Abstract: The computer-assisted moving eye campimetric device is a computer display of a moveable test grid having a central reference spot. The patient's eye is kept focussed on the spot by giving the patient the task of keeping the moving spot in a circle by operating a hand held mouse. With the patient's eye correctly focussed on the reference spot, target elements in the field of vision are successively illuminated and the patient reacts by pressing a button on the mouse. Failure to react indicates impaired vision at that point in the patient's visual field. The results are held in the computer memory and plotted out as a map of the patient's effective field of vision.

Abstract: The present invention relates to the location of biological cells 5 in a predetermined spatial disposition relative to each other on a solid non-biological substrate. According to the invention an extended generally planar surface of the substrate is provided with a plurality of surface discontinuities 4 at least partly defining cell adhesion enhanced and/or cell-adhesion orienting zones having a width of from 0.2 to 20 micrometers in a predetermined relation to each other and substantially spaced apart from each other. When a plurality of the cells 5 in a physiologically acceptable medium is brought into contact with said substrate surface cells attached to the substrate surface preferentially and/or in preferential orientations at said discontinuities 4.

Abstract: The present invention provides a method of preparing a substantially non-toxic immunogenic preparation of pertussis toxic comprising treatment of pertussis toxin with a carbodiimide. The preparation may be used for vaccination against whooping cough as well as making vaccines for use in immunization against whooping cough. Desirably the pertussis toxin is treated in the form of an intimate admixture with filamentous.

Abstract: The present invention provides an oculo-perimetric device for use in measuring the field of vision of a subject and comprises an extended area visual target 1 having a large plurality of generally regularly, angularly and/or radially, spaced apart individual target elements 2, disposed around a central reference target element 3 across substantially the whole of the area within a predetermined radial separation R from said reference target 3. The individual target elements 2 are provided with sequence indicating means 4 formed and arranged so as to define a visually discernible predetermined sequence for fixing of a subject's eye 5 on successive adjacent individual target elements 2. The central reference target element 3 is formed and arranged so as to be visually more prominent than the individual target elements 2.

Abstract: The device comprises a core containing nutrient and/or therapeutic material and/or other biologically active material and an insoluble rigid brittle skin enclosing the core. The skin is formed of a synthetic resin, and is arranged to require support of the core to maintain its integrity. The skin may be formed on the core by dipping the core in the liquified resin or by spraying liquified resin on the core.

Abstract: A thermoelectric alloy composition is described comprising from 5% to 95% silicon, from 95% to 5% Germanium, from 0.01% to 0.2% lead and from 0% to 0.2% tin, all percentages being atomic percentages. In a preferred composition at least 50% silicon and 50% Germanium is present with 0.03% to 0.1% lead and from 0 to 0.05% tin. Tin and lead in combination provide lower thermal conductivity and a greater figure of merit than with lead or tin alone. Other preferred compositions are provided and a thermoelectric material and a p-n coupling thermoelectric generator (10) incorporating the alloy is disclosed. The alloy composition provides high efficiency of power to heat loss and minimizes running costs.

Abstract: A heart valve prosthesis comprising an annular support frame for a plurality of flexible tissue valve components. The support frame has a plurality of spaced posts defining openings therebetween to permit a portion of each valve element to flex from an open position to a closed position. An annular sleeve, concentric with said support frame, is adapted to clamp a non-flexing portion of each valve element in operative position between the support frame and said sleeve.

Abstract: Microwave thermography apparatus comprises a signal-receiving aerial (2) which is sensitive to microwave radiation emanating from a body having a mean body temperature. A reference load (1) capable of being maintained at a chosen temperature (T.sub.O) and of emitting a thermal noise signal at microwave frequency corresponding to temperature T.sub.O, is connected to a receiver (3) the input impedance of which is matched to the impedance of reference load (1) by way of a 3-port non-reciprocal circulator (5). Aerial (2) is connected via a single-throw on/off microwave switch (6) to the input of receiver (3) through the other port of circulator (5). The connections to circulator (5), taken in circulation order, are reference load (1), aerial (2), receiver (3). Aerial (2) is preferentially designed to incorporate a tubular metallic waveguide (10) of circular cross-section dimensioned to support TE.sub.

Abstract: A low-temperature stage for use in an electron microscope comprises a main body (37), a holder (10) for a specimen mount, a heat exchanger (16) within the main body (37), conduit means (14, 18) for supplying coolant to the heat exchanger, a bar (22) of relatively large cross-section and relatively high thermal conductivity interconnecting the heat exchanger (16) and the specimen mount holder (10) to form a heat transfer path therebetween, and a support member (28) of relatively small cross-section and relatively low thermal conductivity interconnecting the specimen mount holder (10) and the main body (37), the support member (28) being a generally box-shaped member (28) disposed around said bar. An anti-contaminator for an electron microscope, comprising a metallic cryogenic shield (58), a tank (50) for holding a cryogenic liquid maintained at boiling point, and a thermal pathway (60) between the shield (58) and the tank (50).