Abstract: We describe modified bacterial cells that are defective in gene expression and their use in the treatment of bacterial infections of animals and plants and the inhibition of bacterial biofilm formation.
Type:
Application
Filed:
September 22, 2009
Publication date:
December 22, 2011
Applicants:
The University of Nottingham, Texas Tech University System Office of Technology Transfer and Intellectual Property, University Court of the University of Edingburgh
Inventors:
Stephen Diggle, Shanika Crusz, Stuart West, Ashleigh Griffin, Kendra Rumbaugh
Abstract: Pluripotent cells are maintained in a self-renewing state in serum-free culture medium comprising a MEK inhibitor, a GSK3 inhibitor and, optionally, an antagonist of an FGF receptor. Pluripotent cells are also maintained in a self-renewing state in serum-free culture medium comprising a MEK inhibitor and an antagonist of an FGF receptor.
Type:
Application
Filed:
October 20, 2009
Publication date:
February 18, 2010
Applicant:
The University Court of the University of Edingburgh