatory cells into the joint cavity and in selective decrease of gene expression of growth factors that are inhibitory to type II collagen expression.

Abstract: The present invention provides methods an compositions for diagnosis and treatment of carcinomas with aberrant expression patterns of POT 1. The invention also provides methods of identifying compounds that may modulate the cellular expression of POT 1. The invention further provides methods for treating subjects suffering from or at risk of developing a colorectal carcinoma.

Abstract: An assembly of connected circuit boards includes at least one each of a matrix board, an input board and an output board. There are two types of input board, one for hydrophone cable input and one for single-ended (SE) cable input. The matrix board provides for switching any pair of input differential signals to any channel on the output board.

Abstract: It is disclosed herein that agents that affect the activity and/or expression of CXCL16 can be used to alter the uptake of D-type CpG oligodeoxynucleotides (D ODNs). Methods of inducing an immune response are disclosed that include administering agents that increase the activity and/or expression of CXCL16 and a D ODN. Methods of decreasing an immune response to a CpG ODN are also disclosed. These methods include administering an agent that decreases the activity and/or expression of CXCL16. Compositions including one or more D-type ODNs and an agent that modulates that activity and/or expression of CXCL16 are provided.

Abstract: A process is provided for disposing a sensor in an environment for optimally obtaining characteristic measurements. The process includes modeling covariant sets of environment elements that correspond to conditions of the environment and of sensor elements that correspond to characteristic functionalities of the sensor. The process further includes covariantly coupling the environmental elements with the sensor elements to produce a third set of configuration elements; and combining the configuration elements to obtain a fitness function parameter. The process may additionally include adjusting the environment elements and the sensor elements; repeating operations for covariantly coupling and combining until obtaining the fitness function parameter over a defined region of the environment within a set of fitness function parameters.

Abstract: Electrochemical biosensors, methods of making biosensors and methods of detecting a target analyte in a sample to be analyzed are provided. A preferred embodiment device comprises a non-conductive polymer deposited on the electrode to form a matrix material having a plurality of pores; a capture biomolecule immobilized on the electrode such that the binding of the target analyte to the capture biomolecule effectively blocks a sufficient number of pores in the matrix material to produce a measurable decrease in the rate of a redox reaction occurring at the electrode; a current source for driving a redox reaction at the electrode; a redox species in contact with the electrode; and a detector element operatively connected to the electrode to detect the measureable decrease of a change in the rate of a redox reaction occurring due to the blockage of pores in the matrix material by the target analyte.

Abstract: A device and method of geolocating a transmitter. First and second receivers, in motion, receive a signal from the transmitter. Digitizers in the receivers digitize the signal. Converters in the receivers for converting the digitized signals to complex-valued signals. Transmitters on the receivers transmit their digitized signals, locations, and velocities at the time the signal was received to a processor. A central processing unit on the processor determines a difference in radial velocities of the receivers relative to the transmitter. The difference in radial velocities and delay time between the signals received at the receivers are used to geolocate the transmitter.

Abstract: A thermally stable chalcogenide glass, a process for making the same, and an optical fiber drawn therefrom are provided. A chalcogenide glass having the composition Ge(5?y)As(32?x)Se(59+x)Te(4+y) (0?y?1 and 0?x?2) is substantially free from crystallization when it is heated past the glass transition temperature Tg or drawn into optical fibers. A process for making the thermally stable chalcogenide glass includes purifying the components to remove oxides and scattering centers, batching the components in a preprocessed distillation ampoule, gettering oxygen impurities from the mixture, and heating the components to form a glass melt. An optical fiber formed from the chalcogenide glass is substantially free from crystallization and exhibits low signal loss in the near-infrared region, particularly at wavelengths of about 1.55 ?m.

Abstract: A method of improving efficiency of manufacturing a vacuum electronic device, includes placing sensors on the device's interior during its construction and obtaining a first measured characteristic value; comparing the first measured characteristic value with a desired characteristic value; determining whether the first measured characteristic value is within a predetermined percentage of the desired characteristic value; adjusting a component of the device and measuring the characteristic of the device to obtain a second measured characteristic, comparing the second measured characteristic value with a desired characteristic value, determining whether the second measured characteristic value is within a predetermined percentage of the desired characteristic value; and repeating the previous step until the second measured characteristic value is within the predetermined percentage of the desired characteristic value.

Abstract: The invention generally relates to the field of computer software particularly to an improved method of providing aircrew decision aids for use in determining the optimum placement of an Electronic Attack (EA) aircraft. The core of the invention is a software program that will dynamically provide the EA flight crew situational awareness regarding a threat emitter's coverage relative to the position of the EA aircraft and to the position of any number of protected entities (PE). The software program generates information to provide visual cues representing a Jam Acceptability Region (JAR) contour, a Jam Assessment Strobe (JAS) and text for display on a number of flexibly configurable display formats posted on display units. The JAR and JAS graphics and text will aid the EA aircrew in rapidly assessing the effectiveness of a given jamming approach.

Abstract: A method of assessing security of an information access system by selecting at least one verification mechanism, estimating an error tradeoff plot showing false acceptance rate versus false rejection rate for each verification mechanism, selecting a corresponding false acceptance rate and false rejection rate pair from each error plot, combining the false acceptance rates to determine intrusion protection, combining the false rejection rates to determine denial protection, and combining intrusion protection and denial protection as the assessment of the information access system.

Abstract: The inventive data conversion device is typically embodied as a modular unit including a PCBA and a frame that houses it. The PCBA includes a PCB and electronic components mounted thereon including a computer and one or more conventional conversion devices, viz., at least one conventional synchro-to-digital converter and/or at least one conventional digital-to-synchro converter. According to typical inventive synchro-to-digital conversion, analog synchro data (received from a synchro) is converted by the synchro-to-digital converter(s) to lower-level-format parallel-binary-angle digital synchro data, which in turn is converted by the computer to higher-level-format digital synchro data.

Abstract: A method of making metal nanoparticles and carbon nanotubes is disclosed. A mixture of a transition metal compound and an aromatic polymer, a precursor of an aromatic polymer, or an aromatic monomer is heated to form a metal nanoparticle composition, optionally containing carbon nanotubes.

Abstract: A composition comprising: a metal oxide of a first metal ions and second metal ions; an electrically conductive material; and a binder material. The second metal ions have a higher oxidation state than the first metal ions. The presence of the second metal ion increases the number of metal cation vacancies. A method of: dissolving salts of a first metal ion and a second metal ion in water to form a solution; heating the solution to a temperature of about 80-90° C.; and adding a base to the solution to precipitate nanoparticles of a metal oxide of the first metal ion and the second metal ion.

Abstract: A method and system for determining damage prediction of a component. The component may be critical component used in an aircraft or other vehicle experiencing cyclic loading. The method and system determines the ?K, Kmax and Kinternal values for the component and utilizes these values in order to predict damage and/or failure of the component.

Abstract: The flow-through area of a pressure regulator positioned in a branch of a simulated fluid flow network is generated. A target pressure is defined downstream of the pressure regulator. A projected flow-through area is generated as a non-linear function of (i) target pressure, (ii) flow-through area of the pressure regulator for a current time step and a previous time step, and (iii) pressure at the downstream location for the current time step and previous time step. A simulated flow-through area for the next time step is generated as a sum of (i) flow-through area for the current time step, and (ii) a difference between the projected flow-through area and the flow-through area for the current time step multiplied by a user-defined rate control parameter. These steps are repeated for a sequence of time steps until the pressure at the downstream location is approximately equal to the target pressure.