Patents Assigned to The University Court of the University of Glasgow
  • Patent number: 11311686
    Abstract: A device is disclosed for the preparation of nebulised droplets, for inhalation. The device has: a surface acoustic wave (SAW) transmission surface; a SAW transducer adapted to generate and propagate SAWs along the SAW transmission surface; and an array of cavities opening at the SAW transmission surface for containing a liquid. In operation, SAWs propagating along the SAW transmission surface interact with the liquid in the cavities to produce nebulised droplets of the liquid. Operation of the device results in a nebulised plume of droplets of average diameter in the range 1-5 ?m.
    Type: Grant
    Filed: November 11, 2015
    Date of Patent: April 26, 2022
    Assignee: The University Court of the University of Glasgow
    Inventors: Julien Reboud, Robert Wilson, Jonathan Cooper
  • Patent number: 11056531
    Abstract: A method of fabricating a field-effect transistor in which a native oxide layer is removed prior to etching a gate recess. The cleaning step ensures that the etch of the gate recess starts at the same time across an entire sample, such that a uniform gate recess depth and profile can be achieved across an array of field-effect transistors. This results in a highly uniform switch-off voltage for the field-effect transistors in the array.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: July 6, 2021
    Assignee: The University Court of the University of Glasgow
    Inventors: David Robert Sime Cumming, Chengzhi Xie, Vincenzo Pusino
  • Patent number: 11050219
    Abstract: A laser device has a photonic crystal surface emitting laser (PCSEL) element. At a first lateral side of the PCSEL element, a reflector is arranged to reflect back into the PCSEL element at least a portion of light travelling out of the PCSEL element through the first lateral side of the PCSEL element. Between the first lateral side of the PCSEL element and the reflector there is interposed an electrically controllable light-transmission region configured to control the transmission of light from the PCSEL element to the reflector, based on an electrical input. Also disclosed is a method of operation of a corresponding laser device.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: June 29, 2021
    Assignee: The University Court of the University of Glasgow
    Inventors: Richard Hogg, David Childs, Richard Taylor
  • Publication number: 20210154858
    Abstract: This invention relates to a device for sensing interaction with its surrounding environment, the device including: a plurality of sensing points (11); a plurality of detectors (12), each associated with one of said sensing points (11) and located remotely therefrom; a plurality of channels (14) which connect said sensing points (11) to said detectors (12) and provide a communication pathway therebetween; and communication media filling the channels, wherein each detector (12) is in communication with the associated sensing point or points (11) through one of said channels (14) and the medium in said channel (14) is arranged to transmit, transfer or transduce an interaction of the sensing point (11) with its surrounding environment to the detector (12) through the channel (14). The invention also relates to prosthetics which incorporate such devices.
    Type: Application
    Filed: May 14, 2018
    Publication date: May 27, 2021
    Applicant: THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW
    Inventors: Ravinder DAHIYA, Dhayalan SAKTHIVEL, William Navaraj TAUBE
  • Patent number: 10802042
    Abstract: An acceleration measuring device is disclosed, for use as a gravimeter or gradiometer for example. The device has a support and a proof mass, connected to each other by at flexures allowing displacement of the proof mass relative to the support. The support defines a space for displacement of the proof mass. The device is configured so that the modulus of the gradient of the force-displacement curve of the proof mass decreases with increasing displacement, for at least part of the force-displacement curve. This is the so-called anti-spring effect. The resonant frequency of oscillation of the proof mass is determined at least in part by the orientation of the device relative to the direction of the force due to gravity. The proof mass is capable of oscillating with a resonant frequency of 10 Hz or less. The proof mass has a mass of less than 1 gram.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: October 13, 2020
    Assignee: The University Court of the University of Glasgow
    Inventors: Paul Campsie, Giles Dominic Hammond, Richard Paul Middlemiss, Douglas John Paul, Antonio Samarelli
  • Patent number: 10801039
    Abstract: The present invention encompasses BTV and ASHV vaccines or compositions and methods of producing recombinant reassortant BTV and ASHV vectors and methods of vaccination against BTV and ASHV.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: October 13, 2020
    Assignees: THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW, Boehringer Ingelheim Animal Health USA Inc.
    Inventors: Massimo Palmarini, Sandro Filipe Nunes, Pascal Hudelet, Jean Christophe Audonnet
  • Publication number: 20200292459
    Abstract: A CMOS-based chip having one or more sensing modalities that are able independently to detect multiple metabolites present in a biological sample. The multiple sensing modalities may be provided at different locations with respect to the chip, whereby the chip can simultaneously detect a plurality of metabolites by measuring behaviour of a test material in the different locations. The chip may utilise paper as a transport mechanism for the sample. The paper either conveys the sample to the different locations or itself provides discrete testing zones in which different metabolites can be independently detected. With this technique, multiple metabolites may be measured in real time using a small scale point-of-care device.
    Type: Application
    Filed: May 23, 2018
    Publication date: September 17, 2020
    Applicant: The University Court of the University of Glasgow
    Inventors: David Robert Sime CUMMING, Samadahn PATIL, Mohammed AL-RAWHANI, Michael BARRETT, Dharmendra DHEEMAN, Chunxiao HU
  • Patent number: 10767153
    Abstract: A mechanical bioreactor for transferring vibrations to cell cultures for the purpose of stimulating various biological processes across a relatively large (relative to the amplitude of the vibrations) sample receiving surface. This bioreactor allows multiple samples to receive identical stimulation, which may enable the process to be significantly scaled up. The invention may be particularly applicable to nanoscale vibration amplitudes, where it is non-trivial to design a device that performs this function, because many materials exhibit natural deformation on a scale that would mask or inhibit transfer of nanoscale vibration energy.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: September 8, 2020
    Assignees: THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW, THE UNIVERSITY OF THE WEST OF SCOTLAND
    Inventors: Matthew Dalby, Habib Nikukar, Gabriel Pemberton, Adam Curtis, Stuart Reid, Peter Childs
  • Publication number: 20200249175
    Abstract: A CMOS-based chip having multiple sensing modalities that are able independently to detect multiple metabolites present in a sample. In particular, the chip provides multiple sensing modalities capable of performing detection within the same physical test volume, i.e. the chip can simultaneously detect a plurality of chemical reactions occurring in the test volume, where each chemical reaction yields a result that is independently detectable. The chip may comprise an optical sensor (e.g. photodiode) and a chemical sensor (e.g. pH sensor, embodied as an ISFET). With this technique, multiple metabolites may be measured in real time using a small scale point-of-care device.
    Type: Application
    Filed: May 23, 2018
    Publication date: August 6, 2020
    Applicant: THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW
    Inventors: David Robert Sime CUMMING, Chunxiao HU, Mohammed AL-RAWHANI, Boon Chong CHEAH
  • Publication number: 20200168659
    Abstract: A method of fabricating a field-effect transistor in which a native oxide layer is removed prior to etching a gate recess. The cleaning step ensures that the etch of the gate recess starts at the same time across an entire sample, such that a uniform gate recess depth and profile can be achieved across an array of field-effect transistors. This results in a highly uniform switch-off voltage for the field-effect transistors in the array.
    Type: Application
    Filed: June 1, 2018
    Publication date: May 28, 2020
    Applicant: The University Court of the University of Glasgow
    Inventors: David Robert Sime CUMMING, Chengzhi XIE, Vincenzo PUSINO
  • Publication number: 20200121731
    Abstract: Provided are nucleic acid constructs, Toxoplasma comprising same, pharmaceutical compositions comprising same and methods using same for delivering a protein-of-interest to a tissue-of-interest of a subject, such as the CNS and further treating a pathology which is treatable by administration of a therapeutic polypeptide in a central nervous system of the subject.
    Type: Application
    Filed: June 29, 2017
    Publication date: April 23, 2020
    Applicants: Ramat at Tel-Aviv University Ltd., The University Court of the University of Glasgow
    Inventors: Oded RECHAVI, Shahar BRACHA, Lilach SHEINER
  • Patent number: 10604852
    Abstract: The invention provides methods for producing hydrogen and oxygen, comprising the steps of: (i) oxidising a mediator at a working electrode to yield an oxidised mediator, and reducing protons at a counter electrode to yield hydrogen; and (ii) reducing an oxidised mediator at a working electrode to yield a mediator, and oxidising water at a counter electrode to yield oxygen, wherein the oxygen generation step is performed non-simultaneously to the hydrogen generation step, and the oxidised mediator of step (i) is used as the oxidised mediator of step (ii), or the mediator of step (ii) is used as the mediator of step (i), and the mediator has a reversible redox wave lying between the onset of the oxygen evolution reaction (OER) and the hydrogen evolution reaction (HER).
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: March 31, 2020
    Assignee: THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW
    Inventors: Leroy Cronin, Mark Symes
  • Publication number: 20200081566
    Abstract: This invention relates to a touch sensor having a layered structure, the layers including: a substrate; and a touch-sensitive layer formed of single-layer graphene and having a plurality of coplanar electrodes formed therein. Embodiments of the touch sensor are flexible and stretchable, making them suitable for use as an artificial skin. Further embodiments of the touch sensor are also capable of sensing pressure as well as touch. Further embodiments are substantially transparent and can therefore include a photovoltaic layer under the touch-sensitive layer which can provide a degree of energy autonomy. Further aspects of the invention provide prosthetic devices having such touch sensors forming a sensitive skin, and a method of manufacturing a touch sensor wherein interdigitated electrodes are cut in single-layer graphene by a blade-cutting process.
    Type: Application
    Filed: February 19, 2018
    Publication date: March 12, 2020
    Applicant: The University Court of the University of Glasgow
    Inventors: Ravinder DAHIYA, Carlos GARCIA NUÑEZ
  • Publication number: 20190151408
    Abstract: The Invention relates to materials and methods for the treatment of conditions associated with bacterial biofilms, intracellular bacterial infections and/or adherent-invasive Escherichia coli infections, including Crohns' disease. In particular, the invention relates to the use of colicins and bacteria producing colicins, for the treatment of such conditions.
    Type: Application
    Filed: January 31, 2019
    Publication date: May 23, 2019
    Applicant: THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW
    Inventors: Daniel WALKER, Karen SMITH
  • Patent number: 10258987
    Abstract: The present invention generally relates to the manipulation of fluids using acoustic waves such as surface acoustic waves. In some aspects, one fluid may be introduced into another fluid via application of suitable acoustic waves. For example, a fluid may be added or injected into another fluid by applying acoustic waves where, in the absence of the acoustic waves, the fluid cannot be added or injected, e.g., due to the interface or surface tension between the fluids. Thus, for example, a fluid may be injected into a droplet of another fluid. Other embodiments of the invention are generally directed to systems and methods for making or using such systems, kits involving such systems, or the like.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: April 16, 2019
    Assignees: President and Fellows of Harvard College, The University Court of the University of Glasgow
    Inventors: David A. Weitz, Thomas Franke
  • Patent number: 10248032
    Abstract: A cone-based polarizer includes a beam splitter including a front side (FS) and a back side (BS) part for receiving a first and a second beam portion, respectively. The FS part includes two prisms including parallel first and second FS hypotenuses, and the BS part includes two prisms including parallel first and second BS hypotenuses. A first TIR cone is on top and a second TIR cone is on a bottom of the beam splitter. The first and second TIR cones are aligned to have an essentially common cone axis direction and are configured to add a structured polarization upon retroreflecting. The first and second FS hypotenuses have a FS TIR interface in-between and are angled at about 45 degrees relative to the cone axis direction. The first and second BS hypotenuses have a BS TIR interface in-between and are angled at about 90 degrees relative to the FS hypotenuses.
    Type: Grant
    Filed: April 17, 2018
    Date of Patent: April 2, 2019
    Assignees: Gooch and Housego PLC, The University Court Of The University Of Glasgow
    Inventors: Peter Edward MacKay, Jonathan Gavin Ironside-Smith, Sonja Franke-Arnold, Neal Matthew Radwell
  • Patent number: 10128095
    Abstract: A method of treating a particle beam is disclosed, of interest in particular for mass spectrometry for 14C. A particle beam including positive ions is passed through a charge exchange cell containing a target gas. The target gas is electrically insulating at room temperature and pressure. At least some of the positive ions of the particle beam are converted to negative ions by interaction with the target gas. The particle beam incident at the charge exchange cell includes molecules and/or molecular ions which interact with the target gas to reduce the concentration of molecules as a result of repeated collisions with particles of the target gas. A corresponding mass spectrometry system is also disclosed.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: November 13, 2018
    Assignee: University Court of University of Glasgow
    Inventors: Stewart Freeman, Richard Shanks
  • Publication number: 20180321164
    Abstract: A new spectroscopic technique and corresponding spectrometer for molecules in which optical radiation is used to shift the rotational/nuclear-spin energy levels of freely rotatable sample molecules, and in which these shifts are detected using probing radiation. This technique enables the determination of individual polarizability components and/or combinations of these and/or information about the constitution of a sample that follows from these. In particular, it can reveal the enantiomeric constitution of a chiral sample whilst yielding a non-vanishing signal even for a racemate. The technique may find particular use in the analysis of molecules that are chiral by virtue of their isotopic constitution and molecules with multiple chiral centres.
    Type: Application
    Filed: November 4, 2016
    Publication date: November 8, 2018
    Applicants: THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW, MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSC HAFTEN E.V.
    Inventors: Robert P. CAMERON, Jörg B. GÖTTE, Stephen M. BARNETT
  • Patent number: 9962677
    Abstract: The invention provides a method for preparing a compound or a product having one or more characteristics that meet or exceed a user specification, the process comprising the step of selecting a first combination of chemical inputs, optionally together with physical inputs, and supplying those inputs to a reaction space, thereby to generate a first product; analyzing one or more characteristics of the product generated; comparing the one or more characteristics against a user specification; using a genetic algorithm selecting a second combination of chemical inputs, optionally together with physical inputs, wherein the second combination differs from the first combination, and supplying those inputs to the reaction space, thereby to generate a second product; analyzing one or more characteristics of the second product generated; comparing the one or more characteristics generated against the user specification; repeating the selecting and analyzing steps for further individual combinations of chemical and/or p
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: May 8, 2018
    Assignee: The University Court of the University of Glasgow
    Inventor: Leroy Cronin
  • Patent number: 9932582
    Abstract: The invention relates to the use of microRNA 29 and precursors and mimics thereof for the modulation of tendon injury and the biomechanical properties of tendon. In particular, the invention derives from the finding that synthesis of type 1 collagen in tenocytes is less sensitive to miR-29 than is synthesis of type 3 collagen, thus enabling the balance between the collagen subtypes to be modulated in favor of type 1 collagen, mitigating reduction in biomechanical properties during healing.
    Type: Grant
    Filed: January 14, 2015
    Date of Patent: April 3, 2018
    Assignee: The University Court of the University of Glasgow
    Inventors: Derek Stewart Gilchrist, Neal Lindsay Millar