Patents Assigned to The University of Hong Kong
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Publication number: 20150045238Abstract: The present invention provides a method for assessing the presence and risk of developing type 2 diabetes, cancer of all sites, or cardiovascular disease in a subject by detecting sequence variation in one or more genes such as carboxypeptidase E (CPE) and insulin degradation enzyme (IDE). A kit, array, and device useful for such a method are also provided. In addition, the present invention provides a method for treating type 2 diabetes, cancer of all sites, or cardiovascular disease in patients who have been tested and shown to have the pertinent genetic variations.Type: ApplicationFiled: January 28, 2013Publication date: February 12, 2015Applicant: The Chinese University of Hong KongInventors: Juliana Chung-Ngor Chan, Wing-Yee So, Ronald Ching-Wan Ma
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Patent number: 8953168Abstract: An optical sensing device including a source unit configured to generate a polychromatic light beam containing p-polarized beam and s-polarized beam; an interferometric unit configured to introduce birefringent retardation for generating optical path difference between the p-polarized beam and the s-polarized beam; a SPR sensing unit configured to receive both p-polarized beam and s-polarized beam and induce a SPR effect to the p-polarized beam associated with a target sample; and a detection unit for detecting target sample characteristics by obtaining an interference spectrum of the p-polarized beam and the s-polarized beam from the SPR sensing unit.Type: GrantFiled: June 8, 2012Date of Patent: February 10, 2015Assignees: City University of Hong Kong, The Chinese University of Hong KongInventors: Shu Yuen Wu, Ho Pui Ho, Chi-man Lawrence Wu, Siu-pang Ng
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Patent number: 8952617Abstract: The present invention provides a passive LC ballast and an associated method of manufacturing a passive LC ballast for use with any one of a plurality of high voltage discharge lamps. The passive LC ballast has an inductance and a capacitance selected in accordance with one of a set of one or more inductance-capacitance pairs. Each inductance-capacitance pair defines a respective inductance and a respective capacitance such that, when the inductance and the capacitance of the passive LC ballast is selected in accordance with any one of the inductance-capacitance pairs and the passive LC ballast is used with any one of the lamps, the lamp operates between respective minimum and maximum lamp powers of the lamp.Type: GrantFiled: November 3, 2009Date of Patent: February 10, 2015Assignee: City University of Hong KongInventors: Ron Shu Yuen Hui, Wai Man Ng, Deyan Lin
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Patent number: 8945536Abstract: Disclosed is a cell sheet for tissue repair and bio-artificial tissue engineering. The cell sheet comprises treated stem cell embedded in its self-secreted extracellular matrix (ECM) and formed a cell sheet. The cell sheet is formed by isolating the stem cell, expanding the stem cell and treating the stem cell with biological factors or factors leading to the production of biological factors, to induce its differentiation, production of extracellular matrix and formation of a cell sheet in vitro. The cell sheet is used as a bioactive material or as an acellular material for the promotion of tissue repairs or used to form a bio-artificial organ for tissue replacement. The cell sheet of the present invention eliminates the need to use scaffolds for cell delivery. The cell sheet facilitates in vivo cell transplantation and provides some tensile mechanical strength for bearing early mechanical load during tissue repair.Type: GrantFiled: January 20, 2012Date of Patent: February 3, 2015Assignee: The Chinese University of Hong KongInventors: Po Yee Pauline Lui, Ming Ni, Yunfeng Rui
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Publication number: 20150028824Abstract: A universal serial bus (USB) power supply is disclosed as including a main body (12) and a cable (24) releasably connectable with each other, the main body (12) being releasably connectable to a direct current (DC) power source and having a USB receptacle (20) electrically connectable with the DC power source. The cable (24) includes a USB plug (26) releasably connectable with the USB receptacle (20) to establish electrical connection and data communication there-between and a connector (30) electrically connected with the USB plug (26). The power supply is operable in a detached mode in which the main body (12) is out of connection with the cable (24) and in an attached mode in which the main body (12) is releasably connected with the cable (24). The power supply is adapted, when in the attached mode, to automatically change the voltage of a DC power output from the connector (30).Type: ApplicationFiled: July 29, 2013Publication date: January 29, 2015Applicant: City University Of Hong KongInventors: Chung Fai Norman TSE, Shu Hung Henry CHUNG, Yau Chung John CHAN
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Publication number: 20150027555Abstract: A microfluidic platform including a microfluidic layer and a contact layer. The microfluidic layer is embedded with a microfluidic structure including a micro-channel and a fluidic sample contained in the micro-channel. The contact layer is able to be attached to the microfluidic layer, and includes a first heater for heating a first area of the microfluidic structure to a first temperature and a second heater for heating a second area of the microfluidic structure to a second temperature. The microfluidic layer and the contact layer rotate together during operation. A method for controlling a sample in the micro-channel of the microfluidic structure.Type: ApplicationFiled: September 10, 2012Publication date: January 29, 2015Applicants: THE CHINESE UNIVERSITY OF HONG KONG, NANYANG TECHNOLOGICAL UNIVERSITY, HOSPITAL AUTHORITYInventors: Qiu Lan Chen, Ho Pui Ho, Siu Kai Kong, Patrick Kwok Leung Kwan, Yiu Wa Kwan, Ho Chin Kwok, Ping Shum, Yick Keung Suen, Shu Yuen Wu, Alice Kar Lai Yang, Jun Qiang Zhou
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Patent number: 8940656Abstract: Disclosed are a photocatalyst of CoP2 loaded red phosphorus, a preparation method thereof, and a method for photocatalytic hydrogen production from water under visible light irradiation over the photocatalyst of CoP2 loaded red phosphorus.Type: GrantFiled: September 11, 2013Date of Patent: January 27, 2015Assignee: The Chinese University of Hong KongInventors: Chai Mei Jimmy Yu, Feng Wang
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Publication number: 20150021499Abstract: The present invention includes upconversion materials such as lanthanide-sensitized oxides that are useful for converting low-energy photons into high-energy photons. Because silicon-based solar cells have an intrinsic optical band-gap of 1.1 eV, low-energy photons having a wavelength longer than 1100 nm, e g., infrared photons, cannot be absorbed by the solar cell and used for photovoltaic energy conversion. Only those photons that have an energy equal to or greater than the solar cell's band gap, e.g., visible photons, can be absorbed and used for photovoltaic energy conversion. The oxides described herein transform photons having an energy less than the energy of a solar cell's band gap into photons having an energy equal to or greater than the energy of the band gap. When these oxides are incorporated into a solar cell, they provide more photons for photovoltaic energy conversion than otherwise would be available in their absence.Type: ApplicationFiled: May 15, 2014Publication date: January 22, 2015Applicant: The Chinese University of Hong KongInventors: Jianfang Wang, Junxin Wang, Tian Ming
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Patent number: 8938157Abstract: A digital chip system, digital chip, methods for embedding data and methods for extracting data are provided. In some embodiments, a digital chip includes: a watermark encoder digital chip configured to receive one or more watermark bits and generate a stego-video; and a watermark decoder digital chip configured to receive the stego-video and extract the one or more watermark bits from the stego-video. In some embodiments, the digital chip also includes: a video decoder controller digital chip configured to receive raw video data, wherein the raw video data is received from a video decoder; a configuration controller digital chip configured to configure the video decoder; a memory management unit digital chip configured to store at least one of the raw video frame, the raw video data or the stego-video; and an Ethernet controller unit digital chip configured to store or access the raw video or stego-video.Type: GrantFiled: February 23, 2010Date of Patent: January 20, 2015Assignee: City University of Hong KongInventor: Lee Ming Cheng
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Patent number: 8935561Abstract: Technologies are generally described for systems and methods effective to schedule repair (e.g., allocate repair resources, determine a repair sequence, etc.) of a system effected by a large-scale failure caused by a natural disaster, malicious attack, faulty components, or the like. In an example, the system can generate a schedule that indicates amounts of repair resources allocated for repair of specific components of a disrupted system as well as a time or sequence in which the components are to be repaired. The schedule, in some instance, can operate to maximize an amount of restoration, at each stage of a recovery process, relative to the characteristic of the disrupted system. For example, with a communications network as the disrupted system, the schedule can maximize the amount of total traffic flow capacity recovered after respective steps of the recovery process.Type: GrantFiled: February 23, 2012Date of Patent: January 13, 2015Assignee: City University of Hong KongInventor: Jianping Wang
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Patent number: 8927225Abstract: Disclosed is an assay (method) to quantify the amounts of catecholamine-O-methyltransferase (COMT) protein in samples, such as extracts from cell cultures, body fluids, tissues, and environmental samples. It uses novel agents (anti-NE, COMT-NE, or COMT-epitope-NE) in combination with two previously described agents (anti-COMT and COMT) in a competitive ELISA system to achieve this aim.Type: GrantFiled: September 8, 2009Date of Patent: January 6, 2015Assignee: The University of Hong KongInventors: Shu Leong Ho, Wing Lok Ho, David Boyer Ramsden
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Patent number: 8928429Abstract: Multiple-way ring cavity power combiners and power dividers are disclosed. In one aspect, the disclosed ring cavity power combiners and power dividers can support a large number of devices by providing a large number of power-combining or power-dividing ports. In another aspect, the disclosed embodiments describe implementations employing a ring cavity that result in demonstrated performance characteristics suitable for UWB applications. Advantages provided include suppressing higher order modes and low losses among other advantages.Type: GrantFiled: May 17, 2011Date of Patent: January 6, 2015Assignee: City University of Hong KongInventors: Kaijun Song, Xue Quan
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Patent number: 8927216Abstract: This application describes the discovery that, in a pregnant woman, certain genes (such as RASSF1A, APC, CASP8, RARB, SCGB3A1, DAB2IP, PTPN6, THY1, TMEFF2, and PYCARD) originated from a fetus are highly methylated, whereas the same genes of maternal origin are unmethylated. This discovery allows the easy detection of one or more of these methylated fetal genes in a biological sample from a pregnant woman, serving as a universal indicator of the presence of fetal DNA in the sample. These fetal methylation markers are particularly useful as positive controls for a non-invasive analytical process during which the quality and quantity of fetal DNA are monitored. These newly identified fetal markers can also be measured directly for diagnosis of certain pregnancy-related conditions.Type: GrantFiled: September 14, 2012Date of Patent: January 6, 2015Assignee: The Chinese University of Hong KongInventors: Yuk-Ming Dennis Lo, Rossa Wai Kwun Chiu, Stephen Siu Chung Chim, Chunming Ding, Kwan Chee Chan, Hing Nam Ivy Wong, Ka Chun Ryan Yuen
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Patent number: 8923270Abstract: A sum-of-delays algorithm in a digital mobile communication bandwidth-varying network is employed to estimate link buffer size and queue length in an undying network connection. In particular, mechanisms associated with the process compensate for link bandwidth variations. In a particular embodiment, passive estimation are employed to implement the process by simply measuring the in-band data packet timings to perform estimation, thus eliminating the need for transmission of extra measurement packets. This method enables the integration of the link buffer size estimation algorithm into existing transport protocols such as TCP to optimize flow and congestion controls. As part of the invention, a new congestion control method called TCP Queue-length-Adaptive (TCP-QA) is developed to employ the sum-of-delays algorithm in the TCP sender computer to control the data flow in a TCP connection.Type: GrantFiled: September 24, 2012Date of Patent: December 30, 2014Assignee: The Chinese University of Hong KongInventors: Yiu Bun Jack Lee, Chi Fung Chan
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Patent number: 8917057Abstract: There is provided a planar inductive battery charging system designed to enable electronic devices to be recharged. The system includes a planar charging module having a charging surface on which a device to be recharged is placed. Within the charging module and parallel to the charging surface is at least one and preferably an array of primary windings that couple energy inductively to a secondary winding formed in the device to be recharged. The invention also provides secondary modules that allow the system to be used with conventional electronic devices not formed with secondary windings.Type: GrantFiled: October 10, 2011Date of Patent: December 23, 2014Assignee: City University of Hong KongInventor: Shu Yuen Ron Hui
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Patent number: 8913409Abstract: Systems, methods, and devices that employ self-driven gate-drive circuitry to facilitate controlling power switches to emulate a diode bridge to synchronously rectify a power signal are presented. A single-phase or multi-phase synchronous rectifier can comprise at least a first pair of switches of a first conducting path and a second pair of switches of a second conducting path that can form or emulate a diode bridge. To facilitate emulating turn-on and turn-off conditions of a diode, a switch can be turned on when voltage across the switch is forward-biased and turned off when switch current is reversed; also, there can be at least one current-controlled switch in each conducting path. Self-driven gate-drive circuitry employs low power components that can facilitate controlling respective switching of the at least first pair and second pair of switches, wherein switching of the switches is also controlled at start-up to emulate a diode bridge.Type: GrantFiled: October 6, 2010Date of Patent: December 16, 2014Assignee: City University of Hong KongInventors: Shu Yuen Ron Hui, Wenxing Zhong, Ho Wing Choi
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Patent number: 8906422Abstract: The invention provides a method for treating cancers that are dependent on cyclin D1 for proliferation, survival, metastasis and differentiation, involving administering a composition containing an effective amount of arsenic trioxide to an affected patient. The arsenic trioxide can be administered orally, for example, as a solution, suspension, syrup, emulsion, tablet, or capsule. The composition can also contain one or more pharmaceutically acceptable carriers and/or excipients.Type: GrantFiled: October 11, 2007Date of Patent: December 9, 2014Assignee: The University of Hong KongInventor: Yok-Lam Kwong
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Publication number: 20140357578Abstract: Compositions, methods, and kits are provided for reduction of (CAG)n-RNA mediated toxicity. Compositions, methods, and kits are also provided for treatment of polyglutamine diseases.Type: ApplicationFiled: June 2, 2014Publication date: December 4, 2014Applicant: The Chinese University of Hong KongInventor: Ho Yin Edwin Chan
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Publication number: 20140356321Abstract: Granulin-epithelin precursor (GEP), a pluripotent growth factor, is a hepatic oncofetal protein defining a cancer stem cell (CSC) population in liver cancer. The present invention provides the use of GEP inhibitors (including anti-GEP antibody) for inhibiting immune evasion by liver cancer cells and for eliminating liver cancer stem cells.Type: ApplicationFiled: May 30, 2014Publication date: December 4, 2014Applicant: THE UNIVERSITY OF HONG KONGInventors: Siu Tim Cheung, Sheung-Tat Fan, Phyllis Fung Yi Cheung
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Publication number: 20140347896Abstract: A dc link module for a power circuit includes a first connector for connecting to a first power conversion circuit, a second connector for connecting to a second power conversion circuit, wherein the second power conversion circuit is connected to a load circuit arranged to at least intermittently operate as a power source to the power circuit, at least one dc link capacitors arranged between said first connector and said second connector for processing a voltage signal received at said first connector or said second connector, and at least one voltage compensation circuits arranged between said first connector and said second connector, said one or more voltage compensation circuits arranged to generate a voltage signalType: ApplicationFiled: July 4, 2012Publication date: November 27, 2014Applicant: CITY UNIVERSITY OF HONG KONGInventors: Shu-Hung Henry Chung, Huai Wang