Abstract: The invention provides methods to elicit an immune response with an immunomodulatory flagellin polypeptide having toll-like receptor 5 (TLR5) binding, and further comprising an ADCC targeting molecule.
Type:
Grant
Filed:
July 26, 2011
Date of Patent:
July 21, 2015
Assignees:
THE UNIVERSITY FOR SYSTEMS BIOLOGY, UNIVERSITY OF WASHINGTON
Inventors:
Alan Aderem, Fumitaka Hayashi, Kelly D. Smith, David M. Underhill, Adrian Ozinsky