Patents Assigned to The University of Antwerp
  • Epidermal differentiation factor
    Patent number: 7071312
    Abstract: A human epidermal differentiation factor polypeptide and DNA (RNA) encoding such polypeptide and procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for treating and/or preventing skin diseases. Diagnostic assays for detecting mutations in a nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention are also disclosed.
    Type: Grant
    Filed: August 11, 2004
    Date of Patent: July 4, 2006
    Assignees: The University of Antwerp, Human Genome Sciences, Inc.
    Inventors: Jian Ni, Ping Feng, Patrick J. Dillon, Reiner L. Gentz, Joseph Merregaert, Patrick Smits
  • Epidermal differentiation factor
    Publication number: 20060063922
    Abstract: A human epidermal differentiation factor polypeptide and DNA (RNA) encoding such polypeptide and procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for treating and/or preventing skin diseases. Diagnostic assays for detecting mutations in a nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention are also disclosed.
    Type: Application
    Filed: November 8, 2005
    Publication date: March 23, 2006
    Applicants: The University of Antwerp, Human Genome Sciences, Inc.
    Inventors: Jian Ni, Ping Feng, Patrick Dillon, Reiner Gentz, Joseph Merregaert, Patrick Smits
  • Human extracellular matrix-1
    Publication number: 20050227282
    Abstract: A human ECM-1 polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for stimulating the differentiation in growth of osteoblasts and osteoclasts, which may be used to promote the healing of bone fractures and de novo bone formation, for osteoporosis, for and to promote angiogenesis. Antagonists to the polypeptide of the present invention are also disclosed which may be utilized to treat osteodystrophy, osteohypertrophy, osteoma, osteoblastoma and cancers. Diagnostic assays for identifying mutations in nucleic acid sequence encoding a polypeptide of the present invention.
    Type: Application
    Filed: June 2, 2005
    Publication date: October 13, 2005
    Applicants: Human Genome Sciences, Inc., The University of Antwerp
    Inventors: Jian Ni, Ping Feng, Patrick Dillon, Reiner Gentz, Joseph Merregaert, Patrick Smits
  • Epidermal differentiation factor
    Publication number: 20050009141
    Abstract: A human epidermal differentiation factor polypeptide and DNA (RNA) encoding such polypeptide and procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for treating and/or preventing skin diseases. Diagnostic assays for detecting mutations in a nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention are also disclosed.
    Type: Application
    Filed: August 11, 2004
    Publication date: January 13, 2005
    Applicants: The University of Antwerp, Human Genome Sciences, Inc.
    Inventors: Jian Ni, Ping Feng, Patrick Dillon, Reiner Gentz, Joseph Merregaert, Patrick Smits