Abstract: The her-1 gene of Caenorhabditis elegans has been isolated and sequenced. The her-1 gene encodes an amino acid sequence which induces male differentiation. Methods for recombinantly producing the her-1 protein and for transforming plants, bacteria and fungi with the her-1 gene to express the her-1 protein are disclosed.

Abstract: This invention provides a multipass Solc filter which utilizes liquid crystal variable retarders to provide high resolution and tunability. The Solc polarization-interference effects are used synergistically with the Fabry-Perot cavity resonances. The cavity comprises a central retarder, two quarter wave plates, and an optional isotropic spacer. The central retarder or the isotropic spacer can include liquid crystal cells to provide tuning of the Solc envelope or the cavity resonances respectively. In one embodiment the variable retarder is a three element quarter-half-quarter device with a liquid crystal electro-optically rotatable half-wave plate. Reflection mode configurations are introduced wherein, because of the bilateral symmetry of the Solc filter, it is possible to use only half of the intracavity elements. Criteria for designing filter parameters to meet resolution, out-of-band discrimination, and tuning range requirements are provided.

Abstract: Improved methods for the GC/MS analysis of sulfhydryl amino acids and methylmalonic acids in samples of body fluids are provided. Additionally a method for combined assay of sulfhydryl amino acids particularly total homocysteine and combined creatine/creatinine levels in samples of body fluids provided. The information provided by the methods described is useful in the detection of the presence of cobalamin or folate deficiencies in individuals and in distinguishing between the two deficiencies.

Abstract: Derivatized molybdenum-sulfide dimers of the general formula [(C.sub.5 R.sub.5 Mo).sub.2 (.mu.-S).sub.4-x (.mu.-SR).sub.x ].sup.n are utilized in the solid state, incorporated in permselective membranes and in aqueous solution as chemical specific complexing agents in various separation processes.

Abstract: The present invention describes a perfluorinated ionomer membrane having a improved transport characteristics. A surfactant species is added to a polymer mixture prior to film casting. The resulting membranes have a measurably altered membrane microstructure and improved transport characteristics over prior art membranes. The present invention describes the method of producing the improved membranes. The membranes of the present invention are useful in a number of separation processes, including the separation of NH.sub.3 from gaseous and liquid mixtures, in the production of NaOH and Cl.sub.2 gas from the electrolytic dissolution of NaCl, in the separation of toxic and radioactive metals from aqueous streams, and in solid polymer electrolyte H.sub.2 /O.sub.2 fuel cells.

Abstract: Derivatized molybdenum-sulfide dimers of the general formula [(C.sub.5 R.sub.5 Mo).sub.2 (.mu.-S).sub.4-x (.mu.-SR).sub.x ].sup.n are utilized in the solid state, incorporated in permselective membranes and in aqueous solution as chemical specific complexing agents in various separation processes.

Abstract: Apparatus for time modifying, or expanding, a serial optical signal that comprises a plurality of light pulses located in bit cells. A plurality of light reflectors establish a plurality of optical delay paths, one path for each light pulse. Each path provides a progressively greater delay time. A scanner operates in synchronism with the bit cell frequency of the optical signal, and sequentially switches each light pulse to the input of a corresponding delay path. A serial output is associated with the output of the plurality of delay paths, and operates to assemble the output pulses into an output optical signal having a like plurality of light pulses. The time separation or bit cell frequency of the output optical signal is greater than the bit cell frequency of the input optical signal.

Abstract: Wall coverings for anechoic chambers are disclosed having an array of lossy pyramid cone material mounted on multiple backing layers of absorbing material. The number of backing layers to be used, their physical dimension (thickness) and their material properties (conductivity and permittivity) are selected so as not to modify the high frequency (UHF) behavior of the pyramid structure, while at the same time providing a greatly reduced low frequency (VHF) reflection coefficient for the composite absorbing wall. The physical dimension and the material properties of each of the multiple backing layers are selected by a constrained nonlinear optimization data processing procedure or method. The optimization method utilizes known S parameters of the pyramid array, and either known properties of the backing layers, or constrained backing layer properties that are defined by the wall designer.

Abstract: A method of forming thallium, barium, calcium, copper oxide films with smooth surfaces and chemical uniformity by sequentially depositing layers and annealing in the absence of a separate source of Tl.

Abstract: Provided is a method for treating Type I diabetes in mammals utilizing certain phenol and benzamide compounds.

Abstract: A surface emitting semiconductor laser includes a body of a semiconductor material having a pair of opposed surfaces and a plurality of active regions stacked one on the other between the surfaces. Each of the active regions includes a p-type conductivity layer, an n-type conductivity layer and an active layer therebetween. The active layer can either be intrinsic or a quantum well. The p-type and n-type layers are doped to provide a tunneling junction between the layers of adjacent active regions. The active layers of the active regions are spaced apart a multiple of one-half a wavelength to provide distributed feedback. Contacts are on the surfaces of the body with one of the contacts having an opening therethrough through which a generated light beam can emerge.

Abstract: Discretely and continuously tunable single and multiple-stage polarization interference filters employing chiral smectic liquid crystal cells as electronically rotatable retarders are provided. Discretely tunable filters of this invention include those which employ bistable surface-stabilized ferroelectric liquid crystal cells. Continuously tunable filters of this invention include those that employ chiral smectic A ferroelectric liquid crystal cells. Single stage filters include fixed birefringent elements in combination with chiral smectic liquid crystal cells and multiple stage filters can include only chiral smectic liquid crystal cells or can include chiral smectic liquid crystal cells in combination with fixed birefringent elements. Blocking filters useful for color generation and color displays are also provided. The FLC filters provided can be temporally multiplexed.

Abstract: The present invention provides optical polarization interference filters which employ chiral smectic liquid crystal (CSLC) cells as electronically rotatable retarders. The filters of the present invention are improved in that they are optimized for increased spectral discrimination, uniqueness of spectral outputs and efficient use of CSLC elements. The filters of the present invention include improved single and multiple stage filters. Improved discretely tunable and continuously tunable filters are provided. With respect to filters having one or more stages that contain a series of birefringent elements which are either fixed birefringent elements or active CSLC cells, this invention provides designs which optimize the number of pure spectral outputs which are unique. This optimization relates to the relative order of elements in a stage, the pattern of switching of the active CSLC cells, and the retardations of the CSLC cells in a stage.

Abstract: Method for specifically cleaving a single stranded DNA molecule. The method includes providing an RNA molecule having a deoxyribonuclease activity independent of any protein, and contacting that RNA molecule with the single stranded DNA molecule to cause the single stranded DNA molecule to be cleaved.

Abstract: A self-powered liquid crystal spatial light modulator is disclosed having a pair of spaced transparent glass plates, on each plate of which a transparent electrically conductive film is coated so as to be in confronting relation. A voltage/current generating, photovoltaic/photodiode, light sensitive layer is coated onto one of the conductive films. A liquid crystal layer is confined between the other conductive film and the light sensitive layer. A shorting circuit element connects the two conductive films. This shorting circuit element may be internal or external to the spatial light modulator. A pixel area of the spatial light modulator is addressed by a beam of light that illuminates the pixel area and operates to activate a corresponding area of the light sensitive layer. The voltage/current that is generated in this area of the light sensitive film causes a current to flow through the shorting circuit element, to thereby activate, switch or charge the corresponding area of the liquid crystal layer.

Abstract: Provided is a method for treating Type I diabetes in mammals utilizing certain aryl-substituted rhodanine derivatives.

Abstract: In a semiconductor device, a thin, synthetic diamond film (i.e. a man made film) enhances the transfer of heat from a semiconductor circuit chip to a cooling medium. The heat generating semiconductor circuit chip is located in efficient thermal transfer engagement with one surface of a synthetically deposited diamond film. The opposite surface of the diamond film forms the bottom wall of a cavity that contains a cooling medium. In one embodiment of the invention, the cavity is formed by depositing the diamond film on the surface of a silicon substrate, and then etching the silicon substrate to form an open-top cavity having side walls that comprise the silicon substrate, and having a bottom wall that comprises the diamond film. In a second embodiment of the invention, the open-top cavity is formed by an apertured silicon preform that is bonded to the diamond film. A capping member closes the top of the cavity. A cooling medium is placed within the cavity a fluid cooling medium may be circulated.

Abstract: Liquid crystal and ferroelectric liquid crystal compounds having core moieties based on nicotinic acid and having the general formula: ##STR1## where A is N or N--O and where R.sub.1 and R.sub.2, independently of one another, are straight chain or branched alkyl groups having from 1 to 20 carbons are provided. Ferroelectric liquid crystals of the present invention include those compounds in which one of R.sub.1 or R.sub.2 are chiral nonracemic groups. The pyridines and pyridine n-oxides or the present invention are useful as components of liquid crystal materials and certain of these compounds are useful as components of ferroelectric liquid crystal materials.

Abstract: An improved basal nutrient medium MCDB 120 for the clonal growth of human muscle satellite cells (HMSC) is described. In addition, a serum-free supplement for the clonal growth of HMSC containing serum albumin, dexamethasone, fetuin epidermal growth factor and insulin. Combination of MCDB 120 and the serum-free supplement results in a serum-free medium for growth of HMSC. The serum-free supplement can also be used with other basal nutrient media such as MCDB 131M for growth of HMSC. Addition of 5% dialyzed fetal bovine serum to the serum-free media described results in semi-defined media which allows significantly improved growth of HMSC.

Abstract: A semiconductor optoelectronic device provides full duplex data communication over a single optical fiber. The semiconductor device comprises a unitary P-N light emitting portion and an N-I-P photodiode portion. The light emitting portion and the photodiode portion share a common electrode for connection to operating voltage sources. The second electrode of the light emitting portion contains a window that is associated with one end of the optical fiber. A source of operating voltage for the light emitting portion is connected to the common electrode, and through data controlled switch means and a first resistance means to the second electrode of the light emitting portion. A source of operating voltage for the photodiode portion is connected to the common electrode, and through a second resistance means to a second electrode of the light emitting portion. Differential amplifier means is connected to receive the voltage developed across the first and second resistance means.