Abstract: The present invention relates to a method of isolating fragments of nucleic acid according to the density of CpG dinucleotides and subsequent procedures for producing a library and/or an array or microarray of these fragments, as well as uses thereof.

Abstract: A capacitive switch for microelectromechanical systems (MEMS) comprises a topmost metal plate which extends across a bridge structure formed by a polymer layer. The polymer layer comprises poly-monochoro-para-xylene (parylene-C). The space below the polymer layer contains the second plate on a substrate. Using parylene as the primary bridge material makes the bridge of the MEMS device very flexible and requires a relatively low actuation voltage to pull the bridge down and lower power is required to control the MEMS device.

Abstract: A spatial modulation method and transmitting and receiving apparatuses using the spatial modulation method in a MIMO system are provided. The spatial modulation method uses an index of an activated antenna and a signal modulation constellation as an information source. The spatial modulation method is applied to the transmitting apparatus. The receiving apparatus uses a spatial modulation detection method in which a channel path gain is repeatedly multiplied to detect the spatially modulated signal efficiently.

Abstract: Provided is a multiple-input multiple-output (MIMO) data transmission method. A transmitter generates a transmission symbol by adding a parity symbol to a predetermined number of data symbols, generates a preprocessed symbol by multiplying the predetermined number of transmission symbols by a preprocessing matrix in units of blocks, selects a transmission antenna associated with a non-zero transmission symbol among preprocessed transmission symbols constituting the preprocessed symbol, and transmits the preprocessed symbol via the selected transmission antenna. A receiver receives a signal transmitted from the transmitter, estimates a preprocessed symbol and a transmission antenna index from the received signal, and restores the transmission symbols using the estimated preprocessed symbol and transmission antenna index.

Abstract: The invention relates to a generator, to a magnetic flux conducting unit for a generator, and to a power generation machine comprising such a generator. In an embodiment of the invention, a generator is disclosed which comprises at least one coil assembly and at least one magnetic flux conducting unit. The magnetic flux conducting unit comprises at least one magnet, a pair of opposed magnetic flux conducting elements defining a space therebetween for receiving the coil assembly, and at least one connection portion extending between the opposed magnetic flux conducting elements. The at least is arranged relative to the opposed magnetic flux conducting elements such that the magnetic attraction forces between the elements are redacted through and balances with the connection portion.

Abstract: The present invention relates to the field of gels. The invention also relates to an improved method for manufacturing gels. In particular the invention relates to a new class of material, fluid-bicontinuous particle-stabilized gels, and a method of making the same. The fluid-bicontinuous particle-stabilized gels comprise at least a first fluid, a second fluid, and a continuous layer of particles positioned at a continuous interface between the first fluid and the second fluid.

Abstract: The present invention relates to a novel antibody which selectively binds to the disease associated form of prion protein (PrPSc) under native conditions and the use thereof in methods of prion disease detection, therapy and disease research in general.

Abstract: A semiconductor device includes a semiconductor substrate, a photon avalanche detector in the semiconductor substrate. The photon avalanche detector includes an anode of a first conductivity type and a cathode of a second conductivity type. A guard ring is in the semiconductor substrate and at least partially surrounds the photon avalanche detector. A passivation layer of the first conductivity type is in contact with the guard ring to reduce an electric field at an edge of the photon avalanche detector.

Abstract: The present invention provides methods for identifying whether or not a patient has, or is at risk of developing drug induced organ damage and methods of treating patients having drug induced organ damage. In particular, the invention relates to a method for identifying whether or not a patent has, or is at risk of developing paracetamol induced liver damage.

Abstract: Disclosed is a polymer having an affinity for corneal cells such that it can be used as a substrate for the growth of corneal cells, and so is suitable for use in a corneal bandage, especially in the form of a contact lens in which at least the cornea contacting surface is composed of the polymer. The substrate with an affinity for corneal cells is a copolymer comprising units -(A)- and -(B)- in which the units A are derived from aminoalkyl (alkyl)acrylates and the units B are derived from aryloxy, alkoxy or hydroxyalkyl (alkyl)acrylates, and (alkyl)acrylic acids.

Abstract: A micro electromechanical (MEMS) antenna (36) is positioned on one side of a substrate and is connected to a MEMS switch comprising a capacitor bridge (46) and to a transmission line (42) by means of a thru hole or via (48) which forms an electrically conducting path through the substrate. This arrangement provides a common ground plane for the antenna and switch and shields the switch from the electromagnetic radiation received or transmitted from the antenna. The switch may comprise a topmost metal layer which extends across a bridge structure formed by a polymer layer (19). The polymer layer comprises poly-monochloro-para-xylene (parylene-C). Homogeneous or heterogeneous antenna array structures are implemented. The antenna arrays may include one or more different type of antennas with for example different shapes, rotations and reflections.

Abstract: The present invention relates to the discovery that renewable stem cell lines can be derived from tumor cells and can be cultured in vitro. Accordingly, the invention provides neural tumor stem cell lines and cells from such cell lines. Because the cell lines retain characteristics of the tumors from which they are derived, the cells can be used in screening methods for identification of potential therapeutic agents and can be used to identify genetic markers which may be predictive for development of such tumors. Finally, such cells can be used to determine an appropriate therapeutic regimen for a patient suffering from a brain tumor. Cells from a patient's brain tumor can be cultured as described herein to create a cell line, and the relative effectiveness of a therapeutic agent against the cells can be tested to determine which agent or combination of agents is most effective in treating the patient's tumor.

Abstract: A cellular communication system and method supporting both a time division duplexing (TDD) scheme and a frequency division duplexing (FDD) scheme. The apparatus includes a plurality of mobile stations, at least three first fixed stations communicate with the mobile station based on the FDD scheme, the first fixed station defining respective macro cells that are contiguous and form a virtual cell, and a cluster including at least one second fixed station communicating with the mobile stations based on the TDD scheme, the second fixed station defining a micro cell in the virtual cell.

Abstract: A method for generating a culture that is purified or enriched in respect of cells of a selected lineage is described in which a selectable marker, which is differentially expressed in cells of the selected lineage compared with its expression in other cells, is introduced into a multipotential cell and the multipotential cell is cultured to induce differentiation of the multipotential cell into a cell of the selected lineage or into a mixture of cells including cells of the selected lineage, or is cultured to induce preferential survival of cells of the selected lineage. Those cells that express the selectable marker are then selected for. Progenitors of selected lineage are also described as is the use of the method in assay techniques.

Abstract: A system for testing visual fields comprising a display for presenting a visual stimulus and an eye tracker for tracking movement of at least one of a patient's eyes to determine its position in three dimensions without requiring the patient to wear any tracking equipment. A computer controls the position of the stimulus on the display and causes it to move by an amount that is a function of the tracked three-dimensional position of the patient's eye and a visual field position that is to be tested. Changes to the position of the stimulus and any corresponding tracked eye movement are used to assess the patient's visual field.

Abstract: A semiconductor device includes a semiconductor substrate, a photon avalanche detector in the semiconductor substrate. The photon avalanche detector includes an anode of a first conductivity type and a cathode of a second conductivity type. A guard ring is in the semiconductor substrate and at least partially surrounds the photon avalanche detector. A passivation layer of the first conductivity type is in contact with the guard ring to reduce an electric field at an edge of the photon avalanche detector.

Abstract: The present invention relates to agents which are capable of inducing analgesia in chronic neuropathic pain, associated methods and uses thereof. In particular, the present invention provides compounds capable of activating the TRPM8 receptor for the treatment of chronic neuropathic pain.

Abstract: A reconfigurable processor architecture, compiler and method of program instruction execution provides reduced cost, short design time, low power consumption and high performance. The processor executes program instructions having datapaths of both dependent and independent program instructions. Simultaneous multithreading is also Interconnects Network supported. The processor has a reconfigurable core (1) with an interconnection network (4) and a heterogeneous array of instruction cells (2) each connected to the interconnection network (4). A decoding module (11) receives configuration instruction (10), each instruction encoding the mapping of one of the datapaths to a circuit of the instruction cells (2). The decoding module (11) decodes each configuration instruction (10) and configures the interconnection network (4) and instruction cells in order to map the datapath to the circuit of the instruction cells and execute the program instructions.

Abstract: In a mobile ad hoc network, a method of routing data and a mobile unit for use according to the method are arranged to find the relay capacity of a node and the lifetime of the node, and thereby determine whether the node can relay the data. The method and unit can find the relay efficiency of nodes and this information is used to route data traffic efficiently through a number of nodes along a route.