Patents Assigned to The University of Alberta
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Publication number: 20130228525Abstract: A flocculating agent that comprises a complex of a metal salt and multiple strands of a temperature sensitive polymer. A process for separating coal fines from an aqueous liquid using a flocculent having a critical flocculation temperature, said critical flocculation temperature being the temperature below which flocculent is hydrophilic and forms floccules with fines and above which the flocculent is hydrophobic, which comprises adding to the aqueous liquid an effective amount of the flocculent at a temperature below the critical flocculent flocculation temperature of the flocculent to cause generation of floccules, said comprising at least a metal complex including a metal salt and a water soluble polymer, separating (for example filtering) floccules from the aqueous liquid, then heating the floccules to a temperature above the critical flocculation temperature of the flocculent to expel water from the floccules to create a solids and expelled water, and separating the expelled water from the solids.Type: ApplicationFiled: March 4, 2013Publication date: September 5, 2013Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTAInventor: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
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Publication number: 20130210618Abstract: A hydrogen absorbing and desorbing material formed by co-deposition of magnesium with a catalyst for the kinetic absorption and desorption of hydrogen. A hydrogen absorbing and desorbing material formed of an alloy of magnesium with a catalyst for the kinetic absorption and desorption of hydrogen in which the catalyst for the kinetic absorption and desorption of hydrogen forms a dispersed amorphous or nanocrystalline phase in the magnesium. A hydrogen absorbing and desorbing material having a catalytic surface formed by a process comprising the steps of depositing a layer of tantalum on the hydrogen absorbing and desorbing material and depositing a layer of palladium on the layer of tantalum. A hydrogen absorbing and desorbing material comprises a multilayer film having at least two layers of magnesium and at least two layers of catalyst for the kinetic absorption and desorption of hydrogen, in which the multilayer film comprises alternating layers of magnesium and catalyst.Type: ApplicationFiled: August 18, 2011Publication date: August 15, 2013Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTAInventors: David Mitlin, Beniamin Zahiri, Mohsen Danaie, Babak Shalchi Amirkhiz, XueHai Tan, Erik Luber, Christopher Harrower, Peter Kalisvaart
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Publication number: 20130211066Abstract: Provided in the following specification are precursors or synthons that are useful for the synthesis of various arabinose based chemical and radiochemical derivatives of nitroimidazole-containing azomycin arabinosides, such as radioiodinated 1-#-D-(5-deoxy-5-[I*]-iodoarabinofuranosyl)-2-nitroimidazole (*IAZA), and radiofluorinated 1-#-D-(5-deoxy-5-[18F]-iodoarabinofuranosyl)-2-nitroimidazole (18FAZA). Such compounds are useful in imaging, therapy, or radiotherapy. Further, various syntheses of said precursors/synthons and the incorporation of said precursors/synthons into kits is provided. The precursors/synthons provided herein allow for an improved and facile manufacturing process for nitroimidazole-containing azomycin arabinosides.Type: ApplicationFiled: June 27, 2011Publication date: August 15, 2013Applicants: ALBERTA HEALTH SERVICES, THE GOVERNORS OF THE UNIVERSITY OF ALBERTAInventors: Piyush Kumar, Leonard Wiebe, Alexander McEwan
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Publication number: 20130205910Abstract: A new approach for building a stress-sensing rosette capable of extracting the six stress components and the temperature is provided, and its feasibility is verified both analytically and experimentally. The approach can include varying the doping concentration of the sensing elements and utilizing the unique behaviour of the shear piezoresistive coefficient (?44) in n-Si.Type: ApplicationFiled: November 25, 2011Publication date: August 15, 2013Applicant: The Governors of the University of AlbertaInventors: Hossam Mohamed Hamdy Gharib, Walied Ahmed Mohamed Moussa
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Patent number: 8507203Abstract: The invention is directed to aptamers, methods and kits comprising same for detecting Streptococcus pyogenes. The method of screening a subject for Streptococcus pyogenes involves obtaining a body sample from the subject; contacting the sample or a bacterial culture of the sample with an aptamer or a panel of aptamers specific to S. pyogenes; and detecting the presence or absence of S. pyogenes in the sample or the bacterial culture, wherein binding of the aptamer is indicative of the presence of S. pyogenes.Type: GrantFiled: March 29, 2012Date of Patent: August 13, 2013Assignee: The Governors of the University of AlbertaInventors: X. Chris Le, Camille Hamula, Xing-Fang Li
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Patent number: 8501995Abstract: The present invention provides new ?-phenylethylidenehydrazine derivatives, processes for preparing them and their use as pharmaceutical compostions.Type: GrantFiled: July 9, 2010Date of Patent: August 6, 2013Assignee: The Governors of the University of AlbertaInventors: Glen Baker, Edward Knaus
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Patent number: 8503849Abstract: A method of forming a waveguide is disclosed, as well as the waveguide itself. A multilayer stack of light guiding layers is formed, and the multilayer stack is delaminated between light guiding layers to form a waveguide between the light guiding layers. The multilayer stack is delaminated in a patterned region between light guiding layers. Here a new approach is described, wherein hollow microchannels forming a Bragg waveguide assembly are fabricated by controlled formation of thin film delamination buckles within a multilayer stack. A hollow waveguide is formed by alternating layers of the multilayer stack forming light guiding surfaces. The hollow waveguide is formed between layers that delaminate from each other, as for example under applied stress to one or more of the layers. The multi-layer stack may be formed of alternating layers of low and high index of refraction materials, as for example forming omni-directional dielectric reflectors.Type: GrantFiled: March 27, 2008Date of Patent: August 6, 2013Assignee: The Governors of the University of AlbertaInventor: Raymond George Decorby
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Patent number: 8501154Abstract: The present invention is directed to fructose-based radiopharmaceuticals, pharmaceutical compositions comprising same, precursors and methods for preparing same, and methods of using same for diagnostic imaging of cancer cells and non-imaging tracer studies.Type: GrantFiled: September 19, 2012Date of Patent: August 6, 2013Assignee: The Governors of the University of AlbertaInventors: Chris Cheeseman, Frederick West, Tina Grant, Brendan Trayner, John Mercer, Andrei Manolescu
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Patent number: 8498323Abstract: A novel ultra-wide bandwidth receiver structure dubbed the “zonal” receiver is proposed to detect time-hopping ultra-wide bandwidth signals in multiple access interference channels. The zonal receiver outperforms the conventional matched filter ultra-wide bandwidth receiver and the recently proposed soft-limiting ultra-wide bandwidth receiver when only MAI is present, or AWGN is negligible compared to MAI. In more practical mixed MAI-plus-AWGN environments, the zonal ultra-wide bandwidth receiver achieves better performance than the conventional matched filter ultra-wide bandwidth receiver, the recently proposed soft-limiting ultra-wide bandwidth receiver, and the recently proposed adaptive threshold soft-limiting ultra-wide bandwidth receiver. In multipath fading UWB channels, a new Rake receiver based on the zonal UWB receiver design has been proposed, this new Rake receiver can achieve better BER performance than the conventional matched filter based Rake receiver.Type: GrantFiled: March 7, 2008Date of Patent: July 30, 2013Assignee: The Governors of the University of AlbertaInventors: Norman C. Beaulieu, Hua Shao
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Publication number: 20130178515Abstract: Taxanes are widely used in the treatment of breast cancer, although there are currently no validated predictive markers for taxane responsiveness. While the mechanism by which taxanes induce mitotic arrest is well documented, the signaling pathway that links mitotic arrest to cell death, is ill-defined. As described herein, the BH3-only protein Bad and Bik are prognostic indicators for overall survival after adjuvant taxane chemotherapy and a predictive marker for taxane responsiveness.Type: ApplicationFiled: November 19, 2010Publication date: July 11, 2013Applicants: ALBERTA HEALTH SERVICES, THE GOVERNORS OF THE UNIVERSITY OF ALBERTAInventors: Ing Swie Goping, John R. Mackey, D. Alan Underhill
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Publication number: 20130165333Abstract: Described herein are the preparation and use of novel bromo-phosphonomethylphenylalanine amino acid derivatives (BrPmp) and BrPmp-containing peptides as specific, irreversible protein tyrosine phosphatase inhibitors, which are suitable for application in peptide synthesis. These derivatives are particularly advantageous since their synthesis is both easy and scalable, and they are suitable for peptide synthesis. The BrPmp derivatives described herein can be appropriately protected to allow for solid phase peptide synthesis (SPPS) and incorporation into peptides for preparation of protein tyrosine phosphatase inhibitors and inhibitor libraries. The peptides and peptide libraries can be used to identify new protein tyrosine phosphatase specific sequences and profile protein tyrosine phosphatase activity in cell lysates, diagnostic samples and biopsy samples.Type: ApplicationFiled: March 3, 2011Publication date: June 27, 2013Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTAInventors: Christopher Warren Cairo, Naresh Singh Tulsi, Alan Michael Downey
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Publication number: 20130160169Abstract: The invention is directed to isolated polynucleotide and polypeptides of the CoD5, CoD6 and CoE6 genes from Conidiobolus obscurus, the CtE6 gene from Conidiobolus thromboids, and the PgDesX gene from Puccinia graminis; nucleic acid constructs, vectors and host cells incorporating the polynucleotide sequences; and methods of producing and using same.Type: ApplicationFiled: December 19, 2011Publication date: June 20, 2013Applicants: THE UNIVERSITY OF SASKATCHEWAN, THE GOVERNORS OF THE UNIVERSITY OF ALBERTAInventor: Xiao QIU
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Publication number: 20130157278Abstract: The present invention provides for a novel system and method for amplification and detection of nucleic acids within a microfluidic device wherein multiple nucleotides capable of priming PCR are present within the system and substantially sequestered within separate hydrogel posts therein.Type: ApplicationFiled: August 29, 2011Publication date: June 20, 2013Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTAInventor: Alexey Atrazhev
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Publication number: 20130149709Abstract: The present invention provides for a novel system and method for amplification and detection of nucleic acids within a miniaturized device.Type: ApplicationFiled: July 8, 2011Publication date: June 13, 2013Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTAInventors: Alexey Atrazhev, Jason Acker
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Publication number: 20130150556Abstract: The invention is directed to a method of producing deamidated barley proteins by extracting protein from barley using an alcohol or alkaline; treating the extracted protein with an alkaline or acidic solution for a sufficient time and temperature for partial deamidation; and recovering partially deamidated protein from the solution. The partially deamidated protein has improved functional properties with respect to solubility, and emulsifying and foaming properties at acidic and neutral pHs compared to those of a non-deamidated protein.Type: ApplicationFiled: July 18, 2011Publication date: June 13, 2013Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTAInventor: Lingyun Chen
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Patent number: 8464126Abstract: Two hybrid message decoders for low-density parity-check (LDPC) codes are proposed. One decoder uses a posteriori probability ratio (APPR) and a posteriori probability difference (APPD), and the other decoder uses a logarithm a posteriori probability ratio (LAPPR) and a logarithm a posteriori probability difference (LAPPD) as hybrid message. Since the variable node and check node processing can be readily done using APPR and APPD, respectively, the proposed decoders have lower complexity than the conventional decoder that uses LAPPR only as a message.Type: GrantFiled: August 19, 2008Date of Patent: June 11, 2013Assignee: The Governors of the University of AlbertaInventors: Young Gil Kim, Norman C. Beaulieu
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Publication number: 20130144369Abstract: A flexible-base electrode array for implantation within neural tissue, method of making the electrode array and use thereof, is provided. A surrogate neural tissue, method of making same and use thereof, is further provided. The use of the present flexible-base electrode array for implantation into the surrogate neural tissue for stimulation or recording neural activity, wherein the array is biocompatible with the surrogate tissue.Type: ApplicationFiled: October 22, 2012Publication date: June 6, 2013Applicant: The Governors of the University of AlbertaInventor: The Governors of the University of Alberta
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Patent number: 8458811Abstract: An all-metal microdevice or nanodevice such as an atomic force microscope probe is manufactured from a copper-hafnium alloy thin film having an x-ray amorphous microstructure.Type: GrantFiled: March 25, 2011Date of Patent: June 4, 2013Assignees: The Governors of the University of Alberta, The Regents of the University of CaliforniaInventors: Erik J. Luber, Colin Ophus, David Mitlin, Brian Olsen, Christopher Harrower, Velimir Radmilović
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Publication number: 20130136860Abstract: A method of fabricating carbon nanotube arrays (CNTA) on an oxide catalyst layer is disclosed. In one embodiment, the oxide catalyst is a metal oxide. The metal oxide may be deposited on a substrate used as a support. The CNTA is grown on the oxide catalyst layer under conditions promoting CNT growth. CNT growth is dependent on temperature, concentration of oxidizing molecules and carbon availability. One embodiment of the method comprises depositing an oxide catalyst layer on the substrate, heating the catalyst layer at certain rates to the target temperatures, adding oxidation molecules for the pretreatment of the oxide catalyst layer, and growing the array on the substrate. The oxide catalyst layer may comprise a group VIII element.Type: ApplicationFiled: August 12, 2011Publication date: May 30, 2013Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTAInventors: Weixing Chen, Xinwei Cui
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Patent number: 8450127Abstract: Visible and infrared light sources on silicon that have several attractive properties with respect to integrated optics. First, the devices are operational at room temperature and strictly require no thermal processing in their synthesis (although low temperature annealing can be used to form Ohmic contacts). These devices could therefore be included at any stage of chip fabrication. The special ease of synthesis of these silicon LEDs enables simple fabrication of surface structures such as patterned emitters and photonic crystal surfaces that enhance light emission in the forward direction. The LEDs are color-switchable—by reversing the current one can switch from infrared emission to visible emission. The lifetime of the luminescence is much shorter than the standard carrier recombination time in silicon, suggesting direct modulation of the emitted light.Type: GrantFiled: September 10, 2008Date of Patent: May 28, 2013Assignee: The Governors of the University of AlbertaInventors: Al Meldrum, Sulan Kuai