Patents Assigned to The University of Hull
  • Patent number: 10877164
    Abstract: The present invention relates to a method and apparatus for detecting radioactivity. In particular, but not exclusively, the present invention relates to the detection of radioactivity in a target fluid in a fluid communication passageway using a region of scintillator material (130) to provide light responsive to the presence of radioactive material and at least one silicon photomultiplier (SiPM) (150) for providing an output signal responsive to the light provided by the scintillator material.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: December 29, 2020
    Assignee: The University of Hull
    Inventors: Stephen James Archibald, David Jenkins, Nuray Yavuzkanat, Mohammad Mehdi Nasr Esfahani, Mark Tarn, Nicole Pamme
  • Patent number: 10283120
    Abstract: A method of producing output indicative of the content of speech or mouthed speech from movement of speech articulators is described. The method may including fixing a plurality of magnets respectively to a plurality of speech articulators of a human individual. Providing a support. Providing a plurality of signal magnetic field sensors. Providing at least three reference magnetic field sensors orientated differently from one another with respect to the Earth's magnetic field. The signal and reference magnetic field sensors being fixed to the support which holds the sensors in fixed spatial relationships to one another. Producing, over a period of time, a respective signal from each signal magnetic field sensor and a respective signal from each reference magnetic field sensor. Obtaining, over the period of time, for each said signal magnetic field sensor signal, a respective correction value.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: May 7, 2019
    Assignee: The University of Hull
    Inventors: James Michael Gilbert, Lam Aun Cheah, Jie Bai
  • Publication number: 20180094192
    Abstract: The invention provides photopolymerisable or photocrosslinkable reactive mesogen for forming a hole-transporting or light emitting polymer network, said mesogen having the structure (III) wherein M is a chromophoric aromatic or heterocyclic moiety; A1 and A2 are carbazole groups substituted in the 3-position of the carbazole ring, and may be the same or different; S1 and S2 are spacers, and may be the same or different; B1 and B2 are polymerisable groups, and may be the same or different; and m and n are independently integers from 1 to 10.
    Type: Application
    Filed: April 14, 2016
    Publication date: April 5, 2018
    Applicant: UNIVERSITY OF HULL
    Inventors: STEPHEN MALCOLM KELLY, MARY O'NEILL, STUART PAUL KITNEY
  • Patent number: 9716229
    Abstract: The invention provides a photopolymerisable or photocrosslinkable reactive mesogen for forming a charge transporting or light emitting polymer network, the mesogen having an asymmetric structure (II): B1-S1-A1-M-(A-S-B)n (II) wherein: A and A1 are chromophores; S and S1 are spacers; B and B1 are endgroups which are susceptible to photopolymerisation or photocrosslinking; M is a non-chromophoric aliphatic, alicyclic or aromatic moiety; and n is an integer from 1 to 3; wherein, when the value of n is greater than 1, each of the groups A, S and B may be the same or different. Preferably, M is of the formula Y?Zm, wherein Y is an aliphatic, alicyclic, aromatic or heterocyclic moiety, Z is an aliphatic linking group and m is an integer from 2 to 4, and wherein each of the Z groups may be the same or different.
    Type: Grant
    Filed: January 20, 2012
    Date of Patent: July 25, 2017
    Assignee: UNIVERSITY OF HULL
    Inventors: Mary O'Neill, Stephen Malcolm Kelly, Stuart Paul Kitney
  • Patent number: 9675448
    Abstract: A tool for facilitating insertion of a speech valve with a flexible retention flange into a fistula between the trachea and the esophagus of a human patient. The tool has a wall curved to define a passage having opposed open first and second passage ends and an axis extending therebetween. The wall has an external surface insertable into a fistula between the trachea and esophagus and defining a slot which extends from the passage to the external surface of the wall. The slot has an opening at the first passage end extending from the first passage end to at least a part of the way to the second passage end and at least a portion of the slot progresses angularly around the axis.
    Type: Grant
    Filed: October 22, 2010
    Date of Patent: June 13, 2017
    Assignee: THE UNIVERSITY OF HULL
    Inventors: Michael Fagan, Jean Marie Steeve Lamvohee, Catherine Dobson
  • Patent number: 9101933
    Abstract: An integrated gel based microfluidic sample processing device, suitable for forensic investigations at the scene of a crime, including a substrate having a plurality of micro-channels to form at least a DNA extraction chamber in fluidic cooperation with an amplification chamber which in turn is in fluidic cooperation with a separation and detection channel. The micro-channels containing a DNA extraction material and gel based reaction reagents necessary for processing the sample. The device further having electrical contacts for coupling to an external power source and capable of inducing electro-kinetic manipulation of the gel based reagents and DNA extracted from the sample throughout the device.
    Type: Grant
    Filed: October 12, 2009
    Date of Patent: August 11, 2015
    Assignee: University of Hull
    Inventor: Stephen John Haswell
  • Patent number: 8828464
    Abstract: A whitened exine shell having a degree of whiteness (L*) of greater than 65 measured under D 65 illumination. The shell can be used as a delivery vehicle for an active substance, or as an antioxidant. It can be used in a method of surgery, therapy or diagnosis. The invention provides a formulation containing the whitened exine shell together with an active substance; and a method for preparing the shell by isolating an exine shell from a naturally occurring spore under treatment conditions which do not include aceto lysis, and treating the isolated shell or a precursor thereof with a bleaching composition.
    Type: Grant
    Filed: July 9, 2009
    Date of Patent: September 9, 2014
    Assignee: University of Hull
    Inventors: Stephen Atkin, Stephen Beckett, Grahame Mackenzie
  • Patent number: 8784851
    Abstract: Topical formulation containing an active substance which is chemically or physically bound to, or encapsulated within, an exine shell of a naturally occurring spore. The active substance can be released from the exine shell on application to a living or non-living surface. The invention may be used to provide gradual release of an active substance over a period of time subsequent to application of the formulation to the surface.
    Type: Grant
    Filed: July 27, 2006
    Date of Patent: July 22, 2014
    Assignee: University of Hull
    Inventors: Stephen Lawrence Atkin, Stephen Thomas Beckett, Grahame Mackenzie
  • Patent number: 8600471
    Abstract: The present disclosure relates to catheters, for example a catheter which is adapted such that the user is able to determine whether it has been correctly positioned within 5 the subject. Also included in the present disclosure are means for detecting the position of the catheter and combinations of a catheter and processors for determining the positioning of the catheter. The present disclosure also relates to methods of determining the position of a catheter in, for example, a human or animal body.
    Type: Grant
    Filed: June 8, 2007
    Date of Patent: December 3, 2013
    Assignee: The University of Hull
    Inventors: Jay Wadhawan, John Greenman, Magdi El-Habbal, Linda Shields, Cameron Imrie, Barbara Elliott
  • Publication number: 20130299805
    Abstract: The invention provides a photopolymerisable or photocrosslinkable reactive mesogen for forming a charge transporting or light emitting polymer network, the mesogen having an asymmetric structure (II): B1—S1-A1-M-(A-S—B)n (II) wherein: A and A1 are chromophores; S and S1 are spacers; B and B1 are endgroups which are susceptible to photopolymerisation or photocrosslinking; M is a non-chromophoric aliphatic, alicyclic or aromatic moiety; and n is an integer from 1 to 3; wherein, when the value of n is greater than 1, each of the groups A, S and B may be the same or different. Preferably, M is of the formula Y—Zm, wherein Y is an aliphatic, alicyclic, aromatic or heterocyclic moiety, Z is an aliphatic linking group and m is an integer from 2 to 4, and wherein each of the Z groups may be the same or different.
    Type: Application
    Filed: January 20, 2012
    Publication date: November 14, 2013
    Applicant: University of Hull
    Inventors: Mary O'Neill, Stuart Paul Kitney
  • Publication number: 20130248366
    Abstract: A method of amplifying nucleic acid includes providing a microfluidic device having a space therein. The space is filled with a gel medium. Reagents for carrying out a PCR reaction are supported within the matrix of the gel medium within the space. A nucleic acid containing sample is brought into contact with the gel medium. The sample having whole cells or cell lysate without any prior separation of the nucleic acid from other components of the cells. PCR amplification of nucleic acid from the sample is performed in the space using the PCR reagents.
    Type: Application
    Filed: September 21, 2011
    Publication date: September 26, 2013
    Applicant: THE UNIVERSITY OF HULL
    Inventors: Stephen John Haswell, Kirsty Jane Shaw, Peter Docker
  • Patent number: 8398711
    Abstract: A speech valve comprises a generally cylindrical body and a closure member which is slidably movable within the body between a closed position and an open position. The valve body and the closure member are formed of a rigid, smooth material which is resistant to the growth of biofilm such as a ceramic. A particular suitable ceramic is partially stabilised zirconia. The valve body is provided with an outer sleeve which is provided with radially outward extending annular flanges, which are used to retain the speech valve in a fistula between the oesophagus and the trachea.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: March 19, 2013
    Assignee: University of Hull
    Inventors: Michael J. Fagan, Stephen R. Ell, Timothy A. Paget, Catherine A. Dobson, Zahra N. Mahmoud
  • Publication number: 20120215306
    Abstract: A tool for facilitating insertion of a speech valve with a flexible retention flange into a fistula between the trachea and the oesophagus of a human patient. The tool has a wall curved to define a passage having opposed open first and second passage ends and an axis extending therebetween. The wall has an external surface insertable into a fistula between the trachea and oesophagus and defining a slot which extends from the passage to the external surface of the wall. The slot has an opening at the first passage end extending from the first passage end to at least a part of the way to the second passage end and at least a portion of the slot progresses angularly around the axis.
    Type: Application
    Filed: October 22, 2010
    Publication date: August 23, 2012
    Applicant: THE UNIVERSITY OF HULL
    Inventors: Michael Fagan, Jean Marie Steeve Lamvohee, Catherine Dobson
  • Patent number: 8034800
    Abstract: A compound of Formulae (1), (2) or (3), A1-Ph (1) or A1-Ar-A2 (2) or A1-(A2)A?-A3 (3) wherein A1, A2 and A3 are selected from Formulae 4, 5 and 6: or a salt whereof; wherein Ar is selected from the group consisting of 1,2-phenyl, 1,3-phenyl and 1,4-phenyl optionally substituted with one or more methyl groups; m and n are independently integers from 0 to 1; Ph is phenyl, optionally substituted with one or more methyl groups; Ar1 is trisubstituted phenyl optionally substituted with one or more phenyl groups; and R1, R2 and R3 are independently selected from the group consisting of H, Me and linear chain C2-C4 alkyl.
    Type: Grant
    Filed: June 10, 2005
    Date of Patent: October 11, 2011
    Assignee: University of Hull
    Inventors: Stephen James Archibald, Elizabeth Amie Lewis, Timothy J. Hubin
  • Publication number: 20110244467
    Abstract: An integrated gel based microfluidic sample processing device, suitable for forensic investigations at the scene of a crime, including a substrate having a plurality of micro-channels to form at least a DNA extraction chamber in fluidic cooperation with an amplification chamber which in turn is in fluidic cooperation with a separation and detection channel. The micro-channels containing a DNA extraction material and gel based reaction reagents necessary for processing the sample. The device further having electrical contacts for coupling to an external power source and capable of inducing electro-kinetic manipulation of the gel based reagents and DNA extracted from the sample throughout the device.
    Type: Application
    Filed: October 12, 2009
    Publication date: October 6, 2011
    Applicant: UNIVERSITY OF HULL
    Inventor: Stephen John Haswell
  • Publication number: 20110002984
    Abstract: A formulation containing an active substance encapsulated within an exine shell of a naturally occurring spore, together with a protective additive which is also encapsulated within the exine shell.
    Type: Application
    Filed: December 17, 2008
    Publication date: January 6, 2011
    Applicant: UNIVERSITY OF HULL
    Inventors: Stephen Lawrence Atkin, Stephen Thomas Beckett, Alberto Diego-Taboada, Grahame MacKenzie
  • Patent number: 7846654
    Abstract: This invention provides the use of an exine shell of a naturally occurring spore, or a fragment thereof, as an antioxidant, for instance in a composition or formulation containing an active substance. Also provided is a method for reducing rancidity, or other oxidative degradation, of a substance, composition, or formulation, by encapsulating the substance, composition, or formulation in, or chemically binding it to, or mixing it with, an exine shell of a naturally occurring spore or a fragment thereof.
    Type: Grant
    Filed: January 25, 2008
    Date of Patent: December 7, 2010
    Assignee: University of Hull
    Inventors: Stephen Lawrence Atkin, Stephen Thomas Beckett, Grahame Mackenzie
  • Patent number: 7820907
    Abstract: A photovoltaic cell is provided. The photovoltaic cell can be an interconnecting liquid crystalline polymer network. Reactive mesogens of the formula B-S-A-S-B wherein A is a chromophore, S is a spacer and B is an end group susceptible to polymerization are used in the manufacture of the interconnecting liquid crystalline polymer network.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: October 26, 2010
    Assignee: University of Hull
    Inventors: Mary O'Neill, Stephen Malcolm Kelly, Miguel Angel Carrasco-Orozo
  • Patent number: 7674609
    Abstract: Crypthecodinium cohnii, or microorganisms derived from Crypthecodinium cohnii, are grown in a culture medium including propionic acid. The propionic acid increases the production of one or more of dry cell weight, total lipid and docosahexaenoic acid.
    Type: Grant
    Filed: February 4, 2002
    Date of Patent: March 9, 2010
    Assignee: The University of Hull
    Inventors: Colin Ratledge, Alistair James Anderson, Kanagasooriyam Kanagachandran
  • Publication number: 20090283098
    Abstract: A speech valve comprises a generally cylindrical body and a closure member which is slidably movable within the body between a closed position and an open position. The valve body and the closure member are formed of a rigid, smooth material which is resistant to the growth of biofilm such as a ceramic. A particular suitable ceramic is partially stabilised zirconia. The valve body is provided with an outer sleeve which is provided with radially outward extending annular flanges, which are used to retain the speech valve in a fistula between the oesophagus and the trachea.
    Type: Application
    Filed: October 18, 2007
    Publication date: November 19, 2009
    Applicant: THE UNIVERSITY OF HULL
    Inventors: Michael J. Fagan, Stephen R. Ell, Timothy A. Paget, Catherine A. Dobson, Zahra N. Mahmoud