Abstract: A heat engine including a compressor, an expander, a reactor in which first and second reactants in a working fluid can react with each other, the reactor arranged between the compressor and the expander, and a condenser for condensing a gas in the working fluid, the condenser arranged between the expander and the compressor. There is also provided a method of operating a heat engine.

Abstract: An apparatus and method for imaging using microwave or terahertz radiation are described. The apparatus comprises: a cell comprising a vapour of atoms; one or more laser beams propagating through said cell, said one or more laser beams defining a sensing region in said cell; an imaging beam for illuminating an object receiving area for receiving an object to be imaged, said imaging beam comprising microwave or terahertz radiation; an imaging system for focusing the imaging beam to form, in use, an image of said object at said sensing region in said cell; wherein respective frequencies of said one or more laser beams and said imaging beam are such that at least some of said atoms, when subjected to radiation of both said one or more laser beams and said imaging beam, are excited to a final excited state which decays to a lower energy state by emission of optical fluorescence.

Abstract: A thermally activated delayed fluorescence (TADF) molecule comprising: a central electron donor moiety, wherein the central electron donor moiety is formed of a conjugated multi-ring system comprising three nitrogen atoms; and three electron acceptor moieties, each bonded to the central electron donor moiety via one of the three nitrogen atoms, wherein at least one of the three electron acceptor moieties is twisted relative to the central electron donor moiety defining a torsion angle in a range 40° to <90° whereby the TADF molecule has a photoluminescence quantum yield of >60% and a rate of reverse intersystem crossing from a lowest excited triplet state to a lowest excited singlet state of at least 1×10 s?1.

Abstract: The invention relates to compounds of formula (I), and pharmaceutical uses thereof. Particular aspects of the invention relate to methods of synthesising the compounds and the use of those compounds in treating, ameliorating, or preventing a microbial infection.

Abstract: A method for preparing a cyclic peptide, derivative or analogue thereof is described. The method comprises contacting a peptide, derivative or analogue thereof with a fluoro-heteroaromatic compound to cyclise the peptide, derivative or analogue thereof.

Abstract: The invention provides a coating which exhibits fast oleophobic-hydrophilic switching behaviour with, for example, equilibration of high oil contact angle (hexadecane=80°) and low water contact angle (<10°) values which occur within 10 s of droplet impact. These optically transparent surfaces display excellent anti-fogging and self-cleaning properties. The magnitude of oleophobic-hydrophilic switching can be further enhanced by the incorporation of surface roughness and in one embodiment the coating is applied to a surface in the form of a mesh in order to form an effective filter.

Abstract: The invention relates to compounds of formula (I), and pharmaceutical uses thereof. Particular aspects of the invention relate to methods of synthesizing the compounds and the use of those compounds in treating, ameliorating, or preventing a microbial infection.

Abstract: A method for chemically modifying a peptide, derivative or analogue thereof is described. The method comprises contacting a peptide, derivative or analogue thereof with a fluoro-heteroaromatic compound to activate the peptide, derivative or analogue thereof. The activated peptide, derivative or analogue thereof is then contacted with a nucleophile or base to create a chemically modified peptide, derivative or analogue thereof.

Abstract: A method for increasing production of ethanol in an ethanologenic cell using an autoinducer molecule, for example, AI-2.

Abstract: A method of generating a stereoscopic image is disclosed. The method includes defining at least two, three or more regions in a scene representing a region of interest, a near regions and/or a far region. This is followed by forming an image pair for each region, this image pair containing the information relating to objects in or partially in their respective region. The perceived depth within the regions is altered to provide the idea or best perceived depth within the region of interest and acceptable or more compressed perceived depths in the other regions. The image pairs are then mapped together to form a display image pair for viewing on a display device.

Abstract: We describe the functional cloning and the use of a non-fungal inositol phosphoryceraminde synthase (IPC synthase) in a screening assay for the identification of agents that target and antagonize the activity of IPC synthase.